Safety and Efficacy of Clomiphene Citrate and L-Carnitine in Idiopathic Male Infertility: A Comparative Study
Urology Journal,
Vol. 7 No. 3 (2010),
15 September 2010
,
Page 188-193
https://doi.org/10.22037/uj.v7i3.750
Abstract
PURPOSE: To compare the effects of L-carnitine with clomiphene citrate in idiopathic infertile men. MATERIALS AND METHODS: Fifty-two men with idiopathic infertility were recruited in this randomized controlled trial. They were randomly assigned into 2 treatment groups, group 1 (n = 20) and group 2 (n = 32), who received L-carnitine 25 mg/day and clomiphene citrate 2 gr/day, respectively, for a period of 3 months. RESULTS: Comparing the effect of L-carnitine and clomiphene on sperm parameters before and after the treatment, both medications had influence on sperm count and motility (P = .01). L-carnitine significantly increased the semen volume (P = .001), while clomiphene citrate was significantly associated with the motility percentage and normal morphology (P = .008). CONCLUSION: It seems that the use of clomiphene citrate and L-carnitine, either individually or in combination, as the first step of idiopathic male infertility treatment is reasonable, safe, and effective.How to Cite
Moradi, M., Moradi, A., Alemi, M., Ahmadnia, H., Abdi, H., Ahmadi, A., & Bazargan-Hejazi, S. (2010). Safety and Efficacy of Clomiphene Citrate and L-Carnitine in Idiopathic Male Infertility: A Comparative Study. Urology Journal, 7(3), 188–193. https://doi.org/10.22037/uj.v7i3.750
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