Phage Therapy as a New Approach in Treating Emerging Antibiotic Resistant Infections

Ramak Ajideh, Mohammad Ali Faramarzi, Mohammad Hossein Yazdi, Mohammad Reza Pourmand

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Abstract

Despite the progress in treatment of infectious diseases, ability of microorganisms to develop the resistance to routine antibiotics has still remained as a big global challenge in clinics. This subject matter keeps the infections top in the list of life threatening diseases especially in those individuals suffering from nosocomial infections. The importance of this global health challenge urges researchers to find an alternative solution with more efficacies to treat infections. There are some alternative approaches by which the global spread of resistant bacteria could be controlled. Through these ways, using bacteriophages instead of different generation of antibiotics brings many promises. According to results of different studies using bacteriophages in the management of infectious disease especially in nosocomial infections not only helps to reduce the spread of antibiotics resistance but also raises the hopes for the rescue of the suffering patients. Bacteriophages can open a new therapeutic window in the control and the treatment of the infectious disease with better efficacy.


HIGHLIGHTS
•Bacteriophage can be used as an antimicrobial agent for treatment of bacterial infection.
•Bacterial resistance to routine antibiotics is a big challenge in the world.
•Specificity toward bacteria is one of the important characteristic of phages.

Keywords

Bacterial resistance; Nosocomial Infections; Bacteriophage Therapy; Alternative approach; Natural phage; Synthetic phages

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References

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