https://journals.sbmu.ac.ir/jlms/issue/feedJournal of Lasers in Medical Sciences2024-02-06T05:25:57+00:00Farzaneh Moghimkhan jlasers@sbmu.ac.irOpen Journal Systems<p>The <strong><span style="color: #c21807;">Journal of Lasers in Medical Sciences ( JLMS) </span></strong>is a scientific <strong><span style="color: #c21807;">Continuously</span></strong><strong>*</strong> publication of the <strong><a href="http://sbmu.ac.ir/index.jsp?siteid=151">Laser Application in Medical Sciences Research Center</a>, </strong><a href="http://www.sbmu.ac.ir/" target="_blank" rel="noopener"><strong>Shahid Beheshti University of Medical Sciences</strong>.</a> This journal accepts original papers, review articles, case reports, brief reports, case series, photo essays, letters to the editor, and commentaries in the field of<strong> Laser</strong> or <strong>Light</strong> in any field of medicine such as the following medical specialties: Dermatology, General and Vascular Surgery, Oncology, Cardiology, Dentistry, Urology, Rehabilitation, Ophthalmology, Otorhinolaryngology, Gynecology & Obstetrics, Internal Medicine, Orthopedics, Neurosurgery, Radiology, Pain Medicine (Algology). Journal of Lasers in Medical Sciences has received a scientific and research score from the National Medical Publication Committee.</p> <p><strong>*JLMS</strong> was a quarterly publication from 2010 to 2020. We changed the type of publication to <strong><span style="color: #c21807;">Continuously</span></strong> from 2021 and publish a volume continuously (one volume) each year. Also, the print publication type publishes at the end of each year.</p> <p> </p>https://journals.sbmu.ac.ir/jlms/article/view/43420Therapeutic Effects of Exosome Therapy and Photobiomodulation Therapy on the Spermatogenesis Arrest in Male Mice After Scrotum Hyperthermia2023-11-08T09:37:56+00:00Fakhrosadat Tabatabaeehoomanabs@gmail.comShahram Darabihoomanabs@gmail.comReza Soltanihoomanabs@gmail.comFakhroddin Aghajanpourhoomanabs@gmail.comAzar Afsharhoomanabs@gmail.comHojjat-allah Abbaszadehhoomanabs@gmail.comHassan Rajabi-Mahamhoomanabs@gmail.com<p><strong>Introduction:</strong> In men, several factors cause infertility, among which we can mention damage to sperm due to high temperature. So far, various treatments have been proposed for it, but they have not been highly effective. The current study aimed to evaluate the effect of exosome therapy (EXO) and photobiomodulation therapy (PBMT) on spermatogenesis arrest in male mice after scrotum hyperthermia.<br /><strong>Methods:</strong> In this experimental study, the animals were divided into four groups: control, scrotal hyperthermia, scrotal hyperthermia+EXO (100 μL/d) (mice were treated for 30 days), scrotal hyperthermia+PBMT (laser of 0.03 J/cm2 for 30 seconds/for 30 days). Hyperthermia was induced<br />by exposure to the temperature of 43 °C for 20 minutes every day 5 times. After 6 weeks, the animals were sacrificed.<br /><strong>Results:</strong> The treated groups showed a significant increase in sperm parameters compared to the hyperthermic groups. Moreover, these favorable effects were observed in relation to the volume of testicular tissue, the number of germ cells, Leydig cells, and Sertoli cells, and the level of testosterone. Research on antioxidants showed a significant reduction in oxidized glutathione (GSSG) and reactive oxygen species (ROS) in the treatment groups in comparison to the hyperthermia group (P<0.001). Also, there has been a significant increase in the amount of hydrogen peroxide enzyme observed in the hyperthermia group as opposed to the treatment group (P<0.001).<br /><strong>Conclusion:</strong> These findings show that EXO and PBMT can improve spermatogenesis caused by hyperthermia, reduce ROS and GSSG, and increase glutathione (GSH) and sperm quality.</p>2024-03-03T00:00:00+00:00Copyright (c) 2024 Journal of Lasers in Medical Scienceshttps://journals.sbmu.ac.ir/jlms/article/view/43790Comparative Efficacy of Postoperative Compression Methods After EVLT for Great Saphenous Vein Insufficiency2024-02-06T05:25:57+00:00Niki Tadayonnntadayon@gmail.comMostafa Mousavizadehnntadayon@gmail.comFateme Yousefi moghaddamnntadayon@gmail.comFaezeh Jadidiannntadayon@gmail.comMohammadmoein Mirhosseininntadayon@gmail.comNaser Hadavandnntadayon@gmail.com<p><strong>Introduction:</strong> The preference for endovascular techniques in treating varicose veins, particularly in the great saphenous vein (GSV), has increased due to their minimally invasive nature and reduced complications. Post-operative care, especially involving compression therapy, remains crucial to improve outcomes, prevent varicose vein recurrence, and enhance overall recovery. This study aimed to evaluate the efficacy of eccentric compression therapy compared to alternative post-operative care methods following endovenous laser treatment (EVLT) for GSV insufficiency.<br /><strong>Methods:</strong> This prospective randomized clinical trial encompassed 88 EVLT procedures for GSV insufficiency. The participants were divided into two groups, each receiving different postoperative compression methods, and were evaluated over a specified period. The primary outcome was the pain scale after EVLT; meanwhile, the secondary outcome measured in the present study was the rate of GSV occlusion after EVLT.<br /><strong>Results:</strong> Both groups underwent all EVLT procedures successfully without any complications. At the one-month duplex ultrasound (DUS) follow-up, the sapheno-femoral junction occlusion rates were 97% (43 out of 44) for group A (eccentric compression plus gradual compression stocking) and 95% (42 out of 44) for group B (only gradual compression stocking). Ecchymosis was observed in only 12 patients across both groups, accounting for an overall occurrence of 13.6%. Group A patients reported significantly lower analgesic usage (10%) compared to group B (18%), although this difference did not reach statistical significance. Analysis of postoperative pain data utilizing the visual analog scale (VAS) showed a median value of 5.5 in group B patients, which decreased to 3.1 with the application of eccentric compression. Moreover, there was less ecchymosis in group A observed by one week.<br /><strong>Conclusion:</strong> This study contributes to the ongoing discourse on the efficacy of postoperative compression in varicose vein treatment. It underscores the necessity for more comprehensive, well-designed studies to yield clearer conclusions and provide better guidance for postprocedure care.</p>2024-02-28T00:00:00+00:00Copyright (c) 2024 Journal of Lasers in Medical Scienceshttps://journals.sbmu.ac.ir/jlms/article/view/43050Laser Applications in Regenerative Endodontics: A Review2023-10-30T07:43:38+00:00Farzaneh Ahrarifarzaneh.ahrari.1400@gmail.comSalehe Akhondians.akhondian@gmail.comReza Shakibarshakiba981@gmail.comAfsaneh Tolooeiafsaneh781114@gmail.comArmaghan Salehiarmaghan.slh@gmail.comMaryam ValizadehValizadehmr981@mums.ac.irKosar Hosseini kosarhosseini79ums@gmail.com<p><strong>Introduction:</strong> Developing regenerative endodontic treatment (RET) is an exciting approach to managing immature permanent teeth with pulp necrosis. RET is usually performed in two clinical steps: disinfection (first step) and tissue engineering (second step). Recently, laser therapy has entered the field of RET. This study aimed to provide an overview of the literature that employed laser therapy for root regeneration.<br /><strong>Methods:</strong> A comprehensive search was performed on four databases, including PubMed, Web of Science, Scopus, and Google Scholar. The searched keywords were laser, regenerative endodontics, immature permanent teeth, and dental pulp necrosis, and related English-published articles were included up to October 2023.<br /><strong>Results:</strong> Thirteen studies utilized a laser for RET. In the first step of RET, both high-power and low level lasers (through photodynamic therapy [PDT]) may be applied for canal disinfection. In contrast, regenerative procedures in the second step of RET are just accelerated by low-power lasers (biostimulation). The literature does not support the benefit of laser-assisted irrigation in improving the clinical success of RET. There is some evidence that laser-assisted disinfection with a diode laser may provide comparable results to triple antibiotic paste in reducing bacterial counts in root canals while providing slightly better clinical and radiographic outcomes. PDT may be an effective and suitable adjunct to conventional disinfection methods in immature, necrotic teeth.<br /><strong>Conclusion:</strong> Low-power lasers may be beneficial tools for improving the results of regenerative endodontics through chemical disinfection in the first step (PDT) or by biostimulation in the second step of RET.</p>2024-02-04T00:00:00+00:00Copyright (c) 2024 Journal of Lasers in Medical Sciences