A Comparison of Postoperative Delirium in Children Undergoing Elective Herniorrhaphy Following General Anesthesia with Sevoflurane and Isoflurane
Iranian Journal of Pediatric Surgery,
Vol. 12 No. 1 (2026),
20 Ordibehesht 2026
,
Page 10-24
https://doi.org/10.22037/irjps.v12i1.50761
Abstract
Abstract
Introduction: Postoperative delirium and agitation is a distressing event that occurs in most children. This study aimed to compare of postoperative delirium in children undergoing elective herniorrhaphy following general anesthesia by sevoflurane and isoflurane.
Materials and Methods: In this double-blind randomized clinical trial, 50 children aged 2 to 6 years; candidates for inguinal herniorrhaphy were divided into two groups of general anesthesia induced by sevoflurane and isoflurane. Anesthesia was induced by administering 5-7 mg / kg sodium thiopental and 0.5 mg / kg atracurium. They were monitored every 10 minutes to 30 minutes for postoperative delirium (POD) using Pediatric Anesthesia Emergence Delirium (PAED) scale.
Results: The POD frequency was in the isoflurane and sevoflurane groups 1 (4%) and 18 (72%), respectively and this difference was significant between two groups (P=0.001). According to PAED, the POD severity in isoflurane group was less than sevoflurane group at minute 10 (P = 0.001). Also, there was a significant difference between the two groups in terms of POD severity at minute 20 (P= 0.001). The highest POD severity was seen in the isoflurane group at minute 30 (P =0.001).
Conclusion: The results of the present study showed that the use of sevoflurane in the anesthesia maintenance phase for children less than 6 years of age leads to higher POD incidence as compared to isoflurane
- Sevoflurane
- Isoflurane
- Agitation
- Delirium
- Herniorrhaphy
- General anesthesia
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References
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