Shahid Behesthi University of Medical Sciences
  • Register
  • Login

Novelty in Biomedicine

  • Home
  • About
    • About journal
    • Indexing & Abstracting
    • Submissions
    • Editorial Team
    • Privacy Statement
    • Contact
  • Current
  • Archives
  • Announcements
Advanced Search
  1. Home
  2. Archives
  3. Vol. 13 No. 2 (2025): Vol. 13 No. 2 (2025): Spring2025
  4. Original Article

Vol. 13 No. 2 (2025)

April 2025

Comparison of leakage rate after sleeve gastrectomy compared with gastric bypass

  • Hadi Salehnia
  • Sara Rashki Ghalehnoo
  • Abbas Ali Dehghan

Novelty in Biomedicine, Vol. 13 No. 2 (2025), 19 April 2025 , Page 75-80
https://doi.org/10.22037/nbm.v13i2.46062 Published: 2025-04-19

  • View Article
  • Download
  • Cite
  • References
  • Statastics
  • Share

Abstract

Background: Gastric bypass and sleeve gastrectomy are two common types of bariatric surgery. Anastomotic leak is one of the common and fatal complications of these surgeries. The current study compared the leakage rate after sleeve gastrectomy and gastric bypass.

Materials and Methods: This cross-sectional study was performed on patients who underwent bariatric surgery in Mortaz and Mojibinia Hospitals (Yazd-Iran) from 2016 to 2020. Age, sex, body mass index (BMI) before surgery, underlying disorders, surgery types (sleeve gastrectomy or gastric bypass), amount of weight loss, leakage, duration time between the end of the surgery, and occurrence of leakage were recorded. The patients were followed up for three months. The patients were observed for the presence of the leakage for two weeks after the operation.

Results: A total of 713 patients were enrolled in the study; 427 underwent sleeve gastrectomy (59.89%), and 286 underwent gastric bypass surgery (40.11%). Of these patients, 43.3% were male. The age of performing the surgery significantly differed between the groups (P-value: 0.031). The gastric bypass group lost more weight than the sleeve gastrectomy group (P-value <0.001). The leakage rate was higher in patients operated on by gastric bypass than those operated on by sleeve gastrectomy (P-value = 0.032). Leakage time significantly differed between the groups (P-value = 0.043).

Conclusion: Bypass gastrectomy has a higher leakage rate than sleeve gastrectomy, but it has a higher effect on weight loss.

Keywords:
  • Anastomotic leak
  • Gastrectomy
  • Gastric bypass
  • Bariatric surgery
  • pdf

How to Cite

Salehnia, H., Rashki Ghalehnoo, S., & Dehghan, A. A. (2025). Comparison of leakage rate after sleeve gastrectomy compared with gastric bypass. Novelty in Biomedicine, 13(2), 75–80. https://doi.org/10.22037/nbm.v13i2.46062
  • ACM
  • ACS
  • APA
  • ABNT
  • Chicago
  • Harvard
  • IEEE
  • MLA
  • Turabian
  • Vancouver
  • Endnote/Zotero/Mendeley (RIS)
  • BibTeX

References

Kuczmarski RJ, Flegal KM. Criteria for definition of overweight in transition: background and recommendations for the United States. The American journal of clinical nutrition. 2000;72(5):1074-81.

Ludwig DS, Ebbeling CB. Weight-loss maintenance—mind over matter? Mass Medical Soc; 2010. p. 2159-61.

Mirhafez SR, Pasdar A, Avan A, Esmaily H, Moezzi A, Mohebati M, et al. Cytokine and growth factor profiling in patients with the metabolic syndrome. British journal of nutrition. 2015;113(12):1911-9.

Rejeski WJ, Bray GA, Chen S-H, Clark JM, Evans M, Hill JO, et al. Aging and physical function in type 2 diabetes: 8 years of an intensive lifestyle intervention. Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences. 2015;70(3):345-53.

Frühbeck G. Bariatric and metabolic surgery: a shift in eligibility and success criteria. Nature Reviews Endocrinology. 2015;11(8):465-77.

Yanovski SZ, Yanovski JA. Long-term drug treatment for obesity: a systematic and clinical review. Jama. 2014;311(1):74-86.

Wolfe BM, Kvach E, Eckel RH. Treatment of obesity: weight loss and bariatric surgery. Circulation research. 2016;118(11):1844-55.

Gagner M, Kemmeter P. Comparison of laparoscopic sleeve gastrectomy leak rates in five staple-line reinforcement options: a systematic review. Surgical endoscopy. 2020;34(1):396-407.

Varela JE, Nguyen NT. Laparoscopic sleeve gastrectomy leads the US utilization of bariatric surgery at academic medical centers. Surgery for Obesity and Related Diseases. 2015;11(5):987-90.

Mason EE, Ito C. Gastric bypass in obesity. Surgical Clinics of North America. 1967;47(6):1345-51.

Aurora AR, Khaitan L, Saber AA. Sleeve gastrectomy and the risk of leak: a systematic analysis of 4,888 patients. Surgical endoscopy. 2012;26(6):1509-15.

Burgos AM, Braghetto I, Csendes A, Maluenda F, Korn O, Yarmuch J, Gutierrez L. Gastric leak after laparoscopic-sleeve gastrectomy for obesity. Obesity surgery. 2009;19(12):1672-7.

Csendes A, Braghetto I, León P, Burgos AM. Management of leaks after laparoscopic sleeve gastrectomy in patients with obesity. Journal of Gastrointestinal Surgery. 2010;14(9):1343-8.

Mui WL-M, Ng EK-W, Tsung BY-S, Lam CC-H, Yung M-Y. Laparoscopic sleeve gastrectomy in ethnic obese Chinese. Obesity surgery. 2008;18(12):1571-4.

Rosenthal RJ, Panel ISGE. International Sleeve Gastrectomy Expert Panel Consensus Statement: best practice guidelines based on experience of> 12,000 cases. Surgery for Obesity and Related Diseases. 2012;8(1):8-19.

Sakran N, Goitein D, Raziel A, Keidar A, Beglaibter N, Grinbaum R, et al. Gastric leaks after sleeve gastrectomy: a multicenter experience with 2,834 patients. Surgical endoscopy. 2013;27(1):240-5.

Berger ER, Clements RH, Morton JM, Huffman KM, Wolfe BM, Nguyen NT, et al. The impact of different surgical techniques on outcomes in laparoscopic sleeve gastrectomies: the first report from the Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program (MBSAQIP). Annals of Surgery. 2016;264(3):464-73.

Cesana G, Cioffi S, Giorgi R, Villa R, Uccelli M, Ciccarese F, et al. Proximal leakage after laparoscopic sleeve gastrectomy: an analysis of preoperative and operative predictors on 1738 consecutive procedures. Obesity Surgery. 2018;28(3):627-35.

D’Ugo S, Gentileschi P, Benavoli D, Cerci M, Gaspari A, Berta RD, et al. Comparative use of different techniques for leak and bleeding prevention during laparoscopic sleeve gastrectomy: a multicenter study. Surgery for Obesity and Related Diseases. 2014;10(3):450-4.

Varban OA, Sheetz KH, Cassidy RB, Stricklen A, Carlin AM, Dimick JB, Finks JF. Evaluating the effect of operative technique on leaks after laparoscopic sleeve gastrectomy: a case-control study. Surgery for Obesity and Related Diseases. 2017;13(4):560-7.

Abou Rached A, Basile M, El Masri H. Gastric leaks post sleeve gastrectomy: review of its prevention and management. World Journal of Gastroenterology: WJG. 2014;20(38):13904.

Gonzalez R, Sarr MG, Smith CD, Baghai M, Kendrick M, Szomstein S, et al. Diagnosis and contemporary management of anastomotic leaks after gastric bypass for obesity. Journal of the American College of Surgeons. 2007;204(1):47-55.

Inabnet III WB, Winegar DA, Sherif B, Sarr MG. Early outcomes of bariatric surgery in patients with metabolic syndrome: an analysis of the bariatric outcomes longitudinal database. Journal of the American College of Surgeons. 2012;214(4):550-6.

Westling A, Öhrvall M, Gustavsson S. Roux-en-Y gastric bypass after previous unsuccessful gastric restrictive surgery. Journal of gastrointestinal surgery. 2002;6(2):206-11.

Frenk SM, Porter KS, Paulozzi L. Prescription opioid analgesic use among adults: United States, 1999-2012: US Department of Health and Human Services, Centers for Disease Control and …; 2015.

Schauer PR, Bhatt DL, Kirwan JP, Wolski K, Aminian A, Brethauer SA, et al. Bariatric surgery versus intensive medical therapy for diabetes—5-year outcomes. N Engl J Med. 2017;376:641-51.

Wang YC, McPherson K, Marsh T, Gortmaker SL, Brown M. Health and economic burden of the projected obesity trends in the USA and the UK. The Lancet. 2011;378(9793):815-25.

El Chaar M, Lundberg P, Stoltzfus J. Thirty-day outcomes of sleeve gastrectomy versus Roux-en-Y gastric bypass: first report based on Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program database. Surgery for Obesity and Related Diseases. 2018;14(5):545-51.

Inaba CS, Koh CY, Sujatha-Bhaskar S, Silva JP, Chen Y, Nguyen DV, Nguyen NT. One-year mortality after contemporary laparoscopic bariatric surgery: an analysis of the bariatric outcomes longitudinal database. Journal of the American College of Surgeons. 2018;226(6):1166-74.

Peterli R, Wölnerhanssen BK, Peters T, Vetter D, Kröll D, Borbély Y, et al. Effect of laparoscopic sleeve gastrectomy vs laparoscopic Roux-en-Y gastric bypass on weight loss in patients with morbid obesity: the SM-BOSS randomized clinical trial. Jama. 2018;319(3):255-65.

Salminen P, Helmiö M, Ovaska J, Juuti A, Leivonen M, Peromaa-Haavisto P, et al. Effect of laparoscopic sleeve gastrectomy vs laparoscopic Roux-en-Y gastric bypass on weight loss at 5 years among patients with morbid obesity: the SLEEVEPASS randomized clinical trial. Jama. 2018;319(3):241-54.

Gadiot RP, Biter LU, Zengerink HJ, de Vos tot Nederveen Cappel R, Elte JWF, Castro Cabezas M, Mannaerts GH. Laparoscopic sleeve gastrectomy with an extensive posterior mobilization: technique and preliminary results. Obesity surgery. 2012;22(2):320-9.

Chen B, Kiriakopoulos A, Tsakayannis D, Wachtel MS, Linos D, Frezza EE. Reinforcement does not necessarily reduce the rate of staple line leaks after sleeve gastrectomy. A review of the literature and clinical experiences. Obesity surgery. 2009;19(2):166-72.

Nabil T, Hussein A, Nabil A. Comparative study between the complications of laparoscopic sleeve gastrectomy and laparoscopic mini-gastric bypass. The Egyptian Journal of Surgery. 2017;36(4):360.

Márquez MF, Ayza MF, Lozano RB, del Mar Rico Morales M, García Díez JM, Poujoulet RB. Gastric leak after laparoscopic sleeve gastrectomy. Obesity surgery. 2010;20(9):1306-11.

Birkmeyer JD, Finks JF, O'reilly A, Oerline M, Carlin AM, Nunn AR, et al. Surgical skill and complication rates after bariatric surgery. New England Journal of Medicine. 2013;369(15):1434-42.

Alizadeh RF, Li S, Inaba C, Penalosa P, Hinojosa MW, Smith BR, et al. Risk factors for gastrointestinal leak after bariatric surgery: MBASQIP analysis. Journal of the american college of surgeons. 2018;227(1):135-41.

Thereaux J, Corigliano N, Poitou C, Oppert J-M, Czernichow S, Bouillot J-L. Comparison of results after one year between sleeve gastrectomy and gastric bypass in patients with BMI≥ 50 kg/m². Surgery for Obesity and Related Diseases. 2015;11(4):785-90.

Schauer PR, Kashyap SR, Wolski K, Brethauer SA, Kirwan JP, Pothier CE, et al. Bariatric surgery versus intensive medical therapy in obese patients with diabetes. New England Journal of Medicine. 2012;366(17):1567-76.

Perathoner A, Weißenbacher A, Sucher R, Laimer E, Pratschke J, Mittermair R. Significant weight loss and rapid resolution of diabetes and dyslipidemia during short-term follow-up after laparoscopic sleeve gastrectomy. Obesity surgery. 2013;23(12):1966-72.

  • Abstract Viewed: 164 times
  • pdf Downloaded: 124 times

Download Statastics

  • Linkedin
  • Twitter
  • Facebook
  • Google Plus
  • Telegram

Developed By

Open Journal Systems

Information

  • For Readers
  • For Authors
  • For Librarians
  • Home
  • Archives
  • Submissions
  • About the Journal
  • Editorial Team
  • Contact
Powered by OJSPlus