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  3. Vol. 4 No. 1 (2022): March
  4. Short Communication

March
Vol. 4 No. 1 (2022)

Opium-Induced Bowel Dysfunction: A hospital survey in two academic centers of Iran

  • Dorsa Daneshbakhsh
  • Shayan Sheikhmiri
  • Mostafa Hamdieh
  • Mitra Rahimi

School of Medicine Students' Journal, Vol. 4 No. 1 (2022),
https://doi.org/10.22037/smsj.v4i1.38831 Published 7 January 2023

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Abstract

Background and aim: Opioids abuse is associated with several gastrointestinal side effects. We evaluated the prevalence of gastrointestinal symptoms in OIBD in hospitalized patients in different wards of Shahid Beheshti University of Medical Sciences (SBMU) hospitals. This study aimed to investigate patients' frequency symptoms treated with opioids and opium addicts and their derivatives.


Materials and Methods: The present study is a descriptive study conducted from April 2018 to October 2018. Direct interviews with the study population were performed for data collection. Their information, symptoms, and complaints were checked.


Results: Among the gastrointestinal symptoms, constipation was the most common symptom (59.3%). This pattern is followed by bloating (28.6%), heartburn (27.1%), abdominal pain (25.7%), dysphagia (22.9%), gastroesophageal reflux disease (22.1%), nausea (12.1%), and vomiting (7.9 %) and diarrhea (5 %) were the next prevalent symptoms, respectively.


Conclusion: Finally, our study showed that OBID symptoms are present in most opioid users and most of these people suffer from constipation. Also, the type of substance consumed by the person, the duration of continuous use and cigarette smoking play a role in the incidence of these symptoms.

Keywords:
  • Gastrointestinal symptoms, Constipation, Opioids, Addiction, OIBD

How to Cite

1.
Daneshbakhsh D, Sheikhmiri S, Hamdieh M, Rahimi M. Opium-Induced Bowel Dysfunction: A hospital survey in two academic centers of Iran. Sch Med Stud J [Internet]. 2023Jan.7 [cited 2023Feb.8];4(1). Available from: https://journals.sbmu.ac.ir/smsj/article/view/38831
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References

1. Drewes, A.M., et al., Definition, diagnosis and treatment strategies for opioid-induced bowel dysfunction–recommendations of the Nordic Working Group. Scandinavian journal of pain, 2016. 11(1): p. 111-122.
2. Camilleri, M., et al., Emerging treatments in neurogastroenterology: a multidisciplinary working group consensus statement on opioid‐induced constipation. Neurogastroenterology & Motility, 2014. 26(10): p. 1386-1395.
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8. Cook, S., et al., Gastrointestinal side effects in chronic opioid users: results from a population‐based survey. Alimentary pharmacology & therapeutics, 2008. 27(12): p. 1224-1232.
9. Kulich, K.R., et al., Reliability and validity of the Gastrointestinal Symptom Rating Scale (GSRS) and Quality of Life in Reflux and Dyspepsia (QOLRAD) questionnaire in dyspepsia: a six-country study. Health and quality of life outcomes, 2008. 6(1): p. 1-12.
10. Locke III, G.R., et al., Psychosocial factors are linked to functional gastrointestinal disorders: a population based nested case-control study. Official journal of the American College of Gastroenterology| ACG, 2004. 99(2): p. 350-357.
11. Mahajan, R., et al., Clinical profile and outcomes of opioid abuse gastroenteropathy: an underdiagnosed disease entity. Intestinal research, 2020. 18(2): p. 238.
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