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  3. Vol. 7 No. 4 (2023): Autumn
  4. Original Articles

Vol. 7 No. 4 (2023)

September 2023

Visual and Refractive Outcomes after Topographic-Guided Customized Ablation Photorefractive Keratectomy in Keratoconic Eyes

  • Hossein Mohammad Rabei
  • Zahra Ghadyani
  • Siamak Delfaza
  • Sepehr Feizi

Journal of Ophthalmic and Optometric Sciences, Vol. 7 No. 4 (2023), 23 September 2023 , Page 7-11
https://doi.org/10.22037/joos.v7i4.47444 Published: 2023-09-23

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Abstract

Purpose: To investigate the visual and refractive outcomes of topographic-guided customized ablation treatment (T-CAT) photorefractive keratectomy (PRK) combined with iris registration and the use of  mitomycin C among patients who have undergone corneal transplantation.
Patients and Methods: This cross-sectional study was conducted on 18 eyes of 14 patients with keratoconus over a 2-year period at Torfeh Eye Hospital, Tehran, Iran. Of these patients, 11 patients were male and 3 patients were female. All participants had previously undergone penetrating keratoplasty (PKP) or deep anterior lamellar keratoplasty (DALK) and subsequently underwent T- CAT PRK surgery with 0.02 % mitomycin C to correct residual refractive errors due to intolerance or reluctance to wear glasses or contact lenses. Pre- and post- T-CAT PRK surgery assessments included uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA), cylindrical and spherical lens measurements, spherical equivalent, and corneal opacity in the transplanted cornea.
Results: The mean postoperative spherical equivalent decreased from 4.27 ± 2.28 D to 1.48 ± 1.39 D, a statistically significant reduction (P = 0.001). The improvements in UCVA, BCVA, and spherocylinder levels were also statistically significant during the follow-up periods after PRK.
Conclusion: The present study suggest that T-CAT PRK combined with iris registration and the use of  mitomycin C intraoperatively in keratoconus patients who have undergone corneal transplantation can effectively treat spherical astigmatism. This approach significantly reduced refractive errors and improved visual and refractive parameters.

Keywords:
  • Keratoconus
  • Keratoplasty
  • Refractive Error
  • Topography
  • Photorefractive Keratectomy
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How to Cite

Mohammad Rabei, H., Ghadyani , Z., Delfaza , S., & Feizi, S. (2023). Visual and Refractive Outcomes after Topographic-Guided Customized Ablation Photorefractive Keratectomy in Keratoconic Eyes. Journal of Ophthalmic and Optometric Sciences, 7(4), 7–11. https://doi.org/10.22037/joos.v7i4.47444
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References

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