Prevalence of Pulmonary Tuberculosis, Failure of Treatment, and its Related Factors in Kashan During 2004-2017
Novelty in Biomedicine,
Vol. 11 No. 1 (2023),
20 Esfand 2023
,
Page 1-8
https://doi.org/10.22037/nbm.v11i1.39491
Abstract
Background: Mycobacterium tuberculosis affects the lungs in 85% of all cases and the remaining 15% through extra pulmonary affecting other parts of the body such as lymph nodes, pleura, and the genitourinary system. This study aimed to investigate extra-pulmonary tuberculosis (TB) associated factors, failure of treatment, and trends between 2004-2017 in Kashan, Iran.
Materials and Methods: This study was conducted during 2004-2017 on newly registered extrapulmonary tuberculosis patients referred to TB Referral Center in Isfahan province, Kashan city, Iran. Information (demographic characteristics, related factors of the disease, and treatment status) of 197 extrapulmonary tuberculosis (EPTB) patients was extracted from Medical case records.
Results: In total, 527 cases of Tuberculosis were reported, of which, 159 (30.17%) were confirmed
extrapulmonary TB. Eighty-five (53.5%) and 74 (46.5%) were male and female, respectively. Also, 74
(46.5%), and 84 (53.5%) of EPTB were from Iran, and Afghanistan immigrants, respectively. The average age of patients was 41.9±2.18. Among underlying diseases in extrapulmonary TB positive, diabetes mellitus (DM) was predominant with a prevalence of 31 (19.5%), while, 128 (80.5%) cases did not show any underlying disease. Most of the patients were in the age group (21-40 years) with a frequency of 60 (37.7%), and the lowest of patients belonged to the age group (>80 years) with a frequency of 9 (5.7%). No correlation was found between related factors and infection with EPTB (p> 0.05).
Conclusion: Our findings showed that the prevalence of EPTB in Kashan was relatively high, but, a relative decrease was shown during 2004-2017, which with preventative measures can be reduced the prevalence.
- Epidemiology, Tuberculosis, Prevalence
How to Cite
References
Amiri MJ, Karami P, Chichaklu AH, Jangan EH, Amiri MJ, Owrang M, et al. Identification and Isolation of Mycobacterium tuberculosis from Iranian Patients with Recurrent TB using Different Staining Methods. J Res Med Dent Sci. 2018;6(2):409-14.
Ashna H, Kaffash A, Khaledi A, Ghazvini K. Mutations of rpob Gene Associated with Rifampin Resistance among Mycobacterium Tuberculosis Isolated in Tuberculosis Regional Reference Laboratory in Northeast of Iran during 2015-2016. Ethiopian Journal of Health Sciences. 2018;28(3):299-304.
Amiri MRJ, Siami R, Khaledi A. Tuberculosis Status and Coinfection of Pulmonary Fungal Infections in Patients Referred to Reference Laboratory of Health Centers Ghaemshahr City during 2007–2017. Ethiopian journal of health sciences. 2018;28(6):683.
Organization WH. Global tuberculosis report 2018. Geneva: World Health Organization; 2018. Licence: CC BY-NC-SA 3.0 IGO. WHO/CDS/TB/2018.20. Available from: http://apps. who. int/iris/bitstream …; 2019.
Nasehi M, Mirhaghaani L. Guideline for National Tuberculosis Control. Tehran: Ministry of Health and Medical Education. 2014.
Kingkaew N, Sangtong B, Amnuaiphon W, Jongpaibulpatana J, Mankatittham W, Akksilp S, et al. HIV-associated extrapulmonary tuberculosis in Thailand: epidemiology and risk factors for death. International Journal of Infectious Diseases. 2009;13(6):722-9.
Aaron L, Saadoun D, Calatroni I, Launay O, Memain N, Vincent V, et al. Tuberculosis in HIV-infected patients: a comprehensive review. Clinical microbiology and infection. 2004;10(5):388-98.
Pollett S, Banner P, O’Sullivan MV, Ralph AP. Epidemiology, diagnosis and management of extra-pulmonary tuberculosis in a low-prevalence country: a four year retrospective study in an Australian Tertiary Infectious Diseases Unit. PloS one. 2016;11(3):e0149372.
Barry C, Waring J, Stapledon R, Konstantinos A. Tuberculosis notifications in Australia, 2008 and 2009. Communicable diseases intelligence quarterly report. 2012;36(1):82.
Roberts-Witteveen AR, Christensen A, McAnulty JM. EpiReview: tuberculosis in NSW, 2008. New South Wales public health bulletin. 2010;21(8):174-82.
Hussein MM, Mooij JM, Roujouleh H, editors. Tuberculosis and chronic renal disease. Seminars in dialysis; 2003: Wiley Online Library.
Yoon HJ, Song YG, Kim JM, Chang KH, Choi JP, Park WI. Clinical manifestations and diagnosis of extrapulmonary tuberculosis. 2004.
Tay E. Innovative use of tuberculosis surveillance data to inform practice & policy. Advances in Tuberculosis: Australian and Regional Perspectives. 2013:14-5.
Porkert MT, Sotir M, Parrott-Moore P, Blumberg HM. Tuberculous meningitis at a large inner-city medical center. The American journal of the medical sciences. 1997;313(6):325-31.
Arsang-Jang S, Mansourian M, Amani F, Jafari-Koshki T. Epidemiologic trend of smear-positive, smear-negative, extra pulmonary and relapse of tuberculosis in iran (2001-2015); a repeated cross-sectional study. Journal of research in health sciences. 2017;17(2).
Siroka A, Ponce NA, Lönnroth K. Association between spending on social protection and tuberculosis burden: a global analysis. The Lancet Infectious Diseases. 2016;16(4):473-9.
Zumla A, George A, Sharma V, Herbert RHN, Oxley A, Oliver M. The WHO 2014 global tuberculosis report—further to go. The Lancet Global Health. 2015;3(1):e10-e2.
Rafiee S, Besharat S, Jabbari A, Golalipour F, Nasermoaadeli A. Epidemiology of tuberculosis in northeast of Iran: a population-based study. Iranian Journal of Medical Sciences. 2009;34(3):193-7.
Qian X, Nguyen DT, Lyu J, Albers AE, Bi X, Graviss EA. Risk factors for extrapulmonary dissemination of tuberculosis and associated mortality during treatment for extrapulmonary tuberculosis. Emerging microbes & infections. 2018;7(1):1-14.
Yang Z, Kong Y, Wilson F, Foxman B, Fowler AH, Marrs CF, et al. Identification of risk factors for extrapulmonary tuberculosis. Clinical infectious diseases. 2004;38(2):199-205.
Clegg LX, Hankey BF, Tiwari R, Feuer EJ, Edwards BK. Estimating average annual per cent change in trend analysis. Statistics in medicine. 2009;28(29):3670-82.
Organization WH. Global tuberculosis report 2013: World Health Organization; 2013.
Peto HM, Pratt RH, Harrington TA, LoBue PA, Armstrong LR. Epidemiology of extrapulmonary tuberculosis in the United States, 1993–2006. Clinical Infectious Diseases. 2009;49(9):1350-7.
Standards D, Adults CoTi, Children. This official statement of the American Thoracic Society and the Centers for Disease Control and Prevention was adopted by the ATS Board of Directors, July 1999. This statement was endorsed by the Council of the Infectious Disease Society of America, September 1999. Am J Respir Crit Care Med. 2000;161(4 Pt 1):1376-95.
Gomes T, Reis-Santos B, Bertolde A, Johnson JL, Riley LW, Maciel EL. Epidemiology of extrapulmonary tuberculosis in Brazil: a hierarchical model. BMC infectious diseases. 2014;14(1):9.
Sanches I, Carvalho A, Duarte R. Who are the patients with extrapulmonary tuberculosis? Revista Portuguesa de Pneumologia (English Edition). 2015;21(2):90-3.
Yahyavi M, Delavari A, Karimi Z, Falsafi-Zadeh S, Samieifar S, Abbasi F, et al. Epidemiological Survey of Extrapulmonary Tuberculosis in Baghmalek City of Khuzestan Province in Iran (2007-2011). Jundishapur Journal of Chronic Disease Care. 2015;4(2).
Gaifer Z. Epidemiology of extrapulmonary and disseminated tuberculosis in a tertiary care center in Oman. International journal of mycobacteriology. 2017;6(2):162.
Organization WH. Tuberculosis control in the South-East Asia region: annual TB report 2014. 2014.
Al-Otaibi F, El Hazmi MM. Extra-pulmonary tuberculosis in Saudi Arabia. Indian Journal of Pathology and Microbiology. 2010;53(2):227.
Ghaffari-Fam S, Hosseini SR, Heydari H, Vaseghi-Amiri R, Daemi A, Nikbakht HA. Epidemiological patterns of Tuberculosis disease in the Babol, Iran. Analyt Res Clin Med. 2015;3(3):146-9.
Adada H, Valley M, Nour S, Mehta J, Byrd R, Anderson J, et al. Epidemiology of extra-pulmonary tuberculosis in the United States: high rates persist in the post-HIV era. The International Journal of Tuberculosis and Lung Disease. 2014;18(12):1516-21.
Kruijshaar ME, Abubakar I. Increase in extrapulmonary tuberculosis in England and Wales 1999–2006. Thorax. 2009;64(12):1090-5.
Sandgren A, Hollo V, Van der Werf M. Extrapulmonary tuberculosis in the European Union and European economic area, 2002 to 2011. Eurosurveillance. 2013;18(12):20431.
Mohammadien H, Alkhayat K, Hamed A, Shaaban M. Patterns, trends and treatment outcomes of extra-pulmonary tuberculosis in Sohag, Upper Egypt. Egyptian Journal of Chest Diseases and Tuberculosis. 2017;66(2):313-6.
García-Rodríguez JF, Álvarez-Díaz H, Lorenzo-García MV, Mariño-Callejo A, Fernández-Rial Á, Sesma-Sánchez P. Extrapulmonary tuberculosis: epidemiology and risk factors. Enfermedades infecciosas y microbiologia clinica. 2011;29(7):502-9.
Lin C-Y, Chen T-C, Lu P-L, Lai C-C, Yang Y-H, Lin W-R, et al. Effects of gender and age on development of concurrent extrapulmonary tuberculosis in patients with pulmonary tuberculosis: a population based study. PLoS One. 2013;8(5):e63936.
Pang Y, An J, Shu W, Huo F, Chu N, Gao M, et al. Epidemiology of Extrapulmonary Tuberculosis among Inpatients, China, 2008–2017. Emerging infectious diseases. 2019;25(3):457.
Dayalan MR, Johnson HD, Kasinathan G, Pillai N. Unusual Presentations of Tuberculosis: A Case Series. Open Access Library Journal. 2016;3(03):1.
Lin J, Lai C, Chen Y, Lee S, Tsai S, Huang C, et al. Risk factors for extra-pulmonary tuberculosis compared to pulmonary tuberculosis. The International Journal of Tuberculosis and Lung Disease. 2009;13(5):620-5.
Magee M, Foote M, Ray S, Gandhi N, Kempker R. Diabetes mellitus and extrapulmonary tuberculosis: site distribution and risk of mortality. Epidemiology & Infection. 2016;144(10):2209-16.
Babamahmoodi F, Alikhani A, Yazdani Charati J, Ghovvati A, Ahangarkani F, Delavarian L, et al. Clinical epidemiology and paraclinical findings in tuberculosis patients in north of Iran. BioMed research international. 2015;2015.
Bialvaei AZ, Asgharzadeh M, Aghazadeh M, Nourazarian M, Kafil HS. Challenges of Tuberculosis in Iran. Jundishapur Journal of Microbiology. 2017;10(3).
Mayor S. Report on health of migrants to UK shows high risk of TB and HIV. British Medical Journal Publishing Group; 2006.
Minetti A, Camelique O, Hsa Thaw K, Thi S, Swaddiwudhipong W, Hewison C, et al. Tuberculosis treatment in a refugee and migrant population: 20 years of experience on the Thai-Burmese border. The International Journal of Tuberculosis and Lung Disease. 2010;14(12):1589-95.
Gai RT, Xu L, Song P, Huang Y. The rural-to-urban migrant population in China: gloomy prospects for tuberculosis control. Bioscience trends. 2011;5(6):226-30.
Okita K. Gender and literacy: factors related to diagnostic delay and unsuccessful treatment of tuberculosis in the mountainous area of Yemen. The International Journal of Tuberculosis and Lung Disease. 2005;9(6):680-5.
Marais B, Hesseling A, Cotton M. Poverty and tuberculosis: is it truly a simple inverse linear correlation? European Respiratory Journal. 2009;33(4):943-4.
Prevention OoD, Health HPUDo, Services H. National action plan to improve health literacy: US Department of Health & Human Services; 2010.
Tekle B, Mariam D, Ali A. Defaulting from DOTS and its determinants in three districts of Arsi Zone in Ethiopia. The International Journal of Tuberculosis and Lung Disease. 2002;6(7):573-9.
Chandir S, Hussain H, Salahuddin N, Amir M, Ali F, Lotia I, et al. Extrapulmonary tuberculosis: a retrospective review of 194 cases at a tertiary care hospital in Karachi, Pakistan. JPMA The Journal of the Pakistan Medical Association. 2010;60(2):105.
Ravikumar P, Priyadarshini Bai G. A study of extra-pulmonary tuberculosis and its outcome. International Journal of Advances in Medicine. 2017;4(1):209.
Chandrasekaran V, Gopi P, Subramani R, Thomas A, Jaggarajamma K, Narayanan P. Default during the intensive phase of treatment under DOTS programme. Indian Journal of Tuberculosis. 2005;52(4):197-202.
Diallo A, Dahourou DL, Tassembedo S, Sawadogo R, Meda N. Factors associated with tuberculosis treatment failure in the Central East Health region of Burkina Faso. The Pan African Medical Journal. 2018;30.
Sawadogo B, Tint KS, Tshimanga M, Kuonza L, Ouedraogo L. Risk factors for tuberculosis treatment failure among pulmonary tuberculosis patients in four health regions of Burkina Faso, 2009: case control study. Pan African medical journal. 2015;21(1).
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