Inadvertent Transfusion of Two Incompatible Blood Units: A Case Report
Novelty in Biomedicine,
Vol. 11 No. 2 (2023),
24 June 2023
,
Page 77- 80
https://doi.org/10.22037/nbm.v11i3.39844
Abstract
Background: An incompatible blood transfusion may lead to hemolytic transfusion reactions and severe complications such as intravascular hemolysis, multiorgan failure, and even death. Prevention, early diagnosis, and treatments have the main roles to decrease transfusion complications.
Cases Report: We present a case of a 43-year-old woman with a history of mandibular malignancy and facial reconstruction surgery who needed to blood transfusion due to a hemorrhage around her tracheostomy, and inadvertently 2 units of incompatible blood were transfused. The errors conduce to this issue and consideration to prevent and manage incompatible blood transfusions are discussed.
Conclusion: This case showed that an effective technique for recognizing and avoiding transfusion mistakes is staff awareness of the potential errors at the bedside and in the laboratory. Furthermore, patients’ immunological status, early detection, and recognition of blood transfusion manifestation are critical factors for early diagnosis and treatment.
- Blood transfusion
- ABO incompatibility
- Coomb's test
- hematuria
- Hemolytic transfusion reaction
How to Cite
References
Rudlof B, Just B, Deitenbeck R, Ehmann T. Mismatched transfusion of 8 AB0-incompatible units of packed red blood cells in a patient with acute intermittent porphyria. Saudi J Anaesth. 2011;5(1):101–4.
Webster BH. Clinical Presentation of Haemolytic Transfusion Reactions. Vol. 8, Anaesth Intens Care. 1980.
Weinstock C, Möhle R, Dorn C, Weisel K, Höchsmann B, Schrezenmeier H, et al. Successful use of eculizumab for treatment of an acute hemolytic reaction after ABO-incompatible red blood cell transfusion. 2014.
Nuttall GA, Stubbs JR, Oliver WC. Transfusion errors: Causes, incidence, and strategies for prevention. Curr Opin Anaesthesiol. 2014;27(6):657–9.
Strobel E. Hemolytic Transfusion Reactions. 2008; Available from: www.karger.com
Janatpour KA, Kalmin ND, Jensen HM, Holland P V. Clinical outcomes of ABO-incompatible RBC transfusions. Am J Clin Pathol. 2008;129(2):276–81.
Namikawa A, Shibuya Y, Ouchi H, Takahashi H, Furuto Y. A case of ABO-incompatible blood transfusion treated by plasma exchange therapy and continuous hemodiafiltration. CEN Case Reports [Internet]. 2018;7(1):114–20.
Gupta S, Ahern K, Nakhl F, Forte F. Clinical Study Clinical Usefulness of Haptoglobin Levels to Evaluate Hemolysis in Recently Transfused Patients. Adv Hematol. 2011;2011.
Prevention and treatment of heme pigment-induced acute kidney injury (including rhabdomyolysis) - UpToDate [Internet]. [cited 2022 May 29]. Available from: https://www.uptodate.com/contents/prevention-and-treatment-of-heme-pigment-induced-acute-kidney-injury-including-rhabdomyolysis.
- Abstract Viewed: 92 times
- pdf Downloaded: 69 times