Comparison of Bilateral Infraorbital Nerve Block with Lidocaine Hydrochloride (Xylocaine) Or Bupivacaine Hydrochloride (Marcaine) With Intravenous Pethidine for Postoperative Pain Management of Pediatric Patients of Cleft Lip Surgery (Cheiloplasty): A Prospective Double Blind Randomized Clinical Trial
Iranian Journal of Pediatric Surgery,
Vol. 10 No. 1 (2024),
4 April 2024
,
Page 88-97
https://doi.org/10.22037/irjps.v10i1.44632
Abstract
Introduction: Post-operative pain relief is one of the major practices in anesthesiology. The different pharmacokinetic and sensitivity of children to different classes of anesthetics drugs, especially opioids, make the clinical judgment of pediatric anesthesiologist harder.
Materials and Methods: After getting ethical approval, all the patients who underwent surgery for cleft lip surgery with pain management at Mofid Children's Hospital were contacted, and in case of any long-term complications, parents were invited to visit the hospital.
Results: The average duration of analgesia in the X, M and P group were 18.48± 2.45, 17.62± 2.96, and 17.56± 3.16 hours, respectively. The duration of analgesia in the group X was superior to the other groups; however, there was not any meaningful different between the duration of analgesia between the 3 groups (p>0.05).
Conclusion: the present double-blind clinical trial disclosed that the preoperative bilateral infraorbital nerve block induced an anesthetic effect prolonged as the duration induced by the opioid infusion.
- cleft lip
- inferior orbital block
- pain managment
- bupivacaien
- lidocaien
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References
Mane RS, Sanikop CS, Dhulkhed VK, et al: Comparison of Bupivacaine Alone and in Combination with Fentanyl or Pethidine for Bilateral infraorbital Nerve Block for Postoperative Analgesia in Paediatric Patients for Cleft Lip Repair: A Prospective Randomized Double-Blind Study. J Anaesthesiol Clin Pharmacol. 2011;27(1):23-6.
Gaonkar V, Daftary SR: Comparison of preoperative infraorbital block with peri-incisional infiltration for postoperative pain relief in cleft lip surgeries. Indian Journal of Plastic Surgery. 2004;37(02):105-9.
Countryman NB, Hanke CW: Practical Review of Peripheral Nerve Blocks in Dermatologic Surgery of the Face. Current Dermatology Reports. 2012;1(2):49-54.
Reena, Bandyopadhyay KH, Paul A: Postoperative analgesia for cleft lip and palate repair in children. J Anaesthesiol Clin Pharmacol. 2016;32(1):5-11.
Doyle E, Hudson I: Anaesthesia for primary repair of cleft lip and cleft palate: a review of 244 procedures. Pediatric Anesthesia. 1992;2(2):139-45.
Hatch D: Analgesia in the neonate. British medical journal (Clinical research ed). 1987;294(6577):920.
Yaster M: Analgesia and anesthesia in neonates. The Journal of pediatrics. 1987;111(3):394-6.
Yao F-SF, Fontes ML, Malhotra V: Yao & Artusio's anesthesiology: Problem-oriented patient management: Lippincott Williams & Wilkins; 2008.
Krechel SW, Bildner J: CRIES: a new neonatal postoperative pain measurement score. Initial testing of validity and reliability. Pediatric Anesthesia. 1995;5(1):53-61.
Goodyear MD, Krleza-Jeric K, Lemmens T: The Declaration of Helsinki. Bmj. 2007;335(7621):624-5.
Brislin RP, Rose JB: Pediatric acute pain management. Anesthesiology Clinics of North America. 2005;23(4):789-814.
Purcell‐Jones G, Dormon F, Sumner E: The use of opioids in neonates. A retrospective study of 933 cases. Anaesthesia. 1987;42(12):1316-20.
Markakis DA: Regional anesthesia in pediatrics. Anesthesiology Clinics of North America. 2000;18(2):355-81.
Armstrong P, Morton C, Nimmo A: Pethidine has a local anaesthetic action on peripheral nerves in vivo: addition to prilocaine 0.25% for intravenous regional anaesthesia in volunteers. Anaesthesia. 1993;48(5):382-6.
Bazin J, Massoni C, Bruelle P, et al: The addition of opioids to local anaesthetics in brachial plexus block: the comparative effects of morphine, buprenorphine and sufentanil. Anaesthesia. 1997;52(9):858-62.
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