Association between ELF and RF electromagnetic field and Leukemia

Majid Mahdavi, Reza Yekta, Saeed Hesami Tackallou



     Extremely low frequency (ELF) electromagnetic field (ELF-EMFs) are widely employed in electrical appliances and different equipment such as television sets, ELF-EMFs can  affect biological systems by increasing production  ROS. The altered balance between ROS generation and elimination plays a critical role in a variety of pathologic conditions. ROS levels have been observed in several hematopoietic malignancies including acute and chronic myeloid leukemia. ELF-EMFs exposure significantly decreased Nitric oxide synthase (iNOS) protein expression Lower levels of NO have been demonstrated to exert a protective function in leukemic and melanoma cells and to inhibit effector caspases by S-nitrosylation. Also ELF-EMFs can decrease melatonin production by effects on N-acetyltransferase. Melatonin is an antioxidant, effective in protecting nuclear DNA. Transmitters emitting radio frequency electromagnetic fields (RF-EMFs) are usually not located in populated areas but some epidemiology studies showed association distance transmitters from residential area and leukemia.



Extremely low frequency (ELF); Radio frequency electromagnetic fields (RF-EMFs); Leukemia; ROS (Reactive oxygen species).

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"Journal of Paramdedical Sciences", is a publication of "School of Paramedical Sciences, Shahid Beheshti University of Medical Sciences" and "Iranian Society of Medical Proteomics".

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EISSN: 2008-4978

PISSN: 2008-496X