Comparative evaluation between diameter difference of thumb and asymmetry of lateral cerebral ventricles in child with developmental delay; a new finding
Iranian Journal of Child Neurology,
Vol. 9 No. 3 (2015),
24 August 2015
How to Cite This Article: Keihanidoust Z, Shariat M, Rahimian E, Tehrani F, Saddighi Gh. Comparative Evaluation between Diameter Difference of the Thumb and Asymmetry of Lateral Cerebral Ventricles in Children with Developmental Delay: A New Finding. Iran J Child Neurol. Summer 2015;9(3):9-12.
Anthropometry (measurement of body dimensions) has been used for clinical diagnosis of growth and developmental disorders during pregnancy and after birth. Different brain volumes have also been shown in abnormal developmental disorders. This study compares the different horizontal diameters of the left- and right-hand thumbnails and asymmetry of lateral cerebral ventricles in children with developmental delays.
Materials & Methods
This retrospective case control study was carried out in the Pediatric Neurologic Outpatient of a university hospital in Tehran, Iran (2009–2011). Twenty-eight patients with motor developmental disorders (case) and 28 healthy individuals
(control) had brain MRIs and volume of lateral cerebral ventricles size had been studied. The maximum horizontal diameters of the left and right thumbnails were measured by calipers during physical and neurological exams by a pediatric neurologist. Finally, we compared and analyzed different horizontal diameters of the left and right hand thumbnails and asymmetry of lateral cerebral ventricles.
There was a significant correlation between asymmetry of brain lateral ventricles size and mean difference of horizontal diameter of thumb nails (P = 0.0001). A meaningful relation between brain hemispheres asymmetry and developmental delay (P = 0.04) was seen.
The asymmetry of thumbnails can be a marker for asymmetry of lateral ventricles and child developmental delays.
- Motor developmental delay
- Asymmetrical thumbnail size
- Asymmetry of lateral ventricles
Verbruggen KT, Meiners LC, Sijens PE, Lunsing R, Spronsen FJ, Brouwer oF. Magnetic resonance imaging and proton magnetic resonance spectroscopy of the brain in the diagnostic evaluation of developmental delay. European Journal of Paediatric Neurology.2009; 13 (2): 181-190.
Gilmore JH, van Tol JJ, Streicher HL, Williamson K, Cohen SB, Robert S. et al. Outcome in children with fetal mild ventriculomegally. A case series. Shizophernia Research 2008; 48: 219-26.
Denno N, Aurand S. Lateral preference of hand, eye and foot: relation to cerebral dominance. Int. J. Neurosci1983; 18 1(2): 1–9.
Trimarchi F, Bramanti P, Marino S, Milardi D, Mauro D, Valenti B, et al. MRI 3 D lateral ventricles in living humans: morphological and morphometrical age, gender related preliminary study. Anrta Sci In 2013; 88:61-9.
Lind A, Parkkola R, Lehtonen L, Munk P, Maunu J, Lapinleimu H, et al. Association between regional brain volumes at term-equivalent age and development at 2 years of preterm children. Pediatr Radiol 2011; 41: 953-961.
Pranab G. Dela Societed Anthropologe. De Parice Series XIII. 1974; 3- 33.
Roza SJ, Govaert PP, Vrooman HA, Lequin MH, Hofman A, Steegers E, et al. Foetal growth determines cerebral ventricular volume in infants The Generation R Study. Neuroimage 2008;39:1491-8.
Saksena SS. Facial morphometric in dentification of gene carier of X- linked hypohydropic ectodermal displasia. Am J Med Gen 1990; 35: 105- 14.
Broca P. Sur le siége de la faculté du langage articulé. Bull. Soc. Anthrop. 1865;(6):377–393.
Saliba E, Bertrand P, Gold F, Vaillant MC, Laugier J. Area of lateral ventricles measured on cranial ultrasonography in preterm infants: reference range. Arch Dis Child 1990;65:1029-32.doi:10.1136/adc.65.10_Spec_No.1029 .
Murdan S. Transverse fingernail curvature in adults: a quantitative evaluation and the influence of gender, age, and hand size and dominance. Int J Cosmet Sci 2011;33(6):509-13. doi: 10.1111/j.1468-
2011.00663.x. Epub 2011 May 25.
Scheuerle A, Ursini M. Incontinentia Pigmenti,Bloch-Sulzberger Syndrome.Initial Posting: June 8, 1999; Last Update: October 28, 2010.
Cooke RWI, Abernethy L J. Cranial magnetic resonance imaging and school performance in very low birth weight infants in adolescence. Arch Dis Child Fetal Neonatal Ed 1999;81:F116-F121 doi:10.1136/fn.81.2.F116
Leisti S., Iivanainen M. Growth, hypothalamic function, and brain ventricle size in mentally retartedsubjects. Journal of Intellectual Disability Research 1978; 22(1): 1–10.
- Abstract Viewed: 372 times
- PDF Downloaded: 179 times