Extra-renal Transplanted Kidney Stone: Case Presentation and Literature Review

Abbas Basiri, Mohammad Nadjafi Semnani, Hamed Mohseni Rad



Soft tissue calcification is common in uremic patients. Wound calcification or ossification is not so prevalent except in specific conditions like inflammation and ischemia or wound tension. We present a 40-year-old transplanted patient, not only perirenal ossification but also with multiple perirenal stones. The presentation was severe pain on the site of transplantation. Pre-op CT scan revealed perirenal calcified mass. Intraoperative finding was very
thick tissue accompanied with a lot of stones around the transplanted kidney. The patient had history of ureteral fistula after renal transplantation that needed temporary percutaneous nephrostomy and then uretero-neocystomy.
It seems that urinary leakage through nephrostomy site probably is the predisposing factor for stone formation around the kidney where as there is no stone inside the Kidney.

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Kim J, Kim Y, Jeong WK, and et al. Heterotopic ossification developing in surgical incisions of the abdomen: analysis of its incidence and possible factors associated with its development. J Comput Assist Tomogr. 2008;32:872–6

Alfrey AC, Solomons CC, Ciricillo J, Miller NL. Extraosseous calcification. Evidence for abnormal pyrophosphate metabolism in uremia. J Clin Invest 1976;57:692-9

Labidi J, Ariba YB, Gabsia AB, Ajili F, Battikh R, Louzir B, et al. Severe metastatic calcifications in a hemodialysis patient. Saudi J Kidney Dis Transpl 2016;27:1037-42

Peled I, Bar-Lev A, Wexler M. Subcutaneous calcifications of the lower limbs. Ann Plastic Surg 1982; 8:310-3

Sunquist A, Kurien A, Duke M. Subcutaneous calcification of the legs in chronic venous insufficiency. Connecticut Med 1966; 30:41-2.

Walsh J, Fairley J. Calcifying disorders of the skin. [Continuing Medical Education] J Amer Acad Dermatol 1995; 33:1-28.

Richard J. Brietstein, E. David Sonkin, Charles Jason Hubbard. Nonhyperparathyroid Wound Calcifications: Two Case Presentations and Literature Review. WOUNDS. 2002; 14:136-41.

Burkhart CG, Burkhart CN, Mian A. Calciphylaxis: A case report and review of literature. Wounds 1999; 11:58-61.

Touart D, Sau P. Cutaneous deposition diseases, part II. [Continuing Medical Education] J Amer Acad Dermatol 1998;39:1-34.

Sanders BP, Orlando G, Peloso A, Katari RS, Iskandar SS, Farney AC,et al.Osseus metaplasia in kidney allografts as a paradigm of regenerative medicine principles. Exp Clin Transplant. 2014 Aug; 12:371-3.

Asami G, Dock W. Experimental studies on heteroplastic bone formation. J Exp Med. 1920; 32:745-66.

Doherty MJ, Ashton BA, Walsh S, et al. Vascular pericytes express osteogenic potential in vitro and in vivo. J Bone Miner Res. 1998; 13:828–838.

DOI: http://dx.doi.org/10.22037/uj.v0i0.3842

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