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Investigation of Antibacterial Effect of Cuminum cyminum and Carum carvi against Streptococcus mutans and Streptococcus pyogenes

Mona Ghazi, Hossein Goudarzi, Hamidreza Ataee Zadeh Ardekani, Maliheh Habibi, Eznolla Azargashb, Bahareh Hajikhani, Mehdi Goudarzi
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Abstract

Background: Streptococcus mutans is major cause of tooth decay. In addition, there is some report about effects of Streptococcus pyogenes on odontogenic infections. Herbal drugs is now administrating for treatment of some disease. The aim of this study was to evaluate the antibacterial effect of Cuminum cyminum and Carum carvi against Streptococcus mutans and Streptococcus pyogenes.

Materials and Methods: In this study, standard strains of Streptococcus mutans and Streptococcus pyogenes were used, and ethanolic extract was prepared in the microbiological laboratory of Shahid Beheshti University of Medical Sciences. The experiment was repeated 6 times and chlorohexine 2% was used as a control.

Results: The best effect of Carum carvi was on Streptococcus mutans, whereas on Streptococcus pyogenes both extracts of Cuminum cyminum and Carum carvi showed the same effect.

Conclusion: This study showed, due to the fact that the Cuminum cyminum and Carum carvi extracts exhibited excellent antibacterial properties, they could be a suitable candidate in compounds such as mouthwash, toothpastes and Gums. Therefore, could be used in the prevention and treatment of future oral and dental diseases.


Keywords

Cuminum cyminu, Cuminum cyminum, Streptococcus mutans and Streptococcus pyogenes

References

Aas JA, Paster BJ, Stokes LN, Olsen I, Dewhirst FE. Defining the normal bacterial flora of the oral cavity. Journal of clinical microbiology. 2005;43(11):5721-32.

Kreth J, Merritt J, Shi W, Qi F. Competition and coexistence between Streptococcus mutans and Streptococcus sanguinis in the dental biofilm. Journal of bacteriology. 2005;187(21):7193-203.

Forssten SD, Björklund M, Ouwehand AC. Streptococcus mutans, caries and simulation models. Nutrients. 2010;2(3):290-8.

Inagaki Y, Abe M, Inaki R, Zong L, Suenaga H, Abe T, et al. A Case of Systemic Infection Caused by Streptococcus pyogenes Oral Infection in an Edentulous Patient. Diseases. 2017;5(3):17.

Bessen DE. Population biology of the human restricted pathogen, Streptococcus pyogenes. Infection, Genetics and Evolution. 2009;9(4):581-93.

Loesche WJ. Microbiology of dental decay and periodontal disease. 1996.

Newton SM, Lau C, Gurcha SS, Besra GS, Wright CW. The evaluation of forty-three plant species for in vitro antimycobacterial activities; isolation of active constituents from Psoralea corylifolia and Sanguinaria canadensis. Journal of ethnopharmacology. 2002;79(1):57-67.

Davidson-Hunt I. Ecological ethnobotany: stumbling toward new practices and paradigms. MASA J. 2000;16:1-13.

Atrooz OM. The effects of Cuminum cyminum L. and Carum carvi L. seed extracts on human erythrocyte hemolysis. International Journal of Biology. 2013;5(2):57.

Zargari A. Medicinal plants: Tehrari University Publications. ISBN; 1995.

Rai N, Yadav S, Verma A, Tiwari L, Sharma RK. A Monographic Profile on Quality Specifications for a Herbal Drug and Spice of Commerce-Cuminum cyminum L. International Journal of Advanced Herbal Science and Technology. 2012;1(1):pp. 1-12.

Basri DF, Fan S. The potential of aqueous and acetone extracts of galls of Quercus infectoria as antibacterial agents. Indian journal of Pharmacology. 2005;37(1):26.

Gür D. Clinical and Laboratory Standards Instıtute (CLSI). Antimikrobik Duyarlılık Testleri İçin Uygulama Standartları. Onbeşinci Bilgi Eki. M100-S14; 2008.

Soleymani N, Sattari M, Sepehriseresht S, Daneshmandi S, Derakhshan. Evaluation of reciprocal pharmaceutical effects and antibacterial activity of Bunium persicum essential oil against some Gram positive and Gram negative bacteria. Iranian Journal of Medical Microbiology. 2010;4(1):26-34.

Safari R, Adel M, Monji H, Riyahi Cholicheh H, Nematolahi A. Evaluation of antibacterial effect of some of the endemic herbal essential oils on Streptococcus iniae in invitro. Journal of Aquatic Ecology. 2015;4(4):40-33.

Aali E, Mahmoudi R, Kazeminia M, Hazrati R, Azarpey F. Essential oils as natural medicinal substances: review article. Tehran University Medical Journal. 2017;75(7):480-9.

Oroojalian F, Kasra-Kermanshahi R, Azizi M, Bassami M. Synergistic antibacterial activity of the essential oils from three medicinal plants against some important food-borne pathogens by microdilution method. Iranian Journal of Medicinal and Aromatic Plants. 2010;26(2):133.




DOI: https://doi.org/10.22037/nbm.v7i1.19389