Diffuse Multifocal Bilateral Dysembryoplastic Neuroepithelial Tumor: A Very Unusual Case Report
International Clinical Neuroscience Journal,
Vol. 7 No. 2 (2020),
10 March 2020
,
Page 109-112
Abstract
Dysembryoplastic neuroepithelial tumor (DNT) considered as a benign cortical Glioneuronal neoplasm of children or young adults, typically present with drug-resistant focal epilepsy. DNTs are usually located in the temporal lobe but can found in any part of the supratentorial brain cortex. Multifocal DNTs have rarely reported. Here we present an eight years old boy with two years follow up, having a somewhat stable diffuse multinodular DNT of the most significant spatial extent that may have reported, involving cortical and subcortical left temporo-occipital lobe, bilateral basal ganglia and thalamus, presenting with headache, short stature, and behavioral disorder.- Dysembryoplastic Neuroepithelial Tumor
- Multifocal
- Diffuse
- Brain Tumor
- Bilateral
How to Cite
References
Daumas-Duport C, Scheithauer BW, Chodkiewicz JP, Laws Jr ER, Vedrenne C. Dysembryoplastic neuroepithelial tumor: a surgically curable tumor of young patients with intractable partial seizures: report of thirty-nine cases. Neurosurgery. 1988 Nov 1;23(5):545-56.
Suh YL. Dysembryoplastic neuroepithelial tumors. Journal of pathology and translational medicine. 2015 Nov;49(6):438.
Louis DN, Perry A, Reifenberger G, Von Deimling A, Figarella-Branger D, Cavenee WK, Ohgaki H, Wiestler OD, Kleihues P, Ellison DW. The 2016 World Health Organization classification of tumors of the central nervous system: a summary. Acta neuropathologica. 2016 Jun 1;131(6):803-20.
Sina F, Poranian M, Razmeh S, Talesh JT. Multifocal Dysembryoplastic Neuroepithelial Tumor: A Report of a Rare Case. Reports of Radiotherapy and Oncology. 2018 Dec;5(1).
Yang AI, Khawaja AM, Ballester‐Fuentes L, Pack SD, Abdullaev Z, Patronas NJ, Inati SK, Theodore WH, Quezado MM, Zaghloul KA. Multifocal dysembryoplastic neuroepithelial tumours associated with refractory epilepsy. Epileptic Disorders. 2014 Sep;16(3):328-32.
Schittenhelm J, Mittelbronn M, Wolff M, Truebenbach J, Will BE, Meyermann R, Beschorner R. Multifocal dysembryoplastic neuroepithelial tumor with signs of atypia after regrowth. Neuropathology. 2007 Aug;27(4):383-9.
Krossnes BK, Wester K, Moen G, Mørk SJ. Multifocal dysembryoplastic neuroepithelial tumour in a male with the XYY syndrome. Neuropathology and applied neurobiology. 2005 Oct;31(5):556-60.
Whittle IR, Dow GR, Lammie GA, Wardlaw J. Dsyembryoplastic neuroepithelial tumour with discrete bilateral multifocality: further evidence for a germinal origin. British journal of neurosurgery. 1999 Jan 1;13(5):508-11.
White RD, Kanodia AK, Sammler EM, Brunton JN, Heath CA. Multifocal dysembryoplastic neuroepithelial tumour with intradural spinal cord lipomas: report of a case. Case reports in radiology. 2011;2011.
Lu JQ, Scheithauer BW, Sharma P, Scott JN, Parney IF, Hader W, Burger PC, Clark AW. MULTIFOCAL COMPLEX GLIONEURONAL TUMOR IN AN ELDERLY MAN: AN AUTOPSY STUDY. Neurosurgery. 2009 Jun 1;64(6):E1193-5.
Cosson RS, Varlet P, Beuvon F, Duport CD, Devaux B, Chassoux F, Fredy D, Meder JF. Dysembryoplastic neuroepithelial tumors: CT, MR findings and imaging follow-up: a study of 53 cases. Journal of neuroradiology. 2001 Dec 1;28(4):230-40.
Daumas-Duport C, Varlet P, Dysembryoplastic neuroepithelial tumors. Rev Neurol (Paris). 2003;59:622-36.
Gyure KA, Sandberg GD, Prayson RA, Morrison AL, Armstrong RC, Wong K. Dysembryoplastic neuroepithelial tumor: an immunohistochemical study with myelin oligodendrocyte glycoprotein. Archives of pathology & laboratory medicine. 2000 Jan;124(1):123-6.
Luzzi S, Elia A, Del Maestro M, Elbabaa SK, Carnevale S, Guerrini F, Caulo M, Morbini P, Galzio R. Dysembryoplastic neuroepithelial tumors: what you need to know. World Neurosurg. 2019 Jul 1;127:255-65.
Rivera B, Gayden T, Carrot-Zhang J, Nadaf J, Boshari T, Faury D, Zeinieh M, Blanc R, Burk DL, Fahiminiya S, Bareke E. Germline and somatic FGFR1 abnormalities in dysembryoplastic neuroepithelial tumors. Acta neuropathologica. 2016 Jun 1;131(6):847-63.
- Abstract Viewed: 256 times
- PDF Downloaded: 278 times