Archives of Advances in Biosciences <p><strong><em>Archives of Advances&nbsp;in Biosciences </em></strong><strong>(AAB) </strong>is an open access, peer-reviewed, and continuous journal published by Shahid Beheshti University of Medical Sciences. <em>AAB</em> is committed to rapid, fair, and transparent publication of valuable research from diverse areas of biosciences.</p> <p><em>AAB</em> welcomes the submission of Research Articles, Short Reports, Research Advances, Scientific Correspondence, and Review Articles in the areas below:</p> <p>Medical Basic Sciences</p> <p>Immunology/ Cancer</p> <p>Epidemiology/Biochemistry</p> <p>Pharmacology/Genetic &nbsp;</p> en-US <p><strong>Copyright</strong><br>The Archives of Advances in Biosciences (AAB) is published under the Creative Commons Attribution License. Under this certificate, the journal allows the subscription, matching and assignment of published articles.</p> <p><strong>Intellectual Property</strong><br>Intellectual Property Rights: Open Access Journal becomes aware of breaches of our publication ethics policies, whether or not the breach occurred in a journal published by Intellectual Property Rights: Open Access Journal, the following sanctions may be applied across the Intellectual Property Rights: Open Access Journal :<br>•&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Rejection of the manuscript and any other manuscripts submitted by the author(s).<br>•&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Not allowing submission for 1–3 years.<br>•&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Prohibition from acting as an editor or reviewer.<br>Investigations<br>Suspected breaches of our publication ethics policies, either before or after publication, as well as concerns about research ethics, should be reported to our Research Integrity team.<br><br>Claimants will be kept anonymous. Intellectual Property Rights: Open Access Journal may ask the authors to provide the underlying data and images, consult editors, and contact institutions or employers to ask for an investigation or to raise concerns.<br><br><strong>Corrections and retractions</strong><br><br>When errors are identified in published articles, the publisher will consider what action is required and may consult the editors and the authors’ institution(s). Errors by the authors may be corrected by a corrigendum and errors by the publisher by an erratum. If there are errors that significantly affect the conclusions or there is evidence of misconduct, this may require retraction or an expression of concern following the&nbsp;AAB&nbsp;Retraction Guidelines. All authors will be asked to agree to the content of the notice.</p> <p><strong>Post-Publication</strong></p> <p><strong>&nbsp;Post-Publication matters at AAB</strong><br><br>We do respectfully invite authors, co-authors, reviewers, and our valuable readers to please advise us on any published matters, including its layout, format, texts, figures, and tables, and most importantly the subject, and content at any sections of a manuscript, especially the results and discussion, as well as the conclusions. Please email us at:&nbsp;<a href=""></a>&nbsp;or&nbsp;<a href=""></a>&nbsp;with the copy of the manuscript DOI number as the subject line of your email.<br>The section editor of the published article will review your comments and discuss them with the corresponding author and peer reviewers, if required. The final result of these investigations will be discussed with the editor-in-chief to make the best action. It might be in a range of a logical private reply to you, publishing of a note, or a short communication on that article at the journal, correction of parts of the article with or without public announcement, and in some very exceptional circumstances the removal of the article from&nbsp;AAB. An email listing all considerations and criteria for the final decision will be sent to the corresponding author and the reviewers. If required, the matter will be published at the&nbsp;AAB&nbsp;journal for public notice.</p> (Dr. Hamid Chegni) (Dr. Tahereh Hadadi; Executive Editor) Sun, 19 Feb 2023 00:00:00 +0000 OJS 60 Evaluation Of Response Inhibition In The Face Of Cognitive And Emotional Stimuli In Patients With Frontal Lobe Tumors Before And After Surgery <p><strong>Introduction:</strong> The functions of specialized brain parts undoubtedly influence emotional inhibition. Numerous studies have considered the prefrontal cortex of the brain’s two hemispheres to be responsible for this behavior. However, few studies have addressed the question of to what degree a change in this brain unit can affect response inhibition and reaction time in the face of emotional stimuli. Therefore, the current study aimed to investigate emotional behavior in patients with frontal lobe gliomas.</p> <p><strong>Materials and Methods</strong>: In this research, the Integrated Visual and Auditory (IVA) test and affective Go/No-Go task in the areas of happiness and anger, focusing on response accuracy and reaction time were performed for sixteen patients with frontal lobe lesions and twenty healthy individuals. These tests were repeated three months after surgery.</p> <p><strong>Results:</strong> The results revealed that following surgery, an improvement in the patients’ reaction times and response accuracy to both emotional stimuli especially against the stimulus of anger exist. The IVA results showed the significant improvement in neurocognitive condition of all patients following surgery.</p> <p>&nbsp;<strong>Conclusion:</strong> The findings of this research revealed that toward improving the emotional conditions, lesion resection surgery could significantly help these patients regain their normal cognitive function. However, still, a difference was between patients and healthy individuals.</p> Zahra Farshidfar, Mohamad-ali Oghabian, Mehdi Tehrani-Doost, Seyed AmirHossein Javadi Copyright (c) 2023 Archives of Advances in Biosciences Mon, 29 May 2023 10:12:04 +0000 Feline Mammary Carcinomas as a Model for Human Breast Cancer: A Case-series Study <p><strong>Introduction:</strong> Feline mammary carcinoma (FMC) is the third most common cancer in cats. Diagnosis of mammary gland tumors (MGTs) increases every year; this might be due to the rise in occurrence or improvements in methods of detecting MGTs. Determinants associated withtheir occurrence are studied in the present paper.</p> <p><strong>Materials and Methods: </strong>In this case-series study, 40 queens with FMC were referred to the determined major veterinary hospitals of Tehran for treatment between 2020 and 2022; their mammary carcinoma had been confirmed by the attended pathologist. Different parameters including age of cancer diagnosis, breed, reproductive status, BCS, diet type, parity, tumor size, multiple tumors, ER and PR status, location and type of treatment were recorded on the day of presentation using a checklist.</p> <p><strong>Results: </strong>Domestic short hairs were overrepresented. Also, queens with old age (more than 9 years old), homemade diet, sexually intact status, no parity, obesity, ER and PR positivity had higher frequency towards developing FMC. Imbalanced homemade diet energy is a speculated cause.</p> <p><strong>Conclusion: </strong>Humans and their companion animals share the same environment, thus being exposed to the same environmental risks. Although canine mammary tumors have been the focus of human breast cancer (HBC) modeling, this study also aimed to compare current feline mammary carcinoma determinants with previously defined human breast cancer determinants to produce a model. Based on the results of this study, we concluded that FMCs are a proper model to study HBC.</p> Kiavash Hushmandi, Saied Bokaie, Darioush Shirani, Ali Taghipour Copyright (c) 2023 Archives of Advances in Biosciences Wed, 29 Mar 2023 00:00:00 +0000 Evaluation of Lipid Profile, Apo B/ Apo A Ratio and Lpa and its Relationship with Cognitive Disorders in the Older Adults: Birjand Longitudinal Aging Study <p><strong>Introduction: </strong>Accurate and timely diagnosis of mild cognitive disorders is essential to prevent their progression to dementia. This study aimed to determine the relationship among the serum levels of lipid markers of cognitive disorders in older adults in Birjand.</p> <p><strong>Materials and Methods: </strong>The community-based cohort study was performed on 1400 older adults population (60 years and older) living in urban and rural areas of Birjand, among whom 242 older adults were selected by multi-stage random sampling; the Mini-Mental State Examination Cognitive Disorders Questionnaire was completed, and five cc of blood samples were taken to assess Triglyceride, Cholesterol, Low density lipoprotein, High-density lipoprotein, lipoprotein a, Apo lipoprotein A, and Apo lipoprotein B.</p> <p><strong>Results: </strong>The mean age of participants was 70.6± 6.96 years. 55.4% were women. The level of MMSE was significantly different based on the demographic information. Mean serum levels of Lipid profile, Apo B/ Apo A Ratio, and LP a, were not significantly different from MMSE.</p> <p><strong>Conclusion: </strong>The study showed a significant relationship between demographic information and MMSE level, so it can be used to improve the cognitive level of older adults by changing their life situation, marital status, and education. However, the parameters of Lipid profile, Apo B/ Apo A Ratio, and LP a are not used to diagnose cognitive disorders in older adults.</p> Sara Hamdamian, Asghar Zarban , Mitra Moodi, Farshad Sharifi, rasoul raesi, Mohammad Dehghani Firoozabadi Copyright (c) 2023 Archives of Advances in Biosciences Thu, 16 Mar 2023 00:00:00 +0000