Endoscopic, laboratory, and clinical findings and outcomes of caustic ingestion in adults; a retrospective study
Gastroenterology and Hepatology from Bed to Bench,
Vol. 15 No. 1 (2022),
30 January 2022
https://doi.org/10.22037/ghfbb.vi.2384
Abstract
Background: With an incidence rate of 200,000 cases annually and the induction of numerous complications, caustic ingestion imposes a significant burden on the healthcare system. Apart from being mortal in some cases, this injury affects its victims’ quality of life as it is followed by many gastrointestinal problems. This injury mainly occurs accidentally among children, whereas in adults, this injury often occurs with suicidal intentions. Despite the recent advances in internal medicine, gastroenterology, and toxicology, this type of injury remains a debilitating and, in some cases, mortal disorder for its victims. Compared to the prevalence and complications, there is still limited evidence in this regard.
Materials and methods: This study retrospectively evaluated the clinical, laboratory, and endoscopic findings of 150 patients admitted to a referral center of toxicology and forensic medicine and assessed factors associated with each type of injury.
Results: we calculated a mortality rate as high as 7.3% in this population. Age, pH, and previous medical conditions were associated with more complications. Besides, higher degrees of injury were significantly associated with higher mortality, no significant difference was inspected between the types of corrosive substances.
Conclusion: It seems that the most effective intervention for controlling these types of injuries would be psychiatric support, primary health care, and household education.
- Caustic
- Clinical
- Endoscopy
- Ingestion
- Outcome
How to Cite
References
2. Ripoll Trujillo N, Martínez Sánchez L, Habimana Jordana A, Trenchs Sainz de La Maza V, Vila Miravet V, Luaces Cubells C. Ingestion of caustic substances: An analysis of the safety and benefit of a less aggressive protocol. An Pediatr. 2019 Apr 1;90(4):207–12.
3. Usta M, Erkan T, Cokugras FC, Urganci N, Onal Z, Gulcan M, et al. High doses of methylprednisolone in the management of caustic esophageal burns. Pediatrics. 2014 Jun 1;133(6).
4. Le Naoures P, Hamy A, Lerolle N, Métivier E, Lermite E, Venara A. Risk factors for symptomatic esophageal stricture after caustic ingestion-A retrospective cohort study. Dis Esophagus [Internet]. 2017 Jun 1 [cited 2020 Nov 26];30(6):1–6. Available from: https://academic.oup.com/dote/article/30/6/1/3848854
5. Struck MF, Beilicke A, Hoffmeister A, Gockel I, Gries A, Wrigge H, et al. Acute emergency care and airway management of caustic ingestion in adults: Single center observational study. Scand J Trauma Resusc Emerg Med. 2016 Apr 11;24(1).
6. Camargo MA, Lopes LR, Grangeia T de AG, Andreollo NA, Brandalise NA. Use of corticosteroids after esophageal dilations on patients with corrosive stenosis: prospective, randomized and double-blind study. Rev Assoc Med Bras. 2003;49(3):286–92.
7. Rodríguez MA, Meza Flores JL. Clinical-epidemiological characteristics in caustics ingestion patients in the Hipólito Unanue National Hospital. Vol. 23, Revista de gastroenterología del Perú : órgano oficial de la Sociedad de Gastroenterología del Perú. 2003. p. 115–25.
8. Kochhar R, Ashat M, Reddy YR, Dhaka N, Manrai M, Sinha SK, et al. Relook endoscopy predicts the development of esophageal and antropyloric stenosis better than immediate endoscopy in patients with caustic ingestion. Endoscopy. 2017 Jul 1;49(7):643–50.
9. Eskander A, Ghobrial C, Mohsen NA, Mounir B, EL-Kareem DA, Tarek S, et al. Histopathological changes in the oesophageal mucosa in Egyptia children with corrosive strictures: A single-centre vast experience. World J Gastroenterol. 2019 Feb 21;25(7):870–9.
10. M K, R W. Caustic ingestions in children. Curr Opin Pediatr. 21:651–4.
11. Ertekin C, Alimoglu O, Akyildiz H, Guloglu R, Taviloglu K. The results of caustic ingestions. Hepatogastroenterology. 2004 Sep;51(59):1397–400.
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