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  3. Vol. 10 No. 1 (2026): In Press
  4. Original Articles

Vol. 10 No. 1 (2026)

January 2026

Evaluating the Effect of Hypertension on Visual Pathway using Visual Evoked Potential

  • Faezeh Sahbaei
  • Seyed Mohammad Masoud Shushtarian

Journal of Ophthalmic and Optometric Sciences, Vol. 10 No. 1 (2026), 1 January 2026
https://doi.org/10.22037/joos.v10i1.53662 Published: 2025-12-22

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Abstract

Purpose: Blood Pressure (BP) is the pressure of circulating blood against the walls of blood vessels, and high blood pressure or hypertension is the condition in which the blood pressure is too high. Hypertension may affect different body organs. The visual system, mainly the visual pathway, may be affected by hypertension. The aim of the present study is to find out the possible effect of hypertension on the visual pathway using visual evoked potential.

Materials and Methods: Twenty-five patients (50 eyes) from 11 male and 14 female patients suffering from hypertension, were selected for the purpose of the present study. The patients were 47-67 years old. The patients had normal Best Corrected Visual Acuity (BCVA). Visual evoked potential (VEP) was tested including Latency (msec) and amplitude (µv) of VEP P100 peak were measured in the patients. The same procedure was done for 25 patients (50 eyes) from a control group with ordinary blood pressure, matched in terms of age, sex and BCVA. The results obtained in the two groups were compared to look for possible differences.

Results: There was a statistically significant difference between the case and control groups as far as latency of VEP P100 was concerned (P < 0.001), whereas no statistically significant difference was observed in amplitude between the case and control groups (P = 0.78).

Conclusion: Hypertension might affect the visual pathway of patients, which might be observed using VEP.

Keywords:
  • Hypertension
  • Visual Pathway
  • Visual Evoked Potential
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How to Cite

Sahbaei , F., & Shushtarian, S. M. M. (2025). Evaluating the Effect of Hypertension on Visual Pathway using Visual Evoked Potential. Journal of Ophthalmic and Optometric Sciences, 10(1). https://doi.org/10.22037/joos.v10i1.53662
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References

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2- Kearney PM, Whelton M, Reynolds K, Muntner P, Whelton PK, He J. Global burden of hypertension: analysis of worldwide data. Lancet. 2005 Jan 15-21;365(9455):217-23.

3- Rezaianzadeh A, Johari MG, Baeradeh N, Seif M, Hosseini SV. Sex differences in hypertension incidence and risk factors: a population-based cohort study in Southern Iran. BMC Public Health. 2024 Dec 23;24(1):3575.

4- Mensah GA. Hypertension and Target Organ Damage: Don't Believe Everything You Think! Ethn Dis. 2016 Jul 21;26(3):275-8.

5- Hamzavi F, Fatemian N, Shushtarian SM. Visual Pathway Dysfunction in Myasthenia Gravis Assessed by Pattern Reversal Visual Evoked Potentials: A Case–Control Study. Journal of Ophthalmic and Optometric Sciences. 2025;9(3):30-5.

6- Eslampoor N, Pharm D, Shushtarian SM, Shiehmorteza M. Evaluating the Effect of Botulinum Toxin on Visual Pathway Measured by Visual Evoked Potential Using Flash and Pattern Reversal Checkerboard Stimulation Techniques. Journal of Ophthalmic and Optometric Sciences. 2023;7(3):1-4.

7- Shanmugam SL, Sivagangailakshmi V. Evaluation of Visual Evoked Potential among Hypertensive and Normotensive Individuals. National Journal of Physiology. 2026 Jul 31;12(2):29-32.

8- Achuthan A, Girija S. Pattern visual evoked potential in newly diagnosed hypertensive individuals. Int J Res Med Sci. 2015; 3:3614-9.

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