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Vol. 3 No. 2 (2019)

April 2019

The Use of Subconjunctival Erythropoietin Injection to Treat Avascular Bleb after Trabeculectomy: A Case Report

  • Maryam Yadgari
  • Iman Ansari
  • Kiana Hassanpour

Journal of Ophthalmic and Optometric Sciences, Vol. 3 No. 2 (2019), 6 April 2019 , Page 33-36
https://doi.org/10.22037/joos.v3i2.33974 Published: 2019-04-06

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Abstract

Purpose: To report a patient with avascular bleb after trabeculectomy who showed promising results after subconjunctival erythropoietin injection.

Case Report: A 45-year-old woman with the diagnosis of primary open-angle glaucoma and history of trabeculectomy three years prior was admitted to our center. The corrected distance visual acuity (CDVA) was 20/20 in both eyes. Her ocular examination revealed an avascular and cystic bleb in the right eye. Seidel test was negative while bleb sweating was observed after fluorescein staining of the bleb area. Intraocular pressure (IOP) was 5 mmHg in the right eye. Erythropoietin (2000 unit in 0.1 ml) was injected subconjuctivally around the bleb area in the temporal quadrant. Six weeks after the injection, the bleb area just superior to the conjunctiva showed an increased fibrosis formation while the IOP remained the same as before injection.

 

Keywords:
  • Erythropoietin; Bleb; Leakage; Glaucoma; Open-angle.
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How to Cite

Yadgari, M., Ansari , I. ., & Hassanpour, K. . . (2019). The Use of Subconjunctival Erythropoietin Injection to Treat Avascular Bleb after Trabeculectomy: A Case Report. Journal of Ophthalmic and Optometric Sciences, 3(2), 33–36. https://doi.org/10.22037/joos.v3i2.33974
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References

1. Leung DY, Tham CC. Management of bleb complications after trabeculectomy. Semin Ophthalmol. 2013;28(3):144-56.

2. Abri Aghdam K, Soltan Sanjari M, Ghasemi Falavarjani K. Erythropoietin in ophthalmology: A literature review. J Curr Ophthalmol. 2016;28(1):5-11.

3. Hernández CC, Burgos CF, Gajardo AH, Silva-Grecchi T, Gavilan J, Toledo JR,et al. Neuroprotective effects of erythropoietin on neurodegenerative and ischemic brain diseases: the role of erythropoietin receptor. Neural Regen Res. 2017;12(9):1381-9.

4. Hamed S, Ullmann Y, Masoud M, Hellou E, Khamaysi Z, Teot L. Topical erythropoietin promotes wound repair in diabetic rats. J Invest Dermatol. 2010;130(1):287-94.

5. Resende AP, Rosolen SG, Nunes T, São Braz B, Delgado E. Functional and Structural Effects of Erythropoietin Subconjunctival Administration in Glaucomatous Animals. Biomed Hub. 2018;3(2):1-11.

6. Acar U, Kucuk B, Sevinc MK, Aykas S, Erdurmus M, Sobaci G. Intravitreal erythropoietin injection in late-stage optic neuropathy: a safety study on human. Int Ophthalmol. 2018;38(3):1021-5.
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