effect of a short-term physical activity after meals on gastrointestinal symptoms in individuals with functional abdominal bloating; a randomized clinical trial
Gastroenterology and Hepatology from Bed to Bench,
26 January 2021
Introduction: abdominal bloating imposes significant clinical and social and economic burden on the healthcare systems; however, treatment of bloating is limited and not effective in all individuals with this symptom. Prokinetic agents are one of those treatments recommended to be used in the treatment of bloating in individuals without underlying disorders traditionally. The present study aims to compare the effect of a short duration postprandial walking and prokinetic medications on bloating reported by healthy individuals.
Methods: the study participants were randomized into two groups of control and intervention. In control group, individuals were given daily domperidone plus activated dimethicone as a prokinetic medication. While, the subjects in the intervention group were asked to perform a 10-15 minutes of walking after each meal. The study duration was 4 weeks and afterwards the subjects were visited again and their symptoms before and after study was compared.
Results: This study consists of 94 individuals including 24 men and 70 women with mean age of 44.47 ± 12.25 years with 49 participants in control group and 45 participants in the intervention group. Both prokinetic medication use and minimal exercise after meals were associated with significant improvements in the GI tract symptoms such as belching, flatus, postprandial epigastric fullness/ bloating, gas incontinency and abdominal discomfort/pain (p-value <0.001). The changes in the score of the gastrointestinal symptoms from beginning to end of study between the two arms of study were not statistically significant except for postprandial epigastric fullness/ bloating symptoms that the intervention was superior to the control product(p-value=0.002).
Conclusion: this study shows that physical activity could be considered for relieve of abdominal bloating symptoms. In contrast to other means of treatment proposed for abdominal bloating and its related symptoms, this one needs no materials or equipment and can be performed easily by any individual.
- Abdominal bloating
- Prokinetic agents
- Physical activity
Jiang X, Locke GR, 3rd, Choung RS, Zinsmeister AR, Schleck CD, Talley NJ. Prevalence and risk factors for abdominal bloating and visible distention: a population-based study. Gut. 2008;57(6):756-63.
Talley NJ, Boyce P, Jones M. Identification of distinct upper and lower gastrointestinal symptom groupings in an urban population. Gut. 1998;42(5):690-5.
Sandler RS, Stewart WF, Liberman JN, Ricci JA, Zorich NL. Abdominal pain, bloating, and diarrhea in the United States: prevalence and impact. Digestive diseases and sciences. 2000;45(6):1166-71.
Iovino P, Bucci C, Tremolaterra F, Santonicola A, Chiarioni G. Bloating and functional gastro-intestinal disorders: where are we and where are we going? World journal of gastroenterology. 2014;20(39):14407-19.
Seo AY, Kim N, Oh DH. Abdominal bloating: pathophysiology and treatment. J Neurogastroenterol Motil. 2013;19(4):433-53.
Foley A, Burgell R, Barrett JS, Gibson PR. Management Strategies for Abdominal Bloating and Distension. Gastroenterol Hepatol (N Y). 2014;10(9):561-71.
Sullivan SN. Functional abdominal bloating with distention. ISRN gastroenterology. 2012;2012:721820.
Thompson W, Longstreth G, Drossman D, Heaton K, Irvine E, Müller-Lissner SJG. Functional bowel disorders and functional abdominal pain. 1999;45(suppl 2):II43-II7.
Johannesson E, Ringstrom G, Abrahamsson H, Sadik R. Intervention to increase physical activity in irritable bowel syndrome shows long-term positive effects. World journal of gastroenterology. 2015;21(2):600-8.
Dainese R, Serra J, Azpiroz F, Malagelada JR. Effects of physical activity on intestinal gas transit and evacuation in healthy subjects. The American journal of medicine. 2004;116(8):536-9.
Villoria A, Serra J, Azpiroz F, Malagelada JR. Physical activity and intestinal gas clearance in patients with bloating. The American journal of gastroenterology. 2006;101(11):2552-7.
Hopewell S, Hirst A, Collins GS, Mallett S, Yu L-M, Altman DGJT. Reporting of participant flow diagrams in published reports of randomized trials. 2011;12(1):253.
Keeling WF, Martin BJ. Gastrointestinal transit during mild exercise. Journal of applied physiology (Bethesda, Md : 1985). 1987;63(3):978-81.
Dainese R, Serra J, Azpiroz F, Malagelada JR. Influence of body posture on intestinal transit of gas. Gut. 2003;52(7):971-4.
Jones KL, Doran SM, Hveem K, Bartholomeusz FD, Morley JE, Sun WM, et al. Relation between postprandial satiation and antral area in normal subjects. The American journal of clinical nutrition. 1997;66(1):127-32.
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