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Prevalence of Infertility In Iran: A Systematic Review And Meta-Analysis

Marzieh Saei Ghare Naz, Giti Ozgoli, Koroush Sayehmiri



Purpose: In the present study, a systematic review and meta-analysis was conducted to determine the prevalence of infertility in Iran.

Materials and Methods: A search of studies was conducted in June 2019 based on the electronic method, across databases such as Scopus, PubMed, Web of Science (WOS), Scientific Information Database (SID), Magiran, Irandoc and Google scholar. The study used the keywords related to the infertility. The search for articles was limited to the recent 20 years published articles with Persian and English language. In this study only population based studies were included.  The data was analyzed using the STATA software 11.1. In this study, the random-effects model is considered, when there is heterogeneity among the studies (I2>50%).

Results: The results of the analysis showed that the overall prevalence of infertility in was 7.88%, 95% CI: 5.61-10.51%, Q=323.63, p<.001. The current primary infertility prevalence after sensitivity analyzes was 3.09%, 95% CI: 2.27-4.02%, Q=245.14, p<.001. The secondary infertility prevalence after sensitivity analyzes was 2.18%, 95% CI: 1.56-2.89%, Q=150.92, p<.001. The rising slope of the meta regression line showed that the prevalence of primary (p=.7), and secondary infertility (p=.4), based on year in Iran is rising with a slow slop and overall prevalence decrease (p=.7).

Conclusion: It is emphasized that the results of this study are related to the areas where studies have been conducted and there are high hetrogenity. Given that information is not available in all parts of Iran, a population-based study, or the design and implementation of studies that are not carried out, are suggested


Infertility, Iran, Prevalence, Meta-analysis.



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DOI: http://dx.doi.org/10.22037/uj.v0i0.5610


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