Risk factors for Ahmed Glaucoma Valve (AGV) Failure in Glaucoma Patients
Journal of Ophthalmic and Optometric Sciences,
Vol. 5 No. 3 (2021),
15 March 2023
,
Page 19-24
https://doi.org/10.22037/joos.v5i3.38517
Abstract
Background: To investigate the Risk factors for AGV ( Ahmed glaucoma valve) failure.
Material and Methods: A retrospective review was conducted on the medical records of patients with varying causes of glaucoma who had undergone AGV implantation. The primary measure of success was the cumulative achievement of an intraocular pressure (IOP) between 5 and 21 mmHg, with a 20 % reduction from baseline, with or without medication to lower IOP. The secondary measures of success were the IOP levels and the number of medications used for glaucoma treatment.
Results: The study enrolled a total of 120 participants, with an average age of 48.9 ± 19.6 years and an average follow-up period of 4.5 ± 1.4 years. The mean survival duration was 5.3 ± 0.5 years in patients with high pressure (HP), which was significantly shorter than the 6.4 ± 0.2 years in those without HP. The likelihood of surgical failure increased with higher baseline IOP, with an odds ratio of 1.07 (95 % confidence interval: 1.02-1.12). In a logistic regression model, neovascular glaucoma was the only factor significantly associated with the occurrence of HP, with an odds ratio of 3.14 (95 % confidence interval: 1.2-8.1).
Conclusion :Neovascular glaucoma and a Higher Baseline IOP are risk factors for AGV failure.
- Ahmed Glaucoma Valve
- Success Rate
- Intraocular Pressure
How to Cite
References
Wilson MR, Mendis U, Paliwal A, Haynatzka V. Long-term follow-up of primary glaucoma surgery with Ahmed glaucoma valve implant versus trabeculectomy. American journal of ophthalmology. 2003;136(3):464-70.
Gedde SJ, Schiffman JC, Feuer WJ, Herndon LW, Brandt JD, Budenz DL, et al. Treatment outcomes in the Tube Versus Trabeculectomy (TVT) study after five years of follow-up. American journal of ophthalmology. 2012;153(5):789-803. e2.
Pitukcheewanont O, Tantisevi V, Chansangpetch S, Rojanapongpun P. Factors related to hypertensive phase after glaucoma drainage device implantation. Clinical Ophthalmology. 2018:1479-86.
Won HJ, Sung KR. Hypertensive phase following silicone plate Ahmed glaucoma valve implantation. Journal of Glaucoma. 2016;25(4):e313-e7.
Cheng J, Beltran-Agullo L, Buys YM, Moss EB, Gonzalez J, Trope GE. Flow test to predict early hypotony and hypertensive phase after Ahmed Glaucoma Valve (AGV) surgical implantation. Journal of Glaucoma. 2016;25(6):493-6.
Jung KI, Park CK. Risk factors for the hypertensive phase after implantation of a glaucoma drainage device. Acta Ophthalmologica. 2016;94(5):e260-e7.
Tsai JC, Johnson CC, Kammer JA, Dietrich MS. The Ahmed shunt versus the Baerveldt shunt for refractory glaucoma II: longer-term outcomes from a single surgeon. Ophthalmology. 2006;113(6):913-7.
Christakis PG, Kalenak JW, Tsai JC, Zurakowski D, Kammer JA, Harasymowycz PJ, et al. The Ahmed versus Baerveldt study: five-year treatment outcomes. Ophthalmology. 2016;123(10):2093-102.
Budenz DL, Feuer WJ, Barton K, Schiffman J, Costa VP, Godfrey DG, et al. Postoperative complications in the Ahmed Baerveldt comparison study during five years of follow-up. American journal of ophthalmology. 2016;163:75-82. e3.
Ayyala RS, Zurakowski D, Monshizadeh R, Hong C-H, Richards D, Layden WE, et al. Comparison of double-plate Molteno and Ahmed glaucoma valve in patients with advanced uncontrolled glaucoma. Slack Incorporated Thorofare, NJ; 2002. p. 94-9.
Lee J, Park CK, Jung KI. Initial glaucoma medication in the hypertensive phase following Ahmed valve implantation: A comparison of results achieved using aqueous suppressants and prostaglandin analogs. Journal of Clinical Medicine. 2020;9(2):416.
Jung KI, Park H, Jung Y, Park CK. Serial changes in the bleb wall after glaucoma drainage implant surgery: characteristics during the hypertensive phase. Acta ophthalmologica. 2015;93(4):e248-e53.
Hou Xr, Miao H, Tao Y, Li Xx, Wong IY. Expression of cytokines on the iris of patients with neovascular glaucoma. Acta Ophthalmologica. 2015;93(2):e100-e4.
- Abstract Viewed: 79 times
- pdf Downloaded: 51 times