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Vol. 9 No. 1 (2023)

May 2023

Ovarian Juvenile Granulosa Cell Tumor in A 2.5 Years-Old Girl: The Importance of Early Diagnosis

  • Malak Boughdir
  • Aida daib
  • Rabiaa Ben abdallah
  • Fatma Chebab
  • Sameh Tlili
  • Youssef hellel
  • nejib kaabar

Iranian Journal of Pediatric Surgery, Vol. 9 No. 1 (2023), 11 May 2023 , Page 120-125
https://doi.org/10.22037/irjps.v9i1.35714 Published: 2023-05-20

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Abstract

Juvenile granulosa tumor is a rare tumor in infant. The diagnosis should be discussed in any ovarian tumor of children, especially in front of the early signs of puberty. The prognosis of granulosa cell tumors remains good. The main prognostic factor is the stage of local extension. Early diagnosis at early signs of puberty is an important prognostic factor. We describe the case of a girl aged 2 years and 5 months who presented signs of early puberty. The diagnosis was a secreting ovarian tumor but was very large at that time. We focus by this observation on the value of early diagnosis of this tumor type which remains a key prognostic factor.

Keywords:
  • ovary ; juvenile granulosa tumor ; early puberty ; infant
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How to Cite

Boughdir, M., daib, A., Ben abdallah, R., Chebab, F., Tlili, S., hellel, Y., & kaabar, nejib. (2023). Ovarian Juvenile Granulosa Cell Tumor in A 2.5 Years-Old Girl: The Importance of Early Diagnosis. Iranian Journal of Pediatric Surgery, 9(1), 120–125. https://doi.org/10.22037/irjps.v9i1.35714
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References

Hashemipour M, Moaddab MH, Nazem M, et al; Granulosa cell tumor in a six-year-old girl presented as precocious puberty. Journal of Research in Medical Sciences: The Official Journal of Isfahan University of Medical Sciences. 2010 Jul;15(4):240.

Wang Y, Wang W, Xu C, et al; Childhood ovarian juvenile granulosa cell tumor: a retrospective study with 3 cases including clinical features, pathologic results, and therapies. Journal of Pediatric Hematology/Oncology. 2011 Apr 1;33(3):241-5.

Nishida M, Jimi S, Haji M, et al; Juvenile granulosa cell tumor in association with a high serum inhibin level. Gynecologic oncology. 1991 Jan 1;40(1):90-4.

Bouffet E, Basset T, Chetail N, et al; Juvenile granulosa cell tumor of the ovary in infants: a clinicopathologic study of three cases and review of the literature. Journal of pediatric surgery. 1997 May 1;32(5):762-5.

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