COVID-19 associated Kawasaki-like multisystem inflammatory syndrome in an adult female with oral, ophthalmic and cardiac manifestation, a case report
Iranian Journal of Emergency Medicine,
Vol. 10 No. 1 (2023),
30 November 2022
,
Page e16
https://doi.org/10.22037/ijem.v10i1.41658
Abstract
Kawasaki disease is an acute febrile disease with the vasculitis of small and medium vessels that mainly affects children under the age of five, usually occurring after a viral respiratory disease. During the coronavirus disease-19 (COVID-19) pandemic, a significant increase was reported in the number of children with symptoms similar to Kawasaki disease, which is known as a multi-system inflammatory syndrome in children (MIS-C). A Kawasaki-like disease is rare in adults, especially in the context of COVID-19. We hereby present the case of A 41 year old female patient presented with complaints of bleeding from the gums and red and watery eyes, high fever, sore throat, weakness, and lethargy. She mentioned a recent contact with a COVID-19 patient. Covid-19 was confirmed by a positive reverse transcription polymerase chain reaction (RT-PCR) test. Other lab tests and clinical manifestations revealed inflammatory phenomena that fully complied with multi-system inflammatory syndrome in adults (MIS-A) criteria. The patient was treated with a possible diagnosis of MIS-A in the context of COVID-19 and was discharged in good general condition. COVID-19 rarely presents in adults without clear respiratory symptoms and in the form of multisystem inflammatory syndrome (MIS-A). Due to the possibility of irreversible complications, MIS-A requires special attention and early diagnosis and treatment.
- multisystem inflammatory syndrome
- MIS-A, adult
- COVID-19
- Kawasaki disease
How to Cite
References
Elouardi Y, Rebahi H, Zarrouki Y, Ziadi A, Younous S, Samkaoui M. COVID-19 associated Kawasaki-like multisystem inflammatory syndrome in an adult. Revista Española de Anestesiología y Reanimación (English Edition). 2022;69(1):43-7.
Pouletty M, Borocco C, Ouldali N, Caseris M, Basmaci R, Lachaume N, et al. Paediatric multisystem inflammatory syndrome temporally associated with SARS-CoV-2 mimicking Kawasaki disease (Kawa-COVID-19): a multicentre cohort. Annals of the rheumatic diseases. 2020;79(8):999-1006.
Alizargar J. The novel coronavirus (COVID-19) and the risk of Kawasaki disease in children. Journal of the Formosan Medical Association. 2020;119(11):1713.
Shaigany S, Gnirke M, Guttmann A, Chong H, Meehan S, Raabe V, et al. An adult with Kawasaki-like multisystem inflammatory syndrome associated with COVID-19. The Lancet. 2020;396(10246):e8-e10.
Prevention CfDCa. Multisystem Inflammatory Syndrome in Adults (MIS-A) Case Definition and Information for Healthcare Providers [Available from: https://www.cdc.gov/mis/mis-a/hcp.html.
Behzadi F, Ulloa NA, Danckers M. Multisystem inflammatory syndrome in adults: A case report and review of the literature. Journal of Medical Case Reports. 2022;16(1):1-20.
Patel P, DeCuir J, Abrams J, Campbell AP, Godfred-Cato S, Belay ED. Clinical characteristics of multisystem inflammatory syndrome in adults: a systematic review. JAMA network open. 2021;4(9):e2126456-e.
Worku D. Multisystem Inflammatory Syndrome in Adults (MIS-A) and SARS-CoV2: An Evolving Relationship. BioMed. 2023;3(1):195-201.
Hennon TR, Penque MD, Abdul-Aziz R, Alibrahim OS, McGreevy MB, Prout AJ, et al. COVID-19 associated multisystem inflammatory syndrome in children (MIS-C) guidelines; a Western New York approach. Elsevier; 2020. p. 101232.
McArdle AJ, Cunnington AJ, Levin M. Therapy for Multisystem Inflammatory Syndrome in Children. Reply. The New England journal of medicine. 2021.
Sokolovsky S, Soni P, Hoffman T, Kahn P, Scheers-Masters J. COVID-19 associated Kawasaki-like multisystem inflammatory disease in an adult. The American journal of emergency medicine. 2021;39:253. e1-. e2.
Hookham L, Fisher C, Manson JJ, Morgan M, O'Hara G, Riley P, et al. Understanding the diagnosis and management of multisystem inflammatory syndrome in adults (MIS-A) in the UK: results of a national Delphi process. Clinical Medicine. 2022;22(3):266.
- Abstract Viewed: 107 times
- pdf Downloaded: 100 times