Investigate the effect of alcohol on the human body from the perspective of verses of the Holy Quran, Hadith and Traditional medicine

  • Zeinab Malakzadeh School of Arts religions and civilizations, Isfahan University of Art, Isfahan, Iran.
  • Nayeb Ali Ahmadi Department of Medical Lab technology, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Vahideh Nasr School of Medicine, Shahid Beheshti University of Medical Sciences and Health Services, Tehran, Iran.


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Background and Objectives: Humans for thousands of years have used the alcoholic drinks. Jabir ibn Hayyan, has done purification of ethanol, for the first time. Studies show that 20% of men and 10% of women in many Western societies are involved with alcohol-related diseases. Ethanol consumption leads to various physical and mental damages in nervous system, cardiovascular system, reproductive system, digestive system, endocrine system, respiratory system, immune system and blood, embryos and many. Quran in Verse 219 of Baqare, verse 90 and 91 of Al Maydh, verse 43 of Nisa and traditions of the Imams warn the Muslims from drinking the wines, frankly. Traditional medicine has similar approach to alcohol consumption. Review of the updated medical studies on compliance with this order based on Islamic-Iranian culture in terms of physical and mental health are the objectives of this study.

Materials & Methods: The study is descriptive-library research that alcohol consumption and its impact on physical and mental health have been investigated from the perspective of verses, hadith and traditional medicine and also its compliance with the results of medical studies have been considered. In this study, all relevant ethical issues were considered.

Results: The study shows that alcohol has negative effects on the human body and spirit, and the results of medical studies are along with the instructions of Islam.

Conclusion: They have been proved that Islam not only belongs to its time, but also it has comprehensive program of spiritual and worldly happiness for all time.


Alcohol,Health, Medical research, Quran, Traditional medicine

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Please cite this article as: Malakzadeh Z, Ahmadi N­, Nasr V. Investigate the effect of alcohol on the human body from the perspective of verses of the Holy Quran, Hadith and Traditional medicine. J Res Relig Health.2017;3(1): 102- 120.


Majlisi MB. Bihar al-anwar. Beirut: Al-Wafa; 1983.

Amoli SJM. Al-Sahih Men Sirat Al-Nabi Al-Azam. Qom: darolhadith; 1377.

Tabatabayi M. Almizan. Qom: Jame-e Modarresin-e Huzeh Elmiyeh Pub; 2009.

Sobhani J. Forughe Abadiat. Qom: bustaneketab; 2010.

The holy Quran.Al-baghareh.verse 219. Translated by: Ayatollah Al-ozma Naser Makarem Shirazi. Qom: Imam Ali Ebne Abi Taleb (Ýa); 2010. (Full Text in Arabic)

Makarem Shirazi N. Tafsir Nemooneh: Darolkotob; 1992.

Taleghani M. A shining ray from Quran. Tehran: entesharco; 1983.

The holy Quran. Al-Maeda.Verse 90-91. Translated by: Ayatollah Al-ozma Naser Makarem Shirazi. Qom: Imam Ali Ebne Abi Taleb (Ýa); 2010. (Full Text in Arabic)

The holy Quran. An-Nesa.Verse 43. Translated by: Ayatollah Al-ozma Naser Makarem Shirazi. Qom: Imam Ali Ebne Abi Taleb (Ýa); 2010. (Full Text in Arabic)

The holy Quran.Al-baghareh.verse 173. Translated by: Ayatollah Al-ozma Naser Makarem Shirazi. Qom: Imam Ali Ebne Abi Taleb (Ýa); 2010. (Full Text in Arabic)

The holy Quran. Al-Maeda.Verse 3. Translated by: Ayatollah Al-ozma Naser Makarem Shirazi. Qom: Imam Ali Ebne Abi Taleb (Ýa); 2010. (Full Text in Arabic)

Khomeini R. Tahrir al-Wasilah. Qom: darol-elm 1988. Question 34 & 5.

Tabarsi H. Majma’al-Bayan. Tehran: Farahani; 1380.

Al-Hindi a-M. Kanz al-’ummal: Retrieved in May; 2000. Hadith 13756.

The holy Quran. Al-Nahl.Verse 67. Translated by: Ayatollah Al-ozma Naser Makarem Shirazi. Qom: Imam Ali Ebne Abi Taleb (Ýa); 2010. (Full Text in Arabic)

Shimamura AP, Jernigan TL, Squire LR. Korsakoff's syndrome: radiological (CT) findings and neuropsychological correlates. The Journal of neuroscience. 1988; 8(11): 4400-10.

American Psychiatric A, Task Force on D-I. Diagnostic and statistical manual of mental disorders : DSM-IV-TR. Washington, DC: American Psychiatric Association; 2000.

Schuckit MA. Alcohol-use disorders. The Lancet. 2009; 373(9662):492-501.

Farid M. Alhadis. 2 th ed. Tehran: daftarnashr Islamic Culture; 2007.

Cooper P. Poisoning by Drugs and Chemicals. Translated by farokhseyr and khuyi. Tehran: Ketabhaye Jibi Pub. p. 162.

Katzung B. Basic and Clinical Pharmacology. Translated by Malek Atayi. 9th ed. Tehran: Nasle Farda; 2004.

Al-Hindi a-M. Kanz al-’ummal . Lebanon: Dār al-Kutub al-‘Ilmīyah; 2000. Hadith 13180.

Bode C, Bode JC. Effect of alcohol consumption on the gut. Best Practice & Research Clinical Gastroenterology. 2003; 17(4): 575- 92.

Al-Hindi a-M. Kanz al-ummal. Lebanon: Dār al-Kutub al-‘Ilmīyah; 2000. Hadith 43958.

Ghosian-moghadam M, editor Alcoholic wines drinking Prohibition in Quran, and its effects on individual and society health. First National Quran and Medicine congress; Tehran. Iran. Shahed University; 2006. p. 82-100.

Haynes JC, Farrell M, Singleton N, Meltzer H, Araya R, Lewis G, et al. Alcohol consumption as a risk

factor for non-recovery from common mental disorder: results from the longitudinal follow-up of the National Psychiatric Morbidity Survey. Psychological medicine. 2008; 38(03): 451-5.

Saxton J, Munro CA, Butters MA, Schramke C, McNeil MA. Alcohol, dementia, and Alzheimer's disease: comparison of neuropsychological profiles. Journal of geriatric psychiatry and neurology. 2000; 13(3): 141-9.

DelBello MP, Strakowski SM, Sax KW, McElroy SL, Keck Jr PE, West SA, et al. Familial rates of affective and substance use disorders in patients with first-episode mania. Journal of affective disorders. 1999;56(1):55-60.

Nazem Al-jahan MAK. Nayer Azam (in recognition of the pulse and its variants). 2th ed. Tehran: Iranian Traditional Medicine; 2013. (Full Text in Persian)

Noorani M. Great Islamic Encyclopedia of Medicine. Tehran: Miraase Maktoob Publication Center; 2011. (Full Text in Persian)

Chaghmyny M. Text and Translation Qanvncheh fi Tibb. Tehran: Almae; 2012.

Courville CB. Effects of alcohol on the nervous system of man. 1955.

Dastgheib AH. Deadly sins. Qom: jameehmodarresin ḥawza ʻilmiyya; 2008.

Ameli H, ibn Hosein M. Wasā'il al-Shīʿa. Qum: tebyan; 2008.

Imam Reza. Reza medicine ( medical treatise of Imam Reza). Translated by Amir Sadeghi. Tehran: Javaheri; 2002. (Full Text in Persian)

Claus D, Eggers R, Engelhardt A, Neundörfer B, Warecka K. Ethanol and polyneuropathy. Acta Neurologica Scandinavica. 1985;72(3):312-6.

Klatsky AL. Alcohol and stroke: an epidemiological labyrinth. Stroke; a journal of cerebral circulation. 2005;36(9):1835-6.

Klatsky AL, Armstrong MA, Friedman GD, Sidney S. Alcohol drinking and risk of hemorrhagic stroke. Neuroepidemiology. 2002;21(3):115-22.

Stampfer MJ, Colditz GA, Willett WC, Speizer FE, Hennekens CH. A prospective study of moderate alcohol consumption and the risk of coronary disease and stroke in women. The New England journal of medicine. 1988;319(5):267-73.

Salami M, Anvari M. Deleterious effect of ethanol on spatial learning and memory. KAUMS Journal (FEYZ). 2006;10(3):9-15.

Gheorghiev C, De Montleau F, Defuentes G. [Alcohol and epilepsy: a case report between alcohol withdrawal seizures and neuroborreliosis]. L'Encephale. 2011;37(3):231-7.

Fernandez-Sola J, Nicolas JM, Oriola J, Sacanella E,

Estruch R, Rubin E, et al. Angiotensin-converting enzyme gene polymorphism is associated with vulnerability to alcoholic cardiomyopathy. Annals of internal medicine. 2002;137(5 Part 1):321-6.

Nicolas JM, Fernandez-Sola J, Estruch R, Pare JC, Sacanella E, Urbano-Marquez A, et al. The effect of controlled drinking in alcoholic cardiomyopathy. Annals of internal medicine. 2002;136(3):192-200..

Frost L, Vestergaard P. Alcohol and risk of atrial fibrillation or flutter: a cohort study. Archives of internal medicine. 2004;164(18):1993-8.

Mukamal KJ, Tolstrup JS, Friberg J, Jensen G, Gronbaek M. Alcohol consumption and risk of atrial fibrillation in men and women: the Copenhagen City Heart Study. Circulation. 2005;112(12):1736-42.

Sasaki S. Alcohol and its relation to all-cause and cardiovascular mortality. Acta cardiologica. 2000; 55(3): 151-6.

Zilkens RR, Burke V, Hodgson JM, Barden A, Beilin LJ, Puddey IB. Red wine and beer elevate blood pressure in normotensive men. Hypertension. 2005; 45(5): 874-9.

Klatsky AL. Alcohol and hypertension. Clinica Chimica Acta. 1996;246(1):91-105.

Bha’aldvlh B. kholasat Al-tajareb. Tehran: University of Medical Sciences. Research Institute for Islamic & Complementary Medicine; 2003.

Jafarpur M, Mofidpur H, Ebrahimzadeh A. The effects of ethanol on the microscopic structure of testis in mice. 2005.

Jafarpur M, Ebrahimzadeh A. Study of ovarian Histological changes after Ethanol consumption. The Horizon of Medical Sciences. 2006;11(4):19-23.

Ghosian-moghadam M, Ahmadi M, editors. Sexual Disorders due to alcoholic wines consumption. 4th congress on family and sexual health; Tehran. Iran. Shahed University;2009.

Ghosian-moghadam M, Ayres Z, editors. Libido and therapeutic ways to increase and decrease it, in traditional medicine. 4th congress on family and sexual health; Tehran. Iran. Shahed University;2009.

Cholet F, Nousbaum J-B, Richecœur M, Oger E, Cauvin J-M, Lagarde N, et al. Factors associated with liver steatosis and fibrosis in chronic hepatitis C patients. Gastroenterologie clinique et biologique. 2004; 28(3): 272-8.

Day CP. Who gets alcoholic liver disease: nature or nurture? Journal of the Royal College of Physicians of London. 1999;34(6):557-62.

Lelbach WK. Cirrhosis in the alcoholic and its relation to the volume of alcohol abuse. Annals of the New York Academy of Sciences. 1975;252(1):85-105.

Safdar K, Schiff ER. Alcohol and hepatitis C. Seminars in liver disease; New York: Thieme Medical

Publishers; 2004. p. 305-15.

Schiff ER, Ozden N. Hepatitis C and alcohol. Alcohol Research & Health. 2003;27(3):232-40.

Maddrey WC, Boitnott JK, Bedine MS, Weber FL, Mezey E, White RI. Corticosteroid therapy of alcoholic hepatitis. Gastroenterology. 1978;75(2):193-9.

Apte M, Pirola R, Wilson J. New insights into alcoholic pancreatitis and pancreatic cancer. Journal of gastroenterology and hepatology. 2009; 24 Suppl 3: S51-6.

Apte MV, Wilson JS. Alcohol-induced pancreatic injury. Best practice & research Clinical gastroenterology. 2003; 17(4): 593-612.

Braganza JM, Lee SH, McCloy RF, McMahon MJ. Chronic pancreatitis. The Lancet. 2011;377(9772):1184-97.

Vonlaufen A, Wilson JS, Pirola RC, Apte MV. Role of alcohol metabolism in chronic pancreatitis. Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism. 2007;30(1):48-54.

Apte MV, Pirola RC, Wilson JS. Mechanisms of alcoholic pancreatitis. Journal of gastroenterology and hepatology. 2010;25(12):1816-26.

Khosravi Hamadani AA. Guide health drugs. Tehran: Iran University of Medical Sciences. Research Institute for Islamic & Complementary Medicine; 2007.

Esmeltezer S, Brunner L. Text book of medical surgical nursing. Philadelphia, WB: Saunders. 2008.

Bikle DD, Genant HK, Cann C, Recker RR, Halloran BP, Strewler GJ. Bone disease in alcohol abuse. Annals of internal medicine. 1985;103(1):42-8.

Cook RT. Alcohol abuse, alcoholism, and damage to the immune system-a review. Alcoholism: Clinical and Experimental Research. 1998;22(9):1927-42.

Ballard HS. Hematological complications of alcoholism. Alcoholism: Clinical and Experimental Research. 1989; 13(5): 706-20.

Ioannou GN, Dominitz JA, Weiss NS, Heagerty PJ, Kowdley KV. The effect of alcohol consumption on the prevalence of iron overload, iron deficiency, and iron deficiency anemia. Gastroenterology. 2004; 126(5): 1293- 301.

Mofidpoor H, Jafarpoor M, Ebrahimzadeh A. The study of ethanol effects on microscopic structure of the lung in adult mouse. The Horizon of Medical Sciences. 2007; 13(3): 20-4.

Kornum JB, Due KM, Norgaard M, Tjonneland A, Overvad K, Sorensen HT, et al. Alcohol drinking and risk of subsequent hospitalisation with pneumonia. The European respiratory journal. 2012;39(1):149-55.

House GBP. Report from the Select Committee on Inquiry Into Drunkenness, with Minutes of Evidence, and Appendix. Ordered, by the House of Commons, to be Printed, 5 August 1834.[London, 1834]: Irish University Press; 1968.

Lemoine P, Harousseau H, Borteyru J, Menuet J. Les enfants de parents alcooliques: Anomalies observees a propos de 127 cas. Ouest méd. 1968;21(476-482):2.

Abel EL, Sokol RJ. Incidence of fetal alcohol syndrome and economic impact of FAS-related anomalies. Drug and alcohol dependence. 1987; 19(1): 51-70.

Beattie J. Fetal alcohol syndrome-the incurable hangover. Health visitor. 1981;54(11):468-9.

Forbes R. Alcohol-related birth defects. Public health. 1984; 98(4):238-41.

Holland M. Alcohol and the unborn child: the fetal alcohol syndrome. International Journal of Environmental Studies. 1981; 17(1): 67-71.

Sandor GG, Smith DF, MacLeod PM. Cardiac malformations in the fetal alcohol syndrome. The Journal of pediatrics. 1981; 98(5): 771-3.

Schenker S, Becker HC, Randall CL, Phillips DK, Baskin GS, Henderson GI. Fetal alcohol syndrome: current status of pathogenesis. Alcoholism: Clinical and Experimental Research. 1990;14(5):635-47.

Streissguth A. The behavioral teratology of alcohol: Performance, behavioral, and intellectual deficits in prenatally exposed children. Alcohol and brain development. New York: Oxford University Press 1986. p. 3-44.

Streissguth A. Fetal alcohol syndrome: early and long-term consequences. Nida Res Monogr. 1992; 119: 126-30.

Streissguth A, Clarren S, Jones K. Natural history of the fetal alcohol syndrome: A 10-year follow-up of eleven patients. The Lancet. 1985;326(8446):85-91.

Astley SJ. Profile of the first 1,400 patients receiving diagnostic evaluations for fetal alcohol spectrum disorder at the Washington State Fetal Alcohol Syndrome Diagnostic & Prevention Network. Can J Clin Pharmacol. 2010;17(1): 132-64.

Elgen I, Bruaroy S, Laegreid LM. Lack of recognition and complexity of foetal alcohol neuroimpairments. Acta paediatrica. 2007; 96(2): 237-41.

Lewis DD. Alcohol & pregnancy outcome. Midwives chronicle. 1983; 96(1151): 420-2.

Dursun I, Jakubowska-Dogru E, van der List D, Liets LC, Coombs JL, Berman RF. Effects of early postnatal exposure to ethanol on retinal ganglion cell morphology and numbers of neurons in the dorsolateral geniculate in mice. Alcoholism, clinical and experimental research. 2011;35(11):2063-74.

Hanson JW, Jones KL, Smith DW. Fetal alcohol syndrome: Experience with 41 patients. Jama. 1976; 235(14): 1458-60.

Streissguth AP. Psychologic handicaps in children with the fetal alcohol syndrome. Annals of the New York Academy of Sciences. 1976;273(1):140-5.

Streissguth AP, Herman CS, Smith DW. Intelligence, behavior, and dysmorphogenesis in the fetal alcohol syndrome: A report on 20 patients. The Journal of pediatrics. 1978;92(3):363-7.

Streissguth AP, Herman CS, Smith DW. Stability of intelligence in the fetal alcohol syndrome: A preliminary report. Alcoholism: Clinical and Experimental Research. 1978;2(2):165-70.

Clarren SK, Smith DW. The fetal alcohol syndrome. New England Journal of Medicine. 1978;298(19):1063-7.

Spohr H-L, Steinhausen H-C. Follow-up studies of children with fetal alcohol syndrome. Neuropediatrics. 1987;18(01):13-7.

Streissguth AP, Barr HM, Sampson PD, Bookstein FL, Darby BL. Neurobehavioral effects of prenatal alcohol: Part I. Research strategy. Neurotoxicology and teratology. 1989;11(5):461-76.

Razi s. Nahj al-Balagha Imam Ali. Qom: Mashrqyn; 2000.

Smith D. Fetal drug syndromes: Effects of ethanol and hydantoins. Pediatrics in Review. 1979;1(5):165-72.

Smith DW, Knights J. Mothering your unborn baby: WB Saunders Co; 1979.

Tittmar H-G. Some effects of alcohol on reproduction. Alcohol and Alcoholism. 1978; 13(3): 122-38.

Vorhees CV, Mollnow E. Behavioral teratogenesis: Long-term influences on behavior from early exposure to environmental agents. 1987.

West JR, Pierce DR. Perinatal alcohol exposure and neuronal damage. Alcohol and brain development: Oxford University Press, New York; 1986. p. 120-57.

Woollam D. Alcohol and the Safety of the Unborn Child. The Journal of the Royal Society for the Promotion of Health. 1981;101(6):241-4.

Aminigram P RTM, Zamanian Azodi M, Bagheri B, Nasr R, Akbari Eidgahi M R. Ethanol- induced chromosomal abnormalities in human fibroblast cells. koomesh. 2015;16(2):254-9.

Amini S. Teratogenic effects of ethanol in quackenbush special mouse. 2000.

Streissguth A, Barr H, Kogan J, Bookstein F. Understanding the occurrence of secondary disabilities in clients with fetal alcohol syndrome (FAS) and fetal alcohol effects (FAE). Final report to the Centers for Disease Control and Prevention (CDC)1996. p. 96-06.

Siegmund SV, Singer MV. Effects of alcohol on the upper gastrointestinal tract and the pancreas-an up-to-date overview. Zeitschrift fur Gastroenterologie. 2005;43(8):723-36.

Parazzini F, La Vecchia C, D'Avanzo B, Moroni S, Chatenoud L, Ricci E. Alcohol and endometrial cancer risk: findings from an Italian case-control study. Nutrition and cancer. 1995;23(1):55-62.

Swanson CA, Wilbanks GD, Twiggs LB, Mortel R, Berman ML, Barrett RJ, et al. Moderate alcohol consumption and the risk of endometrial cancer. Epidemiology. 1993;4(6):530-6.

Choi JY, Abel J, Neuhaus T, Ko Y, Harth V, Hamajima N, et al. Role of alcohol and genetic polymorphisms of CYP2E1 and ALDH2 in breast cancer development. Pharmacogenetics. 2003;13(2):67-72.

Kawamoto T, Koga M, Murata K, Matsuda S, Kodama Y. Effects of ALDH2, CYP1A1, and CYP2E1 genetic polymorphisms and smoking and drinking habits on toluene metabolism in humans. Toxicology and applied pharmacology. 1995;133(2):295-304.

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