Dear Colleagues,

We would like to invite you to contribute in this special issue to improve our knowledge on gluten containing grains as major food antigens that result in coeliac disease, dermatitis Herpetiformis, wheat allergy and non-coeliac gluten sensitivity (NCGS) phenotypes. Even-though we know how systemic immune activation by increased intraepithelial T cells and cytokines react to gluten exposure, it is still unclear why the mucosal changes in coeliac disease are at such a variable range and not always correlated to the clinical presentations. This special issue has been dedicated to Professor Michael Marsh who passed away on 12 July 2021. He illuminated our insight on gluten induced pathological changes occurring within small intestine.

Professor Marsh’s fascination with coeliac disease goes back to just after first concept on coeliac disease histology when he acquired a degree in anatomy and cell biology from the University of Leeds, followed by a medical degree from the University of Oxford. His substantial contribution introduced the unique definition of remodelling of small intestinal mucosal immunopathology. This issue will focus on clinical presentation and diagnostic challenges with aspects outlined in the keyword below. We would like to cordially invite you to contribute with your original work, review and case studies to make this issue as special as before.

Manuscript Submission Information
Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published together on the special issue website. Research articles, review articles as well as short communications, case reports are invited.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Gastroenterology and Hepatology from Bed to Bench is an international peer-reviewed open access quarterly journal published by SBMU.

Please visit the Instructions for Authors page before submitting a manuscript. The accepted Articles will be published free of Charge with NO article processing charges (APC) for publication in this journal. Submitted papers should be well formatted and use good English.

Submission deadline:
January 15, 2023

Issue online release:
March 31, 2023

24 hr Support team:
Please don’t hesitate to contact the editorial office if you have any question by following email:

Coeliac disease
Non-coeliac gluten sensitivity
Follow up, clinical and histolology
Gluten threshold in CeD and NCGS. Analysis of minimal to maximal and average safety matters related to the amount of gluten intake
Gluten and Immuno-histo-genesis
Gluten Allergy
Gluten Intolerance and overlapping conditions


With best wishes

Special Issue Editors

Mihai Danciu
Professor of Anatomy Pathology
Pathology Department, Grigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania;

Kamran Rostami
Department of Gastroenterology, MidCentral Palmerston North Hospital, New Zealand