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  3. Vol 15, No 3 (2022): Summer
  4. Original Article

ISSN: 2008-2258

Vol 15, No 3 (2022): Summer

Prevalence of Enteric Adenovirus Gastroenteritis and Co-infection with Rotavirus in under-Five-Year-Old Children, Qom-Iran Prevalence of Adenovirus and Co-infection with Rotavirus

  • Saeed Shams
  • Javad Tafaroji
  • Mohammad Aghaali
  • Nayebali Ahmadi
  • Hosein Heydari
  • Seyed Dawood Mousavi Nasab
  • Vineet Kumar Maurya

Gastroenterology and Hepatology from Bed to Bench, ,
https://doi.org/10.22037/ghfbb.v15i3.2483 Published 20 June 2022

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Abstract

Aim: The study was performed to determine the prevalence and co-infections with Rotavirus in children under five years of age.


Background: Gastroenteritis-associated viral infections are a cause of death among young children in Worldwide, especially in developing countries. The species F Adenovirus (40 and 41) is responsible for rang of the cases of acute diarrhea among infants children.


Methods: During 9 months, 130 children with intestinal symptoms referred to the pediatric ward of the hospital were enrolled in this study. After collecting fecal samples, viral genomes were extracted; and then amplified and typed using polymerase chain reaction by Adenovirus-specific primers. Rotavirus was detected in our previous study on the same samples and the results were used to evaluate for co-infection.


Results: Mean age of the patients was 32.09±32.68 months. 60% and 40% of the patients were males and females, respectively. Adenovirus infection was identified among 23 cases of the children (17.7%), 21 cases (91%) type 41 and 2 cases (9%) type 40. Fever was the most clinical manifestation and there were no significant relations between the clinical symptoms and the Adenovirus infection. Co-infection was found in only 5 cases (21.7%) of patients.


Conclusion: These data show that Adenovirus infection plays an important role in acute diarrheal infection in Qom. In addition, our findings indicated that there was a co-infection between Adenovirus and Rotavirus, stating a serious problem in children less than five years of age.

Keywords:
  • Adenovirus, Rotavirus, Co-infection, Gastroenteritis

How to Cite

Shams, S., Tafaroji, J., Aghaali, M., Ahmadi, N., Heydari, H., Mousavi Nasab, S. D., & Kumar Maurya, V. (2022). Prevalence of Enteric Adenovirus Gastroenteritis and Co-infection with Rotavirus in under-Five-Year-Old Children, Qom-Iran: Prevalence of Adenovirus and Co-infection with Rotavirus. Gastroenterology and Hepatology from Bed to Bench, 15(3). https://doi.org/10.22037/ghfbb.v15i3.2483
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