ISSN: 2345-3346
Summer 2022
Vol. 10 No. 3 (2022)
A systematic review and meta-analysis of Latent tuberculosis infection in Health care workers in Iran Latent tuberculosis infection in HCWs
Novelty in Biomedicine,
Vol. 10 No. 3 (2022),
,
Page 192-198
https://doi.org/10.22037/nbm.v10i3.37526
Abstract
Background: Health care workers (HCWs) are more likely to get latent tuberculosis infection (LTBI) because of
the direct contact they may have with patients and carriers. Therefore, this study aimed to assess the prevalence
of LTBI in HCWs.
Materials and Methods: In the present study, we searched from 1st 2010 to the end of 2021 in various databases
such as; PubMed, Scopus, Web of sciences, and Google Scholar for studies presented LTBI in HCWS. After
applying inclusion and exclusion criteria and quality assessment, obtained data were analyzed by Comprehensive
Meta-analysis (CMV) software.
Results: In total, 22 studies met the eligibility criteria to include in the present systematic review and metaanalysis. The combined prevalence of LTBI was reported by 25.9% (95% CI: 19.3-33.7). No publication bias
was seen among studies included based on Eger’s regression test (p=0.04).
Conclusion: Our study showed a high prevalence of LTBI in HCWs. Therefore, periodical screening of HCWs
with Suitable tests is essential to prevent this high prevalence. According to the results of this systematic
review and meta-analysis, the rate of LTBI in Iranian HCWs is high. Therefore, periodical screening and
diagnostic tests such as TST are necessary for the timely diagnosis and treatment of these individuals to prevent changing LTBI to an active form of tuberculosis.
- Health care worker, Latent tuberculosis infection, Patient
How to Cite
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