Synthesis and investigation of antioxidant activities of 2-benzylidene-3-coumaranones

Hadi Adibi, Alireza Foroumadi, Reza Khodarahmi, Karim Najafi, Mostafa Rezaei-Tavirani

Abstract


153

      A number of 6-hydroxy-2-benzylidene-3-coumaranones were synthesized from condensation of 6-hydroxy-3-coumaranone with appropriate aldehydes and were evaluated for their antioxidant activities. The antioxidant activity was assessed using two methods, including, 1,1-biphenyl-2-picrylhydrazyl (DPPH) radical scavenging, and reducing power assays. Some of the benzylidene coumaranones showed antioxidant activity more than Trolox as reference antioxidant.


Keywords


Antioxidant activity; Coumaranones; Silica sulfuric acid; Ferric reducing antioxidant power assay; DPPH.

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DOI: https://doi.org/10.22037/jps.v4i2.4416

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"Journal of Paramdedical Sciences", is a publication of "School of Paramedical Sciences, Shahid Beheshti University of Medical Sciences" and "Iranian Society of Medical Proteomics".

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EISSN: 2008-4978

PISSN: 2008-496X