False Negative Report of 18F -FDG PET/CT in a Patient with Liver Metastases due to Uveal Melanoma
Journal of Ophthalmic and Optometric Sciences,
Vol. 5 No. 3 (2021),
15 March 2023
,
Page 37-43
https://doi.org/10.22037/joos.v5i3.40746
Abstract
Background:To report a false negative 18F-Fluorodeoxyglucose (FDG) positron emission tomography/ computed tomography (PET/CT) of liver metastasis in a patient with malignant uveal melanoma.
Material and Methods:A 74-year-old man with left eye uveal melanoma and liver metastasis that was found seven months after the enucleation surgery.
Results:Seven months post-enucleation surgery, ultrasonography revealed a suspicious hepatic lesion. Further investigation using magnetic resonance imaging (MRI) and PET scan was recommended. MRI with and without contrast reported mild post-contrast enhancement in the right lobe of the liver, suggestive of metastasis from the known tumor of the patient. 18F-FDG PET/CT surprisingly showed no metabolic evidence of malignancy throughout the body. Finally, the patient was scheduled for an ultrasound-guided biopsy. Pathology reported metastatic malignant melanoma.
Conclusion:It is important to remember not to rely solely on PET/CT since it may report false negative results in liver metastasis.
- False Negative
- 18F-FDG PET/CT
- Uveal Melanoma
- Liver Metastasis
How to Cite
References
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