Premature Centromere Division and Spontaneous Abortion
International Journal of Medical Toxicology and Forensic Medicine,
Vol. 3 No. 2(Spring) (2013),
10 June 2013
,
Page 67-70
https://doi.org/10.22037/ijmtfm.v3i2(Spring).4012
Abstract
Premature Centromere Division (PCD) was observed in the chromosomes of metaphase spreads in a patient with the history of recurrent abortions. Short term leukocyte cultures were set up with blood sample from the woman with a history of recurrent abortions for the past four consequent years. 25 % of the metaphase spreads screened displayed premature centromere division of the chromosomes in each of the cells. This abnormal behavior of the centromeres may predispose the individual to cell division errors due to chromosome instability and the consequences of which may be a spontaneous abortion.- Cell division
- Chromosomes
- Chromatids
- Premature centromere division
- Non-disjunction
- Abortion
How to Cite
References
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