ISSN: 2676-7597
Vol. 2 No. 3 (2020)
Investigating the relationship between gastric polyp and dyspepsia in Iranian patients
School of Medicine Students' Journal,
Vol. 2 No. 3 (2020),
1 July 2020
,
Page 7-13
https://doi.org/10.22037/smsj.v2i3.30888
Abstract
Abstract
Background and aim: Chronic dyspepsia is one of the common medical problems in patients referred to internal and gastrointestinal clinics. According to the results of some studies, most patients with dyspepsia are simultaneously suffering from gastric polyps. We aimed to clarify the association of gastric polyp and dyspepsia in an Iranian population.
Materials and methods: We enrolled 2772 dyspeptic and 1294 non-dyspeptic subjects in this cross-sectional study, who referred to the gastrointestinal clinic at Ayatollah Taleghani Hospital in Tehran from2016 to 2018.All subjects underwent upper gastrointestinal (GI) endoscopy andpatients with GI malignancy, severe GI bleeding and history of GI surgery excluded from study. They were evaluated for age, sex, endoscopicfindings, gastric polyp (GP) count, size and localization, diagnosticmethods used for histology, and polyp features. The relationshipbetween gastric polyp and dyspepsia was alsoevaluated.
Results: In 4066 consecutive upper GI endoscopy in patients with and without dyspepsia, 129 patients (3.2%) had gastric polyps (GPs).The prevalence of GPs was 3.04% and 3.32% in with and without dyspepsia subjects, respectively. There was no observed statistically significant relationship between GPs and dyspepsia (P=0.709). Hyperplastic polyps(HPs)were the most common pathologic form in patients with and without dyspepsia in 53.5% and 34.9% of patients, respectively. The most common location was the gastric antrum polyps (76.7%) and the common size of the polyps was between 5-10 mm in (80.6%) patients.
Conclusion: In the present study, there was no statistically significant difference within the pathologic findings of gastric polyp in terms of dyspepsia.Hyperplastic polyps(HPs) are the most common type of pathologic stomach polyps and it is maybe high due to the highfrequency of Helicobacter pylori(H. pylori) infection in our country.
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References
References
Stanghellini V, Chan FK, Hasler WL, Malagelada JR, Suzuki H, Tack J, et al. Gastroduodenal Disorders. Gastroenterology. 2016;150(6):1380-92.
Mahadeva S, Goh KL. Epidemiology of functional dyspepsia: a global perspective. World journal of gastroenterology. 2006;12(17):2661-6.
Amini E, Keshteli AH, Jazi MS, Jahangiri P, Adibi P. Dyspepsia in Iran: SEPAHAN Systematic Review No. 3. International journal of preventive medicine. 2012;3(Suppl 1):S18-25.
Ford AC, Marwaha A, Sood R, Moayyedi P. Global prevalence of, and risk factors for, uninvestigated dyspepsia: a meta-analysis. Gut. 2015;64(7):1049-57.
Futagami S, Shimpuku M, Yin Y, Shindo T, Kodaka Y, Nagoya H, et al. Pathophysiology of functional dyspepsia. Journal of Nippon Medical School = Nippon Ika Daigaku zasshi. 2011;78(5):280-5.
Yarandi SS, Christie J. Functional Dyspepsia in Review: Pathophysiology and Challenges in the Diagnosis and Management due to Coexisting Gastroesophageal Reflux Disease and Irritable Bowel Syndrome. Gastroenterology research and practice. 2013;2013:351086.
Olmez S, Sayar S, Saritas B, Savas AY, Avcioglu U, Tenlik I, et al. Evaluation of patients with gastric polyps. Northern clinics of Istanbul. 2018;5(1):41-6.
Velazquez-Dohorn ME, Lopez-Durand CF, Gamboa-Dominguez A. Changing Trends in Gastric Polyps. Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion. 2018;70(1):40-5.
Goddard AF, Badreldin R, Pritchard DM, Walker MM, Warren B. The management of gastric polyps. Gut. 2010;59(9):1270-6.
Ugiagbe R, Omuemu C. Diagnostic indications for upper gastrointestinal endoscopy. Annals of Biomedical Sciences. 2012;11(2):65-70.
Vaira D, Holton J, Osborn J, D'Anna L, Romanos A, Falzon M, et al. Endoscopy in dyspeptic patients: is gastric mucosal biopsy useful? The American journal of gastroenterology. 1990;85(6):701-4.
Kyzekove J, Arlt J, Arltova M. Is there any relationship between functional dyspepsia and chronic gastritis associated with Helicobacter pylori infection? Hepato-gastroenterology. 2001;48(38):594-602.
Wang FW, Young SC, Chen RY, Lin KH, Chen YH, Hsu PI, et al. The Prevalence and Risk Factors of Gastric Polyp in Asymptomatic Patients Receiving Health Examination. Gastroenterology research and practice. 2018;2018:9451905.
Tahara T, Arisawa T, Shibata T, Nakamura M, Okubo M, Yoshioka D, et al. Association of endoscopic appearances with dyspeptic symptoms. Journal of gastroenterology. 2008;43(3):208-15.
Sorouri M, Pourhoseingholi MA, Vahedi M, Safaee A, Moghimi-Dehkordi B, Pourhoseingholi A, et al. Functional bowel disorders in Iranian population using Rome III criteria. Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association. 2010;16(3):154-60.
Ari A, Buyukasik K, Segmen O. Polyps of the upper gastrointestinal tract: 10-year clinical experience and review of the literature. Int J Clin Exp Med. 2016;9(4):7339-42.
Vatansever S, Akpinar Z, Alper E, Ipek S, Yazicioglu N, Ekinci N, et al. Gastric polyps and polypoid lesions: Retrospective analysis of 36650 endoscopic procedures in 29940 patients. The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology. 2015;26(2):117-22.
Morais DJ, Yamanaka A, Zeitune JM, Andreollo NA. Gastric polyps: a retrospective analysis of 26,000 digestive endoscopies. Arquivos de gastroenterologia. 2007;44(1):14-7.
Garcia-Alonso FJ, Martin-Mateos RM, Gonzalez Martin JA, Foruny JR, Vazquez-Sequeiros E, Boixeda de Miquel D. Gastric polyps: analysis of endoscopic and histological features in our center. Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva. 2011;103(8):416-20.
Carmack SW, Genta RM, Schuler CM, Saboorian MH. The current spectrum of gastric polyps: a 1-year national study of over 120,000 patients. The American journal of gastroenterology. 2009;104(6):1524-32.
Archimandritis A, Spiliadis C, Tzivras M, Vamvakousis B, Davaris P, Manika Z, et al. Gastric epithelial polyps: a retrospective endoscopic study of 12974 symptomatic patients. The Italian journal of gastroenterology. 1996;28(7):387-90.
Elhanafi S, Saadi M, Lou W, Mallawaarachchi I, Dwivedi A, Zuckerman M, et al. Gastric polyps: Association with Helicobacter pylori status and the pathology of the surrounding mucosa, a cross sectional study. World journal of gastrointestinal endoscopy. 2015;7(10):995-1002.
Gencosmanoglu R, Sen-Oran E, Kurtkaya-Yapicier O, Avsar E, Sav A, Tozun N. Gastric polypoid lesions: analysis of 150 endoscopic polypectomy specimens from 91 patients. World journal of gastroenterology. 2003;9(10):2236-9.
Ashtari S, Pourhoseingholi MA, Molaei M, Taslimi H, Zali MR. The prevalence of Helicobacter pylori is decreasing in Iranian patients. Gastroenterol Hepatol Bed Bench. 2015;8(Suppl 1):S23-9.
Fakheri H, Saberi Firoozi M, Bari Z. Eradication of Helicobacter Pylori in Iran: A Review. Middle East journal of digestive diseases. 2018;10(1):5-17.
Jalving M, Koornstra JJ, Wesseling J, Boezen HM, S DEJ, Kleibeuker JH. Increased risk of fundic gland polyps during long-term proton pump inhibitor therapy. Alimentary pharmacology & therapeutics. 2006;24(9):1341-8.
Fan NN, Yang J, Sun G, Lu ZS, Ling Hu EQ, Wang XD, et al. Changes in the spectrum of gastric polyps in the Chinese population. World journal of gastroenterology. 2015;21(33):9758-64.
Bilibou M, Barboi O, Darie A, Khan A, Drug V. Gastric polyps precancerous conditions. Endoscopy. 2018;50(40):eP036.
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