• Logo
  • SBMUJournals

Laser Therapy Versus Electromagnetic Field on Mucosal Membrane Thickening in Children with Chronic Rhinosinusitis

Nessrein Afify Abdelrashid, Hamada El-Sayed Ayoub, Ahmed Mamdouh Abdelkader




Introduction: Rhinosinusitis is a frequent disease in children but may be underdiagnosed, that is to say, several causes of the disease are missed in children. Therefore, it seems essential to provide other modalities to treat chronic health conditions like such cases. This controlled clinical study was conducted to compare the effect of two non-pharmacological, painless, safe modalities; low-level laser therapy (LLLT), with pulsed electromagnetic field (PEMF) on mucosal membrane thickening in children with chronic rhinosinusitis.

Methods: Thirty children with chronic sinusitis participated in this study, their ages ranged from 6 to 13 years old, recruited from the outpatients ENT clinic, Kasr Al Aini teaching hospital. They were classified into 2 groups of equal number; study group A (PEMF group) and study group B (LLLT group). These children were evaluated before the starting and after the end of the study through CT scan full examination (coronal and axial) for all children.

Results: This study showed that there were statistically significant improvements in mucosal membrane thickness in both groups (P < 0.05), while there was no statistically significant difference between groups (P > 0.05).

Conclusion: From the obtained outcomes it can be concluded that both the laser and electromagnetic field can be used effectively in the management of symptoms in children with chronic rhinosinusitis, while no significant difference between these modalities obtained.


CT scan; LLLT; PEMF; Mucosal membrane thickness; Rhinosinusitis


Slavin RG, Spector SL, Bernstein IL, et al. The diagnosisand management of sinusitis: a practice parameter update. J Allergy ClinImmunol. 2005;116 (6 Suppl):S13-47.

Meltzer EO, Hamilos DL, Hadley JA, et al. Rhinosinusitis: establishing definitions for clinical research and patient care. J Allergy Clin Immunol. 2004;114(6 Suppl):155-212. doi:10.1016/j.otohns.2004.09.067.

Stevens HE. Allergic and inflammatory aspects of chronic Rhinosinusitis. J Otolaryngol. 1991;20(6):395-399. Ah-See K. Sinusitis (acute). BMJ Clin Evid (Online). 2011;2011:0511.

Orlandi RR, Kennedy DW. Surgical management of Rhinosinusitis. Am J Med Sci. 1998;316(1):29-38. Doi:10.1016/S0002-9629(15)40368-4.

McQuillan L, Crane LA, Kempe A. Diagnosis and management of acute sinusitis by pediatricians. Pediatrics. 2009;123(2):e193-e198. doi: 10.1542/peds.2008-2479.

Ferguson BJ. Categorization of eosinophilic chronic rhinosinusitis. Curr Opin Otolaryngol Head Neck Surg. 2004;12(3):237-242.

Marple BF, Ryan MW. Allergic fungal rhinosinusitis: diagnosis and management. Curr Opin Otolaryngol Head Neck Surg. 2007;15(1):18-22. doi: 10.1097/MOO.0b013e328013dbd9

Karu T. Biomedical Photonic Handbook. New York: CRC Press; 2003:1-6.

Passarella S, Ostuni A, Atlante A, Quagliariello E. Increase in the ADP/ATP exchange in rat liver mitochondria irradiated in vitro by helium-neon laser Biochem BiophysRes Commun. 1988;156:978-86.

Vadalà M, Vallelunga A, Palmieri L, Palmieri B, Morales-Medina JC, Iannitti T. Mechanisms and therapeutic applications of electromagnetic therapy in Parkinson’s disease. Behav Brain Funct. 2015;11:26. doi: 10.1186/ s12993-015-0070-z.

Imants D, Laimdota D, Ilgonis K, Arta T, Bella A, Leonid S. Experimental study of the effect of electromagnetic fields in early stage of wound healing. Bioelectrochem Bioenerg.1994;35:13-17.

Strauch B, Herman C, Dabb R, Ignarro LJ, Pilla AA. Evidence-Based use of pulsed electromagnetic field therapy in clinical plastic surgery, Aesthet Surg J. 2009;29 (2):135-doi: 10.1016/j.asj.2009.02.001.

Santini MT, Ferrante A, Romano R, et al. A 700 MHz1H-NMR study reveals apoptosis-like behavior in human K562 erythroleukemic cells exposed to a 50 Hz sinusoidal magnetic field. Int J Radiat Biol. 2005;81(2):97-113. doi:


Toshikawa T, Taniqawa M, Taniqawa T, Imai A, Honqo H, Kondo M. Enhancement of nitric oxide generation by low frequency electromagnetic field, Pathophysiology. 2000;7(2):131-135.

Tuner J, Hode L. The Laser Therapy Handbook. Sweden: Prima Books; 2004: 43.

Kneebone WJ. Practical applications of low level lasertherapy. Pract Pain Manag. 2006;6(8):34-40.

Lopez RM, Vilchez MA, Gargallo AJ, Arnabat DJ, Gay EC. Efficacy of low level laser therapy in the management of pain facial swelling, and postoperative traismus after a lower third molar extraction, a preliminary study. Lasers Med Sci. 2012;27(3):559-566. doi: 10.1007/s10103-011-0936-8.

Bjordal JM, Johnson MI, Iversen V, Aimbire F, Lopez-Martins RA. Low level laser therapy in acute pain: a systematic review of possible mechanism of action and clinical effects in randomized placebo-controlled trials. Photomed Laser Surg. 2006;24(2):158-68. doi: 10.1089/pho.2006.24.158.

Kruchinina I, Feniksova LV, Rybalkin SV, Pekli FF.Therapeutic effect of helium-neon laser on microcirculation

of nasal mucosa in children with acute and chronic maxillary sinusitis as measured by conjunctival biomicroscopy. Vestn

Otorinolaringol. 1991;(3):26-30.

DOI: https://doi.org/10.22037/jlms.v10i3.22105