Gastric hepatoid adenocarcinoma with multiple liver metastasis: a case report
Gastroenterology and Hepatology from Bed to Bench,
Vol. 14 No. 3 (2021),
26 Ordibehesht 2021
,
Page 281-285
https://doi.org/10.22037/ghfbb.v14i3.2155
Abstract
Hepatoid adenocarcinoma is a poorly differentiated alpha-fetoprotein-producing (AFP) tumor frequently located in the stomach, ovary, and pancreas. Presentation in the stomach has a high mortality rate due to late diagnosis, which offers the patient few therapeutic alternatives. On February 22, 2019, a 44-year-old woman from Lima entered the emergency department for pain in the right hypochondrium for 4 months, weight loss, nausea, and asthenia. On physical examination, hepatomegaly presented with a liver spam of 17 cm. Serology showed severe anemia and AFP of 49,800. The tomography showed multiple hypodense lesions in the liver and the presence of nodes. Endoscopy showed Bormann III gastric malignancy. Gastric biopsy determined undifferentiated epithelial malignancy; the immunohistochemical mark (+) for AFP and PAS Diastase confirmed a hepatoid gastric adenocarcinoma. A rare variant of gastric adenocarcinoma was evident, which often mimics an HCC. In this case, multiple liver metastases were observed that differed from the diagnosis of HCC, so this variant must always be taken into account when a primary gastric tumor presents with hepatic metastases.
Keywords: Hepatoid adenocarcinoma, Metastases, Liver.
(Please cite as: Quino-Florentini M, Garcia-Rojas F, Guerra-Canchari P, Cerrillo-Sanchez G. Gastric hepatoid adenocarcinoma with multiple liver metastasis: a case report. Gastroenterol Hepatol Bed Bench 2021;14(3):281-285).
- Hepatoid Adenocarcinoma, metastases, liver
How to Cite
References
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