• Logo
  • SBMUJournals

Investigation of Leukemia Frequency in Children of Qazvin Province and its Correlation with Gender, Age, and Blood Groups between 2006-2016

Tahere Dargahi, Mehdi Goudarzi, Naser Mobarra, Hoda Poorkarim, Sajjad Rahmani, Mojtaba Khalili, Mehran Amini, Javad Hamedani, Mehdi Azad
463

Views

PDF

Abstract

Background: About 8 percent of all cancers in human population are related to leukemia and it is one of the most common malignancies in children. The aim of this study was to compare the prevalence of age, gender and blood group types with the frequency of leukemia among the children with leukemia in Qazvin province during the 2006 to 2016.

Materials and Methods: This was a cross-sectional analysis. Investigated population was 110 children and adolescents under 18 years in the hospitals of Qazvin province. The date collecting method was through review of medical records of the patients and their analysis performed by using SPSS version 16.

Results: According to data from this study, leukemia ALL-L1 is more frequent in Qazvin than other types of leukemia, and children with ages 0-5 years was more than other age groups. This disorder is more common in boys than girls, and among the patients, the people who has A and O blood groups, and Rh + are the most abundant.

Conclusion: such factors like age, gender and blood groups can use as prognostic factors in children leukemia. So that leukemia in children less than 5 years old is more than any other age. In addition to that; the incidence of leukemia ALL-L1 reduced with increasing age in the general population in Qazvin and number of boys with leukemia is more than girls.


Keywords

leukemia, children, frequency, blood group

References

Pahloosye A, Hashemi AS, Mirmohammadi SJ, Atefi A. Presenting Clinical and Laboratory Data of Childhood Acute Lymphoblastic Leukemia. Iranian journal of Pediatric Hematology Oncology. 2011;1(3):71-7.

Linet M, Devesa S. Descriptive epidemiology of childhood leukaemia. British journal of cancer. 1991;63(3):424.

Sakic M. Distribution of ABO blood group in children with acute leukemias. Journal of Health Sciences. 2012;2(3).

Babu KLG, Doddamani GM, Mathew J, Jagadeesh KN, Naik LRK. Pediatric leukemia. Journal of Pediatric Dentistry. 2015;3(1):8.

Group UCSW. Incidence and mortality web-based report. Atlanta: Department of Health and Human Services; 2009.

Jemal A, Thun MJ, Ries LA, Howe HL, Weir HK, Center MM, et al. Annual report to the nation on the status of cancer, 1975–2005, featuring trends in lung cancer, tobacco use, and tobacco control. Journal of the National Cancer Institute. 2008;100(23):1672-94.

Mossoomy Z, Mesgari M. Detection of leukemia epidemiology in Iran using GIS and statistical analyses. Pediatric Hematology and Oncology. 2008;32:441-8.

Belson M, Kingsley B, Holmes A. Risk factors for acute leukemia in children: a review. Environmental health perspectives. 2007:138-45.

Fauci AS. Harrison's principles of internal medicine: McGraw-Hill Medical New York; 2008.

Elliot P, Wakefield JC, Best NG, Briggs D. Spatial epidemiology: methods and applications: Oxford University Press; 2000.

Health UDo, Services H. Agency for toxic substances and disease registry. Toxicological Profile for Asbestos Update Agency for Toxic Substances and Disease Registry. 1999.

Malphettes M, Gérard L, Carmagnat M, Mouillot G, Vince N, Boutboul D, et al. Late-onset combined immune deficiency: a subset of common variable immunodeficiency with severe T cell defect. Clinical Infectious Diseases. 2009;49(9):1329-38.

Alrudainy L, Mahmood Salih H, Mohammed A. Incidence and pattern of childhood leukaemia in Basrah, Iraq during 2003− 2007. Iran J Blood Cancer. 2009;2:11-7.

Katz AJ, Chia VM, Schoonen WM, Kelsh MA. Acute lymphoblastic leukemia: an assessment of international incidence, survival, and disease burden. Cancer Causes & Control. 2015;26(11):1627-42.

Tavasolian F, Abdollahi E, Vakili M, Amini A. Relationship between ABO blood group and Acute Lymphoblastic Leukemia. Iranian journal of pediatric hematology and oncology. 2014;4(1):1.

Deschler B, Lübbert M. Acute myeloid leukemia: epidemiology and etiology. Cancer. 2006;107(9):2099-107.

Gurney JG, Davis S, Severson RK, Fang J-Y, Ross JA, Robison LL. Trends in cancer incidence among children in the U. S. Cancer. 1996;78(3):532-41.

Liu Y-L, Lo W-C, Chiang C-J, Yang Y-W, Lu M-Y, Hsu W-M, et al. Incidence of cancer in children aged 0–14 years in Taiwan, 1996–2010. Cancer epidemiology. 2015;39(1):21-8.

Farhud D, Sadighi H, Andonian L, Saffari M, Poursadegh Fard M, et al. Study of Sex Ratio, Abo and Rh Blood Groups Distribution In Some Haematological And Lymphatic Diseases In Iran. Iranian Journal of Public Health. 1995;24:1-2.

Vadivelu MK, Damodaran S, Solomon J, Rajaseharan A. Distribution of ABO blood groups in acute leukaemias and lymphomas. Annals of hematology. 2004;83(9):584-7.

Alavi S, Ashraf H, Rashidi A, Hosseini N, Abouzari M, Naderifar M. Distribution of ABO blood groups in childhood acute leukemia. Pediatric hematology and oncology. 2006;23(8):611-7.

Shirley R, Desai R. Association of leukaemia and blood groups. Journal of medical genetics. 1965;2(3):189.

Steinberg AG, Steinfeld JL. The genetics of acute leukemia in children. Cancer. 1960;13(5):985-99.

Nagy P, Jako J, Kiss A, Tamas E, Telek B, Rak K. Sex‐Linked Difference in Blood‐Group Distribution among Patients Suffering from Acute Leukaemias. British journal of haematology. 1981;48(3):507-12.




DOI: https://doi.org/10.22037/nbm.v4i4.14670