• Logo
  • SBMUJournals

Clinical Evaluation of the Efficacy of Neodymium-Doped Yttrium Aluminium Garnet (Nd: YAG) Laser Therapy and Sensikin® in Treatment of Dentine Hypersensitivity

Ahmad Moghareh Abed, Narges Naghsh, Reza Birang, Fatemeh Shafiei, Jaber Yaghini, Massoud Seifi




INTRODUCTION: Dentine hypersensitivity (DH) is characterized by a short sharp pain arising from the exposed dentine, in response to a thermal, evaporative, tactile, osmotic or chemical stimulus. The aim of this study was to evaluate the efficacy of Nd:YAG laser therapy and desensitizing gel (Sensikin®, Laboratorios Kin S.A., Barcelona, Spain) in treatment of dentine hypersensitivity.

METHODS: A total of 20 patients with at least 6 hypersensitive teeth were selected and divided randomly into three groups: Nd:YAG laser (10 HZ, 1W, 60 S, two times) treated group, Sensikin® treated group and a control group. Subjects were asked to apply the gel at home for the next week and 3 times a day as they were instructed. Assessment of the pain was performed by visual analyzing scale (VAS) after stimulation of the teeth by compressed air at 6 intervals: before treatment, immediately after treatment, one week, one, three and six months later. The data obtained were analyzed using the SPSS software, one way ANOVA and repeated measurement ANOVA tests.

RESULTS: VAS scores did not show any significant differences between the three groups prior to treatment (P value>0.05), but in all groups after treatment VAS scores differed significantly in comparison to VAS scores before treatment (Pvalue<0.05). This statistically significant difference in the control group demonstrated a placebo effect. However, the efficacy between the three groups was not significantly different. An overall comparison indicated no significant differences at various time intervals.

CONCLUSION: Nd:YAG laser and desensitizing gel effectively reduce DH. However, we found no significant statistical differences between these two groups compared with the control group. 


dentine hypersensitivity; Nd:YAG laser; laser therapy.


Ladalardo TC, Pinheiro A, Campos RA, Brugnera Júnior A, Zanin F, Albernaz PL, Weckx LL. Laser therapy in the treatment of dentine hypersensitivity. Braz Dent J. 2004;15(2):144-50.

Flynn N, Galloway R, Orchardson R.The incidence of hypersensitive teeth in the West of Scotland.J Dent. 1985: 13: 230–6.

Graf HE, Galasse R. Morbidity, prevalence and intra-oral distribution of hypersensitive teeth.J Dent Res.1977; 56: 479.

Iwrin CR, McCusker P. Prevalence of dentine hypersensitivity in general population.J Ir Dent Assoc.1997; 43: 7–9.

Rees JS. The prevalence of dentine hypersensitivity in general dental practice in the UK. J Clin Periodontol.2000; 27: 860–5.

Fischer C, Fischer RG, Wennberg A. Prevalence and distribution of cervical dentine hypersensitivity in a population in Rio de Janeiro, Brazil. J Dent.1992: 20:272–6.

Irvine JH. Root surface sensitivity: a review of aetiology and management. J N Z Soc Periodontol. 1988 Nov;(66):15-8.

Addy M, West N. Etiology, mechanisms and management of dentine hypersensitivity. Curr Opin Periodontol.1994: 71–7.

Chabanski MB, Gillam DG.Aetiology, prevalence and clinical features of cervical dentine sensitivity: a review. J Oral Rehab.1997: 24(1): 15–9.

Walters PA. Dentinal hypersensitivity: a review. J Contemp Dent Pract.2005; 6(2): 107-17.

Chabanski MB, Gillam DG, Bulman JS, Newman HN. Clinical evaluation of cervical dentine sensitivity in a population of patients referred to a specialist periodontology department: a pilot study. J Oral Rehabil. 1997 Sep;24(9):666-72.

Irvine JH, Horsfield JA, McKinney CZ, Tate WP. A novel strategy to interfere with human immunodeficiency virus type 1 propagation. N Z Med J. 1998 Jun 26;111(1068):222-4.

Rapp R, Avery JK, Strachen DS.Possible role of the aceylcholinesterase in neural conduction within the dental pulp. In:FinnSB, editor. Biology of dental pulp organ. Birmingham: University of Alabama Press,1968: 309.

Brännström M. A hydrodynamic mechanism in the transmission of pain-produced stimuli through the dentine. In:AndersonDJ, editor. Sensory mechanisms in dentine. London: Pergamon Press,1963: 73–9.

Grossman LI . A systematic method for the treatment of hypersensitive dentine. J. Am. Dent. Assoc. 1935: 22, 592.

Orchardson R, Gillam DG. Managing dentin hypersensitivity. J Am Dent Assoc. 2006; 137(7): 990- 8; 1028-9.

West NX. Dentine hypersensitivity: preventive and therapeutic approaches to treatment. Periodontol 2000. 2008; 48: 31-41.

Kimura Y, Wilder-Smith P, Yonaga K, Matsumoto K. Treatment of dentine hypersensitivity by lasers: a review. J Clin Periodontol. 2000; 27(10):715-21.

Birang R, Poursamimi J, Gutknecht N, Lampert F, Mir M. Comparative evaluation of the effects of Nd:YAG and Er:YAG laser in dentin hypersensitivity treatment. Lasers Med Sci. 2007; 22(1): 21-4.

Lier BB, Rösing CK, Aass AM, Gjermo P.Treatment of dentin hypersensitivity by Nd:YAG laser. J Clin Periodontol. 2002; 29(6): 501-6.

Matsumoto K, Funai H, Shirasuka T, Wakabayashi H. Effects of Nd:YAG laser in treatment of cervical hypersensitive dentine. J Conserv Dent. 1985; 28: 760–65. Japanese

Ritter AV, de L Dias W, Miguez P, Caplan DJ, Swift EJ Jr.Treating cervical dentin hypersensitivity with fluoride varnish: a randomized clinical study. J Am Dent Assoc. 2006; 137(7): 1013-20.

Gaffar A. Treating hypersensitivity with fluoride varnishes. Compend Contin Educ Dent. 1998; 19(11): 1088-90,1092, 1094 passim.

Hu D, Zhang YP, Chaknis P, Petrone ME, Volpe AR, DeVizioW. Comparative investigation of the desensitizing efficacy of a new dentifrice containing 5.5% potassium citrate: an eight-week clinical study. J Clin Dent.2004; 15(1): 6-10.

Pereira R, Chava VK.Efficacy of a 3% potassium nitrate desensitizing mouth wash in the treatment of dentinal hypersensitivity.J Periodontol. 2001; 72(12): 1720-5.

Tarbet WJ, Silverman G, Stolman JM, Fratarcangelo PA. Clinical evaluation of a new treatment for dentinal hypersensitivity. J Periodontol.1980; 51(9): 535-40.

Aranha AC, Pimenta LA, Marchi GM.Clinical evaluation of desensitizing treatments for cervical dentin hypersensitivity. Braz Oral Res. 2009; 23(3): 333-9.

Kienle GS, Kienle H. The powerful placebo effect: fact or fiction? J Clin Epidemiol. 1997; 50(12): 1311-18.

Berman LH. Dentinal sensation and hypersensitivity. A review of mechanisms and treatment alternatives. J Periodontol.1985; 56: 216–22.

Tilliss TS, Keating JG. Understanding and managing dentin hypersensitivity. J Dent Hyg. 2002;76(4):296-310.

Lopes BM, Theodoro LH, Melo RF, Thompson GM, Marcantonio RA. Clinical and microbiologic followup evaluations after non-surgical periodontal treatment with erbium:YAG laser and scaling and root planing. J Periodontol. 2010;81(5):682-91.

Rotundo R, Nieri M, Cairo F, Franceschi D, Mervelt J, Bonaccini D, et al. Lack of adjunctive benefit of Er:YAG laser in non-surgical periodontal treatment: a randomized split-mouth clinical trial. J Clin Periodontol. 2010;37(6):526-33.

Yilmaz HG, Kurtulmus-Yilmaz S, Cengiz E, Bayindir H, Aykac Y. Clinical evaluation of Er,Cr:YSGG and GaAlAs laser therapy for treating dentine hypersensitivity: A randomized controlled clinical trial. J Dent. 2011;39(3):249-54.

Yilmaz HG, Cengiz E, Kurtulmus-Yilmaz S, Leblebicioglu B. Effectiveness of Er,Cr:YSGG laser on dentine hypersensitivity: a controlled clinical trial. J Clin Periodontol. 2011;38(4):341-6.

He S, Wang Y, Li X, Hu D. Effectiveness of laser therapy and topical desensitising agents in treating dentine hypersensitivity: a systematic review. J Oral Rehabil. 2011;38(5):348-58..

Cunha-Cruz J. Laser therapy for dentine hypersensitivity. Evid Based Dent. 2011;12(3):74-5.

DOI: https://doi.org/10.22037/jlms.v3i2.2843

Comments on this article

View all comments