• Logo
  • SBMUJournals

A Young Immunocompetent Cytomegalovirus Retinitis Patient

Rahim Naseri, Shahnaz Sali, Anita Yazdani, Salime Peyghan






Background: Rare cases if CMV retinitis were presented in immunocompetent patients (Nine cases)

Cases Report: A 23 years old man with chief complain of sudden decrease of visual acuity and floater in left eye was under investigation. He was immunocompetent patient without any human immunodeficiency virus and immunosuppression diseases. He was diagnosed as a case of cytomegalovirus retinitis and was treated by intraviteral Ganciclovir. His choroid retinitis was improved after treatment.

Conclusion: in retinal vasculitis before approaching anti-inflammatory or anti-VEGF therapy ophthalmologists should take into account infectious causes.


CMV, Retinitis, HIV, Ganciclovir, Macula


Panel on Opportunistic Infections in HIV-Infected Adults and Adolescents. Guidelines for the prevention and treatment of opportunistic infections in HIV-infected adults and adolescents: Recommendations from the Centers for Disease Control and Prevention, the National Institutes of Health, and the HIV Medicine Association of the Infectious Diseases Society of America. http://aidsinfo.nih.gov/contentfiles/lvguideline s/adult_oi.pdf (Accessed on November 04, 2015)

Arevalo JF, Garcia RA, Mendoza AJ. High-dose (5000-microg) intravitreal ganciclovir combined with highly active antiretroviral therapy for cytomegalovirus retinitis in HIV-infected patients in Venezuela. Eur J Ophthalmol 2005; 15:610.

Teoh SC, Ou X, Lim TH. Intravitreal ganciclovir maintenance injection for cytomegalovirus retinitis: efficacy of a low-volume, intermediate-dose regimen. Ophthalmology 2012; 119:588.

Jabs DA, Van Natta ML, Kempen JH, et al. Characteristics of patients with cytomegalovirus retinitis in the era of highly active antiretroviral therapy. Am J Ophthalmol. Jan 2002; 133(1):48-61. Available at http://www.ncbi.nlm.nih.gov/pubmed/11755839

Kedhar SR, Jabs DA. Cytomegalovirus retinitis in the era of highly active antiretroviral therapy. Herpes. 2007; 14:66–71. [PubMed]

Gupta Seema, Vemulakonda G.A. Cytomegalovirus retinitis in the absence of AIDS. Can J Ophthalmol. APRIL 2013; 48.

Miyamoto K., Hiroshiba N., Tsujikawa A. In vivo demonstration of increased leukocyte entrapment in retinal microcirculation of diabetic rats. Invest Ophthalmol Vis Sci. 1998; 39:2190–2194.

Saidel M.A., Berreen J., Margolis T.P. Cytomegalovirus retinitis after intravitreous triamcinolone in an immunocompetent patient. Am J Ophthalmol. 2005; 140:1141–1143.

Vertes D, Snyers B, DePotter. Cytomegalovirus retinitis after low-dose intravitreous triamcinolone acetone in an immunocompetent patient: a warning fotr the widespread use of intravitreal corticosteroids. Int Ophthalmol 2010; 30 (5): 595-7.

Schneider EW, Elner SG, van Kuijk FJ, et al. Chronic Retinal Necrosis: Cytomegalovirus necrotizing retinitis associated with panretinal vasculopathy in non-HIV patients. Retina 2013; 33 (9): 1791-9.

Print: Wills Eye Manual. Sixth Edition. Section 12.9: Cytomegalovirus Retinitis. Philadelphia, PA: Lippincott Williams & Wilkins; 2012.

DOI: https://doi.org/10.22037/nbm.v7i1.21845