Men's Health Journal <p><strong>Men's health journal (MHJ)</strong> is an international, peer-reviewed, totally free (Submission and Publication) and open access scientific journal. <span id="m_-4478816413475032476gmail-m_9057906418031166658yui_3_16_0_ym19_1_1530780613503_2845">The MHJ&nbsp;<span id="m_-4478816413475032476gmail-m_9057906418031166658yui_3_16_0_ym19_1_1530780613503_3745">m</span></span>ulti-professional aspects&nbsp;including: Urology, Andrology, Cardiology, Endocrinology, Oncology, Gastroentrology, Nutrition, Genetics, Neurology, Pulmonology, Trauma, Gerontology, Psychiatry, Psychology, Sexual Reproductive medicine and public health,&nbsp;Occupational health, Mental health and wellbeing, Environmental health, HIV/AIDS/STIs, nursing, Epidemiology and Biostatistics, Psychological &amp; Behavioral issues related to men, Health promotion, prevention and lifestyle, Marginalized male populations such as incarcerated men, homeless men, homosexual men, and minorities, Health System Research (HSR) and Health policies impacting men's health.</p> SBMU Journals en-US Men's Health Journal 2645-3614 <h3><span style="font-size: 10px;">Based on the obtained author agreement upon submission, "</span><span style="font-size: 10px;">Shahid Beheshti University of Medical Sciences</span><span style="font-size: 10px;">" is the copyright owner of the published material. However, according to Bethesda Statement, all works published in this journal are open access and freely available to anyone on the journal web site without cost under creative common license BY-NC.&nbsp;Based on this license, under the condition of proper citation, “Emergency” grants to all users the following rights:</span></h3> <p>1. Free, irrevocable, worldwide, perpetual access to all published materials.</p> <p>2. To copy, use, distribute, transmit and display the work on third party repositories and social media.</p> <p>3. To make and distribute derivative works in any digital medium for any non-commercial purpose.</p> Association Between Premature Ejaculation and Religious Orientation <p><strong>Introduction: </strong>Premature ejaculation (PE) is the most common male sexual dysfunction. Although its etiology is not fully understood, several organic and psychological disorders have been identified as risk factors. The main aim of this study is to find any association between religious orientation (RO) and PE. <strong>&nbsp;</strong></p> <p><strong>Methods: </strong>We designed a cross-sectional study and 80 participants with PE as the main chief complaint were enrolled. After filling informed consent, all participants have filled two questionnaires including the Premature Ejaculation Diagnostic Tool (PEDT) for PE and the Allport &amp; Ross intrinsic-Extrinsic Religious Orientation Scale for RO assessment respectively. Spearman's rho analysis was used for assessing the association between PEDT scores and ROS scores by SPSS 22.0 version.</p> <p><strong>Results:&nbsp; </strong>Out of 80 patients with mean age 35.56 ± 8.46 years, 70 patients (87.5%) had PEDT positive score. Of them, 45 (64%) had lifelong PE and 25 (36%) experienced an acquired PE. Correlation analysis was shown a reverse correlation between PEDT positive scores and Intrinsic RO (P = 0.05) with a correlation coefficient -0.311, PEDT positive and negative scores was not correlated with extrinsic RO (P= 1).</p> <p><strong>Conclusion: </strong>Patients with a lower intrinsic religious orientation score have a higher probability for PE and PEDT positive score.</p> Reza Sari Motlagh Nayyer Sari Motlagh Reihan Shenasi Amirreza Kafi Kang M.Reza Roshandel Copyright (c) 2021 Men's Health Journal 2021-01-10 2021-01-10 5 1 e2 e2 10.22037/mhj.v5i1.33063 Bleeding in Patients with Atrial Fibrillation Plus Coronary Artery Disease under Triple anti-Coagulant Therapy <p><strong>Introduction: </strong>Regarding scarce knowledge about bleeding in non-valvular atrial fibrillation (AF) patients with simultaneous coronary artery disease (CAD) under triple anti-coagulant therapy, this study was carried out to recognize the risk of hemorrhage and preventive programming.</p> <p><strong>Materials and Methods:</strong> In this performed prospective, 150 consecutive patients with non-valvular atrial fibrillation and concurrent coronary disease, candidate for triple therapy with Asprin 80 mg, Clopidogrel 75 mg and Rivaroxaban 15 mg (in Shohada, Loghman, Modarres, and Labafinezhad centers, in Tehran, Iran during Jan 2019 to Jan 2020 were enrolled and the incidence rate of bleeding and compliance were evaluated for one month.</p> <p><strong>Results:</strong> The results in this study demonstrated that 87.3% had compliance and completely use three drugs. Bleeding occurred in 0.6 % (4 patients), no major bleeding , only one minor bleeding as GIB, three minimal cases (totally 4 bleeding cases), 3 cases with epistaxis, 7 patients with ecchymosis, 6 subjects with hematuria, no one required discontinuation of drug. Diabetes mellitus, hypertension, female sex, older age, higher HASBLED Score, and higher CHADS-VASC Score were related to lack of compliance (P &lt; 0.05).</p> <p><strong>Conclusion:</strong> Incidence rate of bleeding in atrial fibrillation plus coronary concurrent patients, candidate for triple therapy with ASA, Clopidogrel and Rivaroxaban is low. Also the bleeding is minor and the compliance is high showing that majority of cases use routinely these triple therapy regimen.</p> Mehdi Pishgahi Marjan Rashidi Reza Arefizade Copyright (c) 2021 Men's Health Journal 2021-01-13 2021-01-13 5 1 e3 e3 10.22037/mhj.v5i1.33712 Comparing the Effect of Vitamin E and N-Acetylcysteine on Prevention of Contrast-Induced Nephropathy in Diabetic Patients under Coronary Angiography <p><strong>Introduction:&nbsp; </strong>Considering the incidence of contrast&nbsp; induced&nbsp; nephropathy&nbsp; (CIN) as well as&nbsp; its&nbsp; complications&nbsp; and&nbsp;&nbsp;&nbsp; costs,&nbsp; prevention&nbsp; and&nbsp; reducing&nbsp; the&nbsp; risk&nbsp; of&nbsp; CIN&nbsp; is&nbsp; an&nbsp; essential&nbsp; issue.&nbsp; The&nbsp; present&nbsp; study&nbsp; aimed&nbsp; to&nbsp; evaluate&nbsp; the&nbsp; efficacy&nbsp; of&nbsp; vitamin&nbsp; E&nbsp; and&nbsp; N-acetylcysteine&nbsp; (NAC)&nbsp; on the prevention&nbsp; of&nbsp; CIN&nbsp; in&nbsp; diabetic&nbsp; patients&nbsp; undergoing&nbsp; coronary&nbsp; angiography.</p> <p><strong>Materials and</strong> <strong>Methods:&nbsp; </strong>360&nbsp; patients&nbsp; with&nbsp; diabetes&nbsp; who&nbsp; required&nbsp; angiography,&nbsp; including&nbsp; patients&nbsp; with&nbsp; stable&nbsp; angina&nbsp; susceptible&nbsp; to&nbsp; acute&nbsp; myocardial&nbsp; infarction&nbsp; and&nbsp; patients&nbsp; with&nbsp; acute&nbsp; coronary&nbsp; syndrome&nbsp; were&nbsp; included&nbsp; and&nbsp; randomized&nbsp; into&nbsp; three&nbsp; groups .&nbsp; Group&nbsp; 1&nbsp; received&nbsp; serum&nbsp; therapy&nbsp; (Normal Saline)&nbsp; plus&nbsp; NAC&nbsp; and&nbsp; placebo&nbsp; of&nbsp; vitamin&nbsp; E,&nbsp; group&nbsp; 2&nbsp; received&nbsp; serum&nbsp; therapy&nbsp; plus&nbsp; vitamin&nbsp; E&nbsp; and&nbsp; placebo&nbsp; of&nbsp; NAC,&nbsp; and&nbsp; group&nbsp; 3&nbsp; only&nbsp; received&nbsp; serum&nbsp; therapy&nbsp; with&nbsp; two&nbsp; placebos&nbsp; of&nbsp; NAC&nbsp; and&nbsp; vitamin&nbsp; E.&nbsp; The groups were compared considering CIN after angiography. <strong>Results:&nbsp; </strong>A&nbsp; total&nbsp; of&nbsp; 93&nbsp; patients&nbsp; were&nbsp; studied&nbsp; in&nbsp; group&nbsp; 1,&nbsp; 94&nbsp; in&nbsp; group&nbsp; 2,&nbsp; and&nbsp; 113&nbsp; in&nbsp; group&nbsp; 3.&nbsp; CIN&nbsp; occurred&nbsp; in&nbsp; 4&nbsp; patients&nbsp; (4.3%),&nbsp; 4&nbsp; patients&nbsp; (4.3%),&nbsp; and&nbsp; 8&nbsp; patients&nbsp; (7.1%)&nbsp; in&nbsp; groups&nbsp; 1,&nbsp; 2,&nbsp; and&nbsp; 3,&nbsp; respectively&nbsp; (P=0.58).&nbsp; There was&nbsp; a&nbsp; significant&nbsp; difference&nbsp; in&nbsp; mean&nbsp; difference&nbsp; of&nbsp; creatinine&nbsp; levels&nbsp; before&nbsp; and&nbsp; after&nbsp; study&nbsp; in&nbsp; groups&nbsp; 1&nbsp; and&nbsp; 2&nbsp; (both&nbsp; P&lt;0.001).&nbsp; In&nbsp; the&nbsp; subgroup&nbsp; of&nbsp; patients&nbsp; with&nbsp; chronic&nbsp; kidney&nbsp; disease,&nbsp; NAC&nbsp; significantly&nbsp; reduced&nbsp; CIN&nbsp; (P=0.03).</p> <p><strong>Conclusion:&nbsp; </strong>The results&nbsp; suggested&nbsp; efficacy&nbsp; of&nbsp; both&nbsp; interventions,&nbsp; considering&nbsp; reduction&nbsp; of&nbsp; mean&nbsp; Serum creatinine ( Scr) after&nbsp; the&nbsp; study,&nbsp; while&nbsp; lack&nbsp; of&nbsp; significant&nbsp; difference&nbsp; in&nbsp; the&nbsp; incidence&nbsp; of&nbsp; CIN&nbsp; could&nbsp; be&nbsp; because&nbsp; of&nbsp; the&nbsp; low&nbsp; number&nbsp; of&nbsp; CIN&nbsp; in&nbsp; our&nbsp; study.&nbsp; The second&nbsp; important&nbsp; finding&nbsp; of&nbsp; this&nbsp; study,&nbsp; probably the&nbsp; reduced&nbsp; risk&nbsp; of&nbsp; CIN&nbsp; in&nbsp; diabetic&nbsp; patients&nbsp; with&nbsp; chronic&nbsp; kidney&nbsp; disease&nbsp; receiving&nbsp; NAC,&nbsp; recommends&nbsp; the&nbsp; use&nbsp; of&nbsp; NAC&nbsp; for&nbsp; prevention&nbsp; of&nbsp; CIN,&nbsp; especially&nbsp; in&nbsp; this&nbsp; subgroup&nbsp; of&nbsp; patients&nbsp; undergoing&nbsp; angiography.</p> Mehdi Pishgahi Mahtab Niroomand Omolbanin Taziki Sepideh Shahi Kimia Karimi Toudeshki Mina Mirzaei Pirloo Copyright (c) 2021 Men's Health Journal 2021-01-14 2021-01-14 5 1 e4 e4 10.22037/mhj.v5i1.33724 Demographic Differences in Circumcision Satisfaction among U.S. Males <p><strong>Introduction: </strong>Male circumcision involves the partial or total removal of the prepuce (foreskin) from the penis, and it is the most common surgical procedure performed on infants in the USA. According to social convention theory, in demographic populations where male circumcision is more socially accepted, we would predict that circumcised men would be more likely to report satisfaction with their circumcision status. This exploratory study investigated the ways in which particular demographic sub-groups have differing attitudes and levels of satisfaction based on their circumcision status.<strong> Materials and Methods: </strong>The participant data used in these analyses are from a study conducted to explore the effects of false beliefs concerning circumcision and intact penises on circumcision satisfaction. After participant exclusion based on additional criteria, 902 male participants from the United States, ranging in age from 18-75 (<em>M</em> = 34.0, <em>SD</em> = 10.0), remained. A series of demographic information by circumcision status between participants Analysis of Variances (ANOVA) were conducted on circumcision status satisfaction. &nbsp;<strong>Results: </strong>Results indicated that circumcision status satisfaction varied as a function of race/ethnicity, religion, relationship status, and sexual orientation. Statistically significant differences in circumcision status satisfaction were found for all of the demographic variables. <strong>Conclusion: </strong>Using social convention theory, these data suggest that circumcision satisfaction is related to endorsement of the dominant culture and its norms surrounding the masculine body. Further investigation is warranted regarding causal implications of how one’s demographic characteristics may affect one’s satisfaction with their circumcision status.</p> Lauren Sardi William Jellison Copyright (c) 2021 Men's Health Journal 2021-01-27 2021-01-27 5 1 e5 e5 10.22037/mhj.v5i1.33356 Relationship Between Heavy Metal levels in Seminal Plasma and Sperm Quality in Iranian Men <p><strong>Introduction:</strong> During the last decades, frequent reports on the poor semen quality in humans have raised many researchers' concerns to study the possible impact of lifestyle or environmental factors on semen quality. The debate is continuously growing on the adverse reproductive effects of exposure to heavy and trace metals found in the environment, even at their relatively low levels. <strong>Materials and Methods:</strong> This study was carried out from July 2018 to February 2019.&nbsp; A total of 40 men were divided into two groups (idiopathic oligo– and/or asthenozoospermia and normozoospermic men) to determine the correlation between arsenic (As), cadmium (Cd), copper (Cu), and manganese (Mn) levels in the seminal plasma with sperm quality parameters including concentration, total motility, progressive motility, viability, mitochondrial membrane potential (MMP), sperm plasma membrane integrity (SPMI), acrosome integrity (AI) and DNA fragmentation in Iranian men with idiopathic oligo– and/or asthenozoospermia and normozoospermic individuals. &nbsp;<strong>Results:</strong> A significant positive or suggestive correlation was found between as concentrations in the seminal plasma and sperm concentration, motility, progressive motility, viability, MMP, SPMI, and DNA fragmentation. Moreover, seminal plasma Cd concentrations were also correlated negatively with sperm viability. We also found a positive correlation between the seminal plasma Mn levels and sperm concentration, motility, progressive motility, morphology, viability, acrosome integrity, and DNA fragmentation. <strong>Conclusion:</strong> We showed that the levels of As, Cd, and Mn levels in the seminal plasma are associated with the sperm functional parameters. Considering the unpleasant effects of the studied metals on semen quality, it is suggested that long-term contact with these metals be avoided, especially by people at their reproductive age.</p> Heidar Heidari Khoei Niloofar Ziarati Maryam Karimi Dehkordi Tohid Rezaei Tobbraghale Mohammad Javad Taher mofrad Elham Azizi Yadolah Fakhri Zahra Shams Mofarahe Copyright (c) 2021 Men's Health Journal 2021-01-24 2021-01-24 5 1 e6 e6 10.22037/mhj.v5i1.33140 Satisfaction of Patients after Urethral Reconstruction <p><strong>Introduction:</strong> Urethroplasty is one of the most common and important reconstructive procedures in the field of urology. In order to improve patient’s condition, medical man needs to be acquainted with this technique. &nbsp;We aimed to evaluate quality of life and satisfaction of patients with Urethroplasty in the reconstructive urology department of Shohada-e-Tajrish Hospital, during 1995-2016.<strong> Materials and Methods:</strong> This study was a retrospective cohort. Sampling was done by census method. The patients' demographic information, cause and duration of urethral stricture, type and frequency of procedures, daily fluid intake, urinary obstruction symptoms, the quality of marital relations, and the quality of life of patients before and after the surgery, were evaluated.<strong> &nbsp;Results:</strong> The mean age of the patients was 36.6 years. 46.4% of the patients had moderate and more than moderate marital satisfaction after surgery, while this preoperative satisfaction was 48.2% (P&gt;0.05). Patients' quality of work life and job satisfaction was significantly higher than before surgery (P=0.05). In 90.3% of the patients, urination status had no or little negative impact on their daily life after surgery. Also, 86.9% of the patients did not have weak urinary flow during follow-up. 88% of the patients were satisfied with the outcome of their surgery. Patients' satisfaction with their physical health after surgery was 82.1%.<strong> Conclusion:</strong> In general, it is inferred that Urethroplasty is associated with a high success rate and patient satisfaction, and also improves their quality of life.</p> Seyed Ali Torabi Niaki Fereshteh Aliakbari Rayka Sharifian Mohammad Ali Hosseini Jalil Hosseini Copyright (c) 2021 Men's Health Journal 2021-01-30 2021-01-30 5 1 e7 e7 10.22037/mhj.v5i1.33909 Machine Learning Approaches to predict Intra-Uterine Insemination Success Rate- Application of Artificial Intelligence in Infertility <p><strong>Introduction:</strong> Assisted Reproductive Technology (ART) has been widely utilized for infertility management. Despite its low success rate, Intra-Uterine Insemination (IUI) is one of the first alternatives and most important approaches regarding many cases of infertility treatment. Given the numerous influencing factors and limitations associated with time and resources, the development of a reliable model to predict the success rate of ART methods can significantly contribute to decision-making processes. <strong>Materials and methods:</strong> We reviewed the demographic, clinical, and laboratory data regarding 157 IUI treatment cycles among 124 women using their partner’s sperm from May2017 to June2019. Primary outcome measures were clinical pregnancy and live birth. Some prediction models were constructed and compared to the logistic regression analysis. <strong>Results</strong>: Woman’s mean age was 30.1 ± 5.2 years and the infertility had a female cause in 24.3% of the cases, male cause in 32.6% of cases, and combined causes in 32.6% of the cases. Concerning the first IUI cycle, the clinical pregnancy rate per cycle was 16.9% (N= 21). Data were prepared according to cross-industry standard&nbsp;<em>process</em>&nbsp;for data mining (CRISP-DM) methodology, and the following models were fitted to the data: J48 Decision Tree, Perceptron Multilayer (MLP) Neural Network, Support Vector Machine (SVM) with radial basis function (RBF) kernel, K-Nearest Neighbors (KNN) with one neighborhood, and Bayesian Network. J48 Decision Tree, with a sensitivity of 95% and specificity of 98%, had the most optimal performance, and the KNN model was the weakest one. <strong>Conclusion</strong>: To predict the results of IUI as a simple and less invasive therapy for infertile couples, some models were applied based on artificial intelligence and J48 Decision Tree was recommended.</p> Farzad Allameh Morteza Fallah-Karkan Shahrzad Zadeh Modarres Amir Reza Abedi Mohammad Javad Eslami Mohammad Reza Hajian Mehdi Dadpour Leyla Zareian Copyright (c) 2021 Men's Health Journal 2021-03-01 2021-03-01 5 1 e9 e9 10.22037/mhj.v5i1.34250 Prevalence of Different Subtypes of Renal Cell Carcinoma among Patients who have Undergone Nephrectomy; Statistics of a Referral Medical Center in Iran <p>Renal cell carcinoma (RCC) is the third most common genitourinary cancer in the world, and has the highest mortality rates among these types of cancers. In the present cross-sectional assessment, the prevalence of RCC subtypes in a sample of Iranian patients diagnosed with RCC which have undergone nephrectomy surgery between years 2014 to 2019 in a referral medical center has been investigated. We have studied 68 patients, including 47 male and 21 female individuals with an average age of 55. The patients have been studied for demographic and pathologic information such as age, sex, tumor size, tumor subtype, TNM staging, Fuhrman nuclear grading, and other pathological information. The statistical analysis was done via SPSS software version 21. Quantitative data were examined by T test and qualitative data were assessed by Chi square test. As we observed in the results, the most common RCC subtype among these patients was clear cell 53%, followed by papillary 22% and chromophobe 19%, emphasizing the higher rates of chromophobe RCC compared to the statistics worldwide.</p> Zahra Mohajer Afshin Moradi Farzad Allameh Copyright (c) 2021 Men's Health Journal 2021-03-01 2021-03-01 5 1 e10 e10 10.22037/mhj.v5i1.34251 The Prevalence of overweight and obesity in Iranian men: A systematic review and meta-analysis study <p><strong>Introduction:</strong> Overweight and obesity is one of the most common diseases worldwide that is less considered in men. In this regard scattered studies have been conducted in Iran, and our aim was to systematically study the prevalence of overweight and obesity in Iranian men. <strong>Methods:</strong> Major international databases including: Scopus and PubMed, and Web of Science and national databases including Magiran and SID were searched for articles in Persian and English which were published from August 10, 2010 to August 10, 2020. Qualitative evaluation of the studies was performed using the Newcastle-Ottawa Scale checklist (NOS). Random effects model was used to estimate the pooled prevalence by STATA software version 14.2 with significance level of 0.05. <strong>Results:</strong> Overall, 52 studies with a total sample size of 120,440 men with age range of 20-77 years were included in this systematic review. Most studies were conducted in 2017 and almost all of them were in Tehran province. The pooled prevalence of overweight was 46% (95% CI: 46, 46) in men. The lowest prevalence of overweight was 11.1% in Fars and the highest was 57% in Tabriz. The pooled prevalence of obesity in men was 18% (95% CI: 18, 19) with the highest prevalence in Birjand (46.5%) and the lowest in Tehran (0.8%). <strong>Conclusion:</strong> Our results showed a variety of tools for measuring overweight and obesity in Iran. Based on the BMI index, we found that the prevalence of overweight and obesity was substantial among Iranian men. There seems to be an urgent need for health policy makers to develop and implement proper preventive strategies in order to control this public health problem and its serious health consequences among men, especially in the workplace.</p> Jalil Hosseini Shahrzad Nematollahi Samira Shariatpanahi Zahra Sadegh-Zadeh Copyright (c) 2021 Men's Health Journal 2021-01-06 2021-01-06 5 1 e1 e1 10.22037/mhj.v5i1.33612 The Pooled Cut-off Point of Waist Circumference as Core Component of Metabolic Syndrome Diagnosis among the Iranian Population: a Systematic Review and Meta-Analysis <p><strong>Introduction</strong>: According to a nationwide study, one-third of the Iranian population suffer from metabolic syndrome (MetS). The most controversial criteria for the diagnosis of MetS is central obesity which would be defined by waist circumference (WC) and needed to be gender and ethnic-specific. There are several national studies that reported different cut-offs for WC so the present study aimed to do a systematic review and meta-analysis to achieve an overall statistical estimate of WC for the Iranian population. <strong>Method</strong>: A comprehensive search was conducted in international databases from inception to June 2020. The search keywords were waist circumference AND metabolic syndrome AND cut AND Iran. We used the QUADAS-2 tool for quality assessment and the HSROC model for estimating pooled specificity, sensitivity, and the cut-off point from included studies in R software. <strong>Results</strong>: A total of 3571 studies were evaluated and 24 studies fulfilled the inclusion criteria. Finally, 8 studies were included. All the studies were cross-sectional. Studies with missing MetS prevalence were excluded. Most of the studies had an unclear risk of bias in patient selection. There was a wide variation among reported cut-offs for WC from national and original studies. The Pooled cut-off points of WC for the diagnosis of MetS was 90.55 cm (95%CI: 90.51-90.60) in men and 89.24 cm (95%CI: 89.13-89.36) in women. The pooled sensitivity and specificity in men were 0.67 and 0.68, respectively and the pooled sensitivity and specificity in women were 0.61 and 0.57, respectively. <strong>Conclusion:&nbsp; </strong>Our results were highly consistent with the only national study and the only consensus about WC cut-off. Further nationwide studies are suggested to be involved in a Mata-analysis for calculating more precise WC cut-off.</p> Ehsan Shojaeefar Narges Malih Jalil Hossieni Sajjad Raeisi Alireza Esteghamati Copyright (c) 2021 Men's Health Journal 2021-02-20 2021-02-20 5 1 e8 e8 10.22037/mhj.v5i1.34149