Association of Serum Fetuin-A Levels with Allograft Outcome in Renal Transplant Recipients
Urology Journal,
Vol. 12 No. 3 (2015),
1 July 2015
,
Page 2182-2186
https://doi.org/10.22037/uj.v12i3.2788
Abstract
Purpose: To determine serum fetuin-A pattern after renal transplantation and its association with graft outcome.
Materials and Methods: In 41 renal transplant recipients, serum pretransplant fetuin-A levels and serum fetuin-A concentrations on days 7 and 30 after transplantation were measured using the enzyme-linked immunosorbent assay (ELISA) method. Also, the association between serum fetuin-A levels with clinical and laboratory parameters was evaluated.
Results: A significant decrease in serum fetuin-A levels was noted in the first week after transplantation (P < .001). Subsequently, it started to increase and surpass pretransplant values during the first month (P < .001). Pretransplant fetuin-A levels did not differ among patients with different diethylenetriamine pentaacetic acid (DTPA) results. In addition, serum fetuin-A levels did not significantly correlate with metabolic parameters.
Conclusion: In this prospective study there was no increase in serum fetuin-A levels during the first month and pretransplant fetuin-A levels are not predictive for allograft outcome in renal transplant recipients.
How to Cite
- Abstract Viewed: 310 times
- PDF Downloaded: 180 times