The Association of Shorter Interval of Biopsy-Radical Prostatectomy and Surgical Difficulty
Vol. 15 No. 6 (2018),
AbstractPurpose: We discuss the safety and perioperative outcomes of a 2-week interval between prostate biopsy and laparoscopic radical prostatectomy (LRP).
Materials and Methods: We retrospectively reviewed the medical records of 182 patients with prostate cancer (PCa) who underwent transperitoneal LRP 2 weeks after prostate biopsy between 2012 and 2015. We evaluated the following perioperative outcomes: operative time, estimated blood loss (EBL), infection, conversion to open surgery, positive surgery margins (PSM), and complications. We also reviewed studies discussing a shorter interval between biopsy and LRP in peer-reviewed publications.
Results: The mean operative time and EBL were 100.2 min and 82.2 ml, respectively. There were no rectal injuries or conversions to open surgery, totally 19 (10.4%) patients experienced complications (Clavien-Dindo Grade I and II): fever occurred in six patients (3.3%), urinary leak in four (2.2%), incomplete paralytic ileus in four (2.2%), deep vein thrombosis in two (1.1%), and postoperative anemia in four. The average bedrest time after surgery was 2.5 days. PSM was detected in twenty-one patients (11.5%) . 167 patients (91.7%) recovered continence.
Follow-up ranged from 13-37 months, the biochemical recurrence (BCR) rate was 10.4% (19/182).The seven peer-reviewed studies we reviewed that a shorter interval was safe and did not influence surgical outcomes.
Conclusion: Our study shows that a 2-week interval between biopsy and LRP is safe and does not negatively affect surgical outcomes.
How to Cite
Chen, S., Jiang, G., Liu, N., Jiang, H., Zhang, L., Sun, C., Xu, B., Zhang, X., Yang, Y., Liu, J., Zhu, W., & Chen, M. (2018). The Association of Shorter Interval of Biopsy-Radical Prostatectomy and Surgical Difficulty. Urology Journal, 15(6), 344-347. https://doi.org/10.22037/uj.v0i0.4131
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