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Vol. 1 No. 1 (2016)

Mehr 2016

A Rare Case of Concurrent Granular Corneal Dystrophy and Keratoconus

  • Mohsen Gohari
  • Ahmad Shojaei
  • Sanaz Rahmatkha
  • Heidar Salehi

Journal of Ophthalmic and Optometric Sciences, Vol. 1 No. 1 (2016), 6 Mehr 2016 , Page 37-41
https://doi.org/10.22037/joos.v1i1.16496 Published: 2017-09-24

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Abstract

A 23-year-old female presented with progressive bilateral visual loss for the past 5 years. The patient had no history of systemic disease, surgery or medications. Complete ophthalmologic examination and topography were performed. On ophthalmic examination, uncorrected visual acuity was 20/30 in the right eye and 20/50 in the left eye. Both corneas appeared hazy on gross examination. On slit-lamp biomicroscopy, few well circumscribed gray white discrete granular deposits in the central corneal stroma of both eyes were observed. Both corneas were thin and bulging. Corneal topography showed a pattern consistent with keratoconus. The patient was clinically diagnosed as a case of concurrent granular dystrophy and keratoconus, which is a very rare presentation.

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How to Cite

Gohari, M., Shojaei, A., Rahmatkha, S., & Salehi, H. (2017). A Rare Case of Concurrent Granular Corneal Dystrophy and Keratoconus. Journal of Ophthalmic and Optometric Sciences, 1(1), 37–41. https://doi.org/10.22037/joos.v1i1.16496
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References

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Cremona FA, Ghosheh FR, Rapuano CJ, Eagle RC Jr, Hammersmith KM, Laibson PR, et al. Keratoconus associated with other corneal dystrophies. Cornea. 2009;28(2):127-35.

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Dighiero P, Valleix S, D'Hermies F, Drunat S, Ellies P, Savoldelli M, et al. Clinical, histologic, and ultrastructural features of the corneal dystrophy caused by the R124L mutation of the BIGH3 gene. Ophthalmology. 2000;107(7):1353-7.

Mashima Y, Nakamura Y, Noda K, Konishi M, Yamada M, Kudoh J, et al. A novel mutation at codon 124 (R124L) in the BIGH3 gene is associated with a superficial variant of granular corneal dystrophy. Arch Ophthalmol. 1999;117(1):90-3.

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Lyons CJ, McCartney AC, Kirkness CM, Ficker LA, Steele AD, Rice NS. Granular corneal dystrophy. Visual results and pattern of recurrence after lamellar or penetrating keratoplasty. Ophthalmology. 1994;101(11):1812-7.

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