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  3. Vol. 18 No. 06 (2021): November-December 2021
  4. ORIGINAL PAPER (ENDOUROLOGY AND STONE DISEASE)

Vol. 18 No. 06 (2021)

January 2022

Preoperative Urine Analysis is An Effective Tool to Predict Fever After Miniaturized Percutaneous Nephrolithotomy on Large Renal Stones

  • Ze-Hong Lu
  • Tsung Yen Lin
  • Ho Shiang Huang
  • Chan Jung Liu

Urology Journal, Vol. 18 No. 06 (2021), 18 January 2022 , Page 600-607
https://doi.org/10.22037/uj.v18i06.6463 Published: 2021-09-22

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Abstract

Purpose: To investigate the preoperative and intraoperative potential risk factors associated with miniaturized
percutaneous nephrolithotomy (mPCNL) fever in the treatment of patients with large renal stones.
Materials and Methods: All patients with renal stones larger than 2.5 cm, who had undergone mPCNL, were
included in the period between April 2018 and September 2019. Logistic regression analyses were performed to
identify clinical variables associated with post-operative fever (>38°C).
Results: A total of 53 patients were enrolled for whom the median maximal stone length was 3.08 cm. 24 (45%)
patients had a fever after mPCNL. Significantly more patients with urine WBC ≥ 27(/HPF) had a fever after surgery (p = 0.004). No significant between-group differences in urine cultures were found for the fever and non-fever groups (p = 0.094). Stepwise and multivariable logistic regression analyses all revealed that urine WBC ≥ 27(/HPF) is the only risk factor for developing post-mPCNL fever. Based on the highest body temperature, all of the patients were assigned into no fever, mild fever (37.5 ≤ Temp < 38.0), and fever groups, and an ordinal logistic regression analysis still supported the premise that the result of urine analysis is strongly associated with post-mPCNL fever.
Conclusion: Large renal stones are challenging to treat and associated with severe complications. Approximately 45% of large renal stone patients treated via mPCNL developed a fever. Urine WBC can easily and directly predict
the risk of fever.

Keywords:
  • Renal stones
  • Urolithiasis
  • Percutaneous nephrolithotomy
  • Urinary tract infection
  • Fever
  • Sepsis
  • Urine analysis
  • 6463/pdf

How to Cite

Lu, Z.-H., Lin, T. Y. ., Huang, H. S., & Liu, C. J. (2021). Preoperative Urine Analysis is An Effective Tool to Predict Fever After Miniaturized Percutaneous Nephrolithotomy on Large Renal Stones. Urology Journal, 18(06), 600–607. https://doi.org/10.22037/uj.v18i06.6463
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