A A Prospective Study to Investigate the Effect of Fesoterodine Treatment on Quality of Life, Anxiety, and Depression in Urge-Type Urinary Incontinence Quality of life, mood disorders and urinary incontinence
23 February 2021
Purpose: Urinary incontinence (UI) is a fundamental health problem, can occur at any age but is especially common in older women. Depression and anxiety are also considerable problems for the elderly. UI is one of the geriatric syndromes that are thought to be related to depression and quality of life (QOL).
Materials and methods: This prospective study was conducted for a period of 2 months from February 2020 to April 2020. Women who applied to the outpatient clinic of geriatrics with UI symptoms were taken into the study. The type of UI was determined by using the 3 Incontinence Questions (3IQ). Only patients with urge incontinence were included in the study. Patients were evaluated for QOL, anxiety, depression, disability, and geriatric syndromes before and after treatment. Data analysis was done by using SPSS version 22.
Results: The study population was 42 women; the mean age was 69.7 +/- 4.3 years. QoL, anxiety, and depression symptoms, and ADL were revealed to be improved after treatment. ICIQ-SF, I-QOL, and HADs scores were associated with UI treatment when evaluated with one-way MANOVA (F [4, 79] =3.25, p=0.00, Wilk's Λ=0.859, partial η2=0.14).
Conclusion: UI is a common problem in the elderly. Patients usually hesitate to tell this complaint to even doctors. That situation affects their physical and psychological condition negatively. In this study, we reached that anticholinergic treatment (fesoterodine) improved ADL, QoL, and psychological symptoms. Those findings represented us that proper treatment of UI is critical for healthy aging.
- Anxiety, Depression, Quality of Life, Urinary Incontinence
How to Cite
2. Thomas TM, Plymat KR, Blannin J, Meade TW. Prevalence of urinary incontinence. Br Med J. 1980;281(6250):1243-1245. doi:10.1136/bmj.281.6250.1243
3. Delancey JOL, Ashton-Miller JA. Pathophysiology of Adult Urinary Incontinence. Gastroenterology. 2004;126(1):23-32. doi:10.1053/j.gastro.2003.10.080
4. Minassian VA, Devore E, Hagan K, Grodstein F. Severity of urinary incontinence and effect on quality of life in women by incontinence type. Obstet Gynecol. 2013;121(5):1083-1090. doi:10.1097/AOG.0b013e31828ca761
5. Goode PS, Burgio KL, Richter HE. CLINICIAN ’ S CORNER Incontinence in Older Women. Care Aging Patient From Evid To Action Clin. 2010;35233.
6. Sahin-Onat S, Unsal-Delialioǧlu S, Güzel O, Uçar D. Relationship between urinary incontinence and quality of life/depression in elderly patients. J Clin Gerontol Geriatr. 2014;5(3):86-90. doi:10.1016/j.jcgg.2014.03.002
7. Murukesu RR, Singh DKA, Shahar S. Urinary incontinence among urban and rural community dwelling older women: Prevalence, risk factors and quality of life. BMC Public Health. 2019;19(Suppl 4):1-11. doi:10.1186/s12889-019-6870-6
8. Karmakar D, Mostafa A, Abdel-Fattah M. A new validated score for detecting patient-reported success on postoperative ICIQ-SF: a novel two-stage analysis from two large RCT cohorts. Int Urogynecol J. 2017;28(1):95-100. doi:10.1007/s00192-016-3070-0
9. Khan MJ, Omar MA, Laniado M. Diagnostic agreement of the 3 incontinence questionnaire to video-urodynamics findings in women with urinary incontinence. Cent Eur J Urol. 2018;71(1):84-91. doi:10.5173/ceju.2018.1622
10. Chen G, Tan JT, Ng K, Iezzi A, Richardson J. Mapping of Incontinence Quality of Life (I-QOL) scores to Assessment of Quality of Life 8D (AQoL-8D) utilities in patients with idiopathic overactive bladder. Health Qual Life Outcomes. 2014;12(1):1-8. doi:10.1186/s12955-014-0133-0
11. Ding T, Wang X, Fu A, Xu L, Lin J. Anxiety and depression predict unfavorable survival in acute myeloid leukemia patients. Med (United States). 2019;98(43):1-7. doi:10.1097/MD.0000000000017314
12. Mitchell AJ. A meta-analysis of the accuracy of the mini-mental state examination in the detection of dementia and mild cognitive impairment. J Psychiatr Res. 2009. doi:10.1016/j.jpsychires.2008.04.014
13. Shelkey M, Wallace M. Katz Index of Independence in Activities of Daily Living (ADL). Director. 2000. doi:10.1097/00004045-200105000-00020
14. Bauer JM, Kaiser MJ, Anthony P, Guigoz Y, Sieber CC. The mini nutritional assessment®-its history, today’s practice, and future perspectives. Nutr Clin Pract. 2008;23(4):388-396. doi:10.1177/0884533608321132
15. Oort Q, Taphoorn MJB, Sikkes SAM, Uitdehaag BMJ, Reijneveld JC, Dirven L. Evaluation of the content coverage of questionnaires containing basic and instrumental activities of daily living (ADL) used in adult patients with brain tumors. J Neurooncol. 2019;143(1):1-13. doi:10.1007/s11060-019-03136-9
16. Cao L, Chen S, Zou C, et al. A pilot study of the SARC-F scale on screening sarcopenia and physical disability in the Chinese older people. J Nutr Heal Aging. 2014;18(3):277-283. doi:10.1007/s12603-013-0410-3
17. Gąsior JS, Pawłowski M, Williams CA, Dąbrowski MJ, Rameckers EA. Assessment of maximal isometric hand grip strength in school-aged children. Open Med. 2018;13(1):22-28. doi:10.1515/med-2018-0004
18. Bahat G, Tufan A, Kilic C, et al. Cut-off points for weight and body mass index adjusted bioimpedance analysis measurements of muscle mass. Aging Clin Exp Res. 2019;31(7):935-942. doi:10.1007/s40520-018-1042-6
19. Bohannon RW, Wang YC. Four-Meter Gait Speed: Normative Values and Reliability Determined for Adults Participating in the NIH Toolbox Study. Arch Phys Med Rehabil. 2019;100(3):509-513. doi:10.1016/j.apmr.2018.06.031
20. Walston J, Buta B, Xue QL. Frailty Screening and Interventions: Considerations for Clinical Practice. Clin Geriatr Med. 2018;34(1):25-38. doi:10.1016/j.cger.2017.09.004
21. Lai HH, Shen B, Rawal A, Vetter J. The relationship between depression and overactive bladder/urinary incontinence symptoms in the clinical OAB population. BMC Urol. 2016;16(1):1-8. doi:10.1186/s12894-016-0179-x
22. Felde G, Engeland A, Hunskaar S. Urinary incontinence associated with anxiety and depression: the impact of psychotropic drugs in a cross-sectional study from the Norwegian HUNT study. BMC Psychiatry. 2020;20(1):1-10. doi:10.1186/s12888-020-02922-4
23. Smith AP. Female urinary incontinence and wellbeing: Results from a multi-national survey. BMC Urol. 2016;16(1):4-9. doi:10.1186/s12894-016-0140-z
24. Legendre G, Ringa V, Panjo H, Zins M, Fritel X. Incidence and remission of urinary incontinence at midlife: A cohort study. BJOG An Int J Obstet Gynaecol. 2015;122(6):816-823. doi:10.1111/1471-0528.12990
25. Lee H, Rhee Y, Choi KS. Urinary incontinence and the association with depression , stress , and self ‑ esteem in older Korean Women. Sci Rep. 2021:1-7. doi:10.1038/s41598-021-88740-4
26. Saboia DM, Firmiano MLV, Bezerra K de C, Neto JAV, Oriá MOB, Vasconcelos CTM. Impact of urinary incontinence types on women’s quality of life. Rev da Esc Enferm. 2017;51:1-8. doi:10.1590/S1980-220X2016032603266
27. Nygaard CC, Schreiner L, Morsch TP, Saadi RP, Figueiredo MF, Padoin AV. Urinary incontinence and quality of life in female patients with obesity. Rev Bras Ginecol e Obstet. 2018;40(9):534-539. doi:10.1055/s-0038-1670626
28. Pizzol D, Demurtas J, Celotto S, et al. Urinary incontinence and quality of life: a systematic review and meta-analysis. Aging Clin Exp Res. 2021;33(1):25-35. doi:10.1007/s40520-020-01712-y
29. Kiros T, Damtie S, Eyayu T, Tiruneh T. Review Article Bacterial Pathogens and Their Antimicrobial Resistance Patterns of Inanimate Surfaces and Equipment in Ethiopia : A Systematic Review and Meta-analysis. 2021;2021.
- Abstract Viewed: 0 times
- Just Accepted/6834 Downloaded: 0 times