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Vol. 4 No. 3 (2011)

June 2011

Chronic constipation: no more idiopathic, but a true neuropathological entity

  • Gabrio Bassotti
  • Vincenzo Villanacci
  • Mohammad Rostami Nejad

Gastroenterology and Hepatology from Bed to Bench, Vol. 4 No. 3 (2011), 26 June 2011
https://doi.org/10.22037/ghfbb.v4i3.163 Published: 2011-06-26

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Abstract

Chronic constipation is still considered a functional or idiopathic disorder. However, in recent years there is
evidence that its pathopysiological grounds may be actually due to a complex system of abnormalities of the
enteric nervous system of these patients. In particular, as reported in this review, the enteric glial cells seem
to be constantly involved in constipated patients, suggesting that (at least some forms of) constipation should
be considered as true neuro-gliopathies.

Keywords:
  • Constipation
  • Enteric glial cells
  • Enteric neurons
  • Enteric nervous system
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How to Cite

Bassotti, G., Villanacci, V., & Rostami Nejad, M. (2011). Chronic constipation: no more idiopathic, but a true neuropathological entity. Gastroenterology and Hepatology from Bed to Bench, 4(3). https://doi.org/10.22037/ghfbb.v4i3.163
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Print ISSN: 2008-2258
Online ISSN: 2008-4234

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