Journal of Ophthalmic and Optometric Sciences

Vol. 9 No. 2 (2025)

Association between Central Retinal Vein Occlusion and Mental Health Disorders

Journal of Ophthalmic and Optometric Sciences, Vol. 9 No. 2 (2025), 5 April 2025
https://doi.org/10.22037/joos.v9i2.50604

Abstract

Purpose: To investigate the association between central retinal vein occlusion (CRVO) and the presence of mental health disorders.
Patients and Methods: This observational study included 120 patients with CRVO, aged 48–82 years. Psychiatric assessment was performed using standardized tools, including the Beck Anxiety Inventory (BAI) and the Beck Depression Inventory (BDI), to evaluate the prevalence of depression, anxiety, and related mental health disorders.
Results: Of the 120 patients, 71 (59.16 %) were diagnosed with mental health disorders, most commonly depression and anxiety. The findings indicate that more than half of patients with CRVO experience significant psychiatric comorbidities.
Conclusion: Mental health disorders, particularly depression and anxiety, are highly prevalent in patients with CRVO. These results underscore the need for routine psychiatric evaluation and integrated care strategies to improve overall outcomes in affected individuals.

Keywords:
  • Retinal Vein Occlusion
  • Central
  • Depression
  • Anxiety
  • Mental Health
  • Comorbidity
  • Mental Disorders

How to Cite

Shushtarian, S. M. M., & Eslami Vaghar , M. (2025). Association between Central Retinal Vein Occlusion and Mental Health Disorders. Journal of Ophthalmic and Optometric Sciences, 9(2). https://doi.org/10.22037/joos.v9i2.50604

References

Davis MT, Holmes SE, Pietrzak RH, Esterlis I. Neurobiology of Chronic Stress-Related Psychiatric Disorders: Evidence from Molecular Imaging Studies. Chronic Stress (Thousand Oaks). 2017;1:2470547017710916.

Chan KL, Poller WC, Swirski FK, Russo SJ. Central regulation of stress-evoked peripheral immune responses. Nat Rev Neurosci. 2023;24(10):591-604.

Steptoe A, Kivimäki M. Stress and cardiovascular disease. Nat Rev Cardiol. 2012;9(6):360-70.

Sabel BA, Wang J, Cárdenas-Morales L, Faiq M, Heim C. Mental stress as consequence and cause of vision loss: the dawn of psychosomatic ophthalmology for preventive and personalized medicine. EPMA J. 2018;9(2):133-60.

Kolar P. Risk factors for central and branch retinal vein occlusion: a meta-analysis of published clinical data. J Ophthalmol. 2014;2014:724780.

Nicholson L, Talks SJ, Amoaku W, Talks K, Sivaprasad S. Retinal vein occlusion (RVO) guideline: executive summary. Eye (Lond). 2022;36(5):909-12.

Si S, Lin J, Guo R, Chen A, Ji Y. Impact of high-risk optic disc on central retinal vein occlusion in patients with metabolic disorders. Front Physiol. 2024;15:1424144.

Lee JY, Wang SM, Jeon SH, Kim MH, Han KD, Roh YJ. The Risk of Retinal Vein Occlusion in Young Patients with Mental Disorders: A Nationwide Cohort Study. J Clin Med. 2023;12(14):4874.

Ha M, Han K, Jung Y, Kim D, Paik JS, Na KS. Is retinal vein occlusion associated with depression symptoms?: A nationwide cohort study. Medicine (Baltimore). 2021;100(32):e26937.

Altemus M, Sarvaiya N, Neill Epperson C. Sex differences in anxiety and depression clinical perspectives. Front Neuroendocrinol. 2014;35(3):320-30.

Ramin S, Rostami F, Ahmadieh H, Daftarian N, Nourinia R, Abbasi A, et al. Vision-related quality of life in patients with retinal vein occlusion. Int Ophthalmol. 2024;44(1):114.

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