Advances in Nursing & Midwifery

Vol. 24 No. 85 (2015)

Relationship between maternal serum C - reactive protein

Advances in Nursing & Midwifery, Vol. 24 No. 85 (2015), 2 July 2015 , Page 31-38
https://doi.org/10.22037/anm.v24i85.8111

Abstract

Abstract 

Abstract Background:

 It is hypothesized that GDM may be a systemic inflammation mediated by cytokine.

This case-control study was designed to investigate correlation between C-reactive protein (CRP) and

 gestational diabetes mellitus (GDM).

 Method:

 In a case-control study, a convenient sample of 60 pregnant women with GDM (case group) and

120 pregnant women without GDM (control group) who attended to GDM and prenatal clinics and women

 

clinics of Ayatollah Taleghani and Mahdiyeh Hospitals were included. Serum level of CRP measured by

 

qualitative and quantitative methods was compared in two groups. Demographic information and

 

reproductive history were obtained by interview. Both of the group was matched in age, parity, first trimester

 body mass index and DMF index. Data were analyzed by descriptive and analytic statistics.

 Result

 : Demographic characteristics and reproductive histories were similar in two groups. Significantly

different was between two groups in serum level of qualitative CRP (p<0/0005) and serum level of

 quantitative CRP (P<0/0005). CRP was strongly associated wish Glucose Challenge Test (GCT) (p<0/0005).

 Conclusion

 : The results suggest that there is correlation between C-reactive protein and gestational diabetes

mellitus, and inflammation may play an important role in the development of gestational diabetes mellitus and

 CRP can act as the risk predictor of GDM. More studies are needed to verify these results.

 Key words:

 Gestational Diabetes, C - reactive protein, Pregnancy

 

 

Keywords:
  • Gestational Diabetes
  • C - reactive protein
  • Pregnancy

How to Cite

Ahi, zahra, Kariman, norosadat, Zahedi, saleh, & Shakeri, nezhat. (2015). Relationship between maternal serum C - reactive protein. Advances in Nursing & Midwifery, 24(85), 31–38. https://doi.org/10.22037/anm.v24i85.8111

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