Anesthesia in a pediatric patient with Xeroderma pigmentousoma: A case report
Iranian Journal of Pediatric Surgery,
Vol. 5 No. 1 (2019),
15 June 2019
Xeroderma pigmentosum (XP) is an autosomal recessive genetic disorder with the following conditions: neurologic disorders that gradually progress and skin hypersensitivity to ultraviolet (UV). Inhalational anesthetic drugs should be avoided in these patients since they may induce DNA damage, also use of muscle relaxants should be kept to a minimum. Thus for XP patients, total intravenous anesthesia (TIVA) is more appropriate for inducing general anesthesia and airway manipulation must be kept to a minimum. We report a 6 year old boy with XP and its airway management and anesthesia during surgery
- Xeroderma pigmentosum
- general anesthesia
- total intravenous anesthesia
Mahin S, Marjan D, Mehdi G, et al: Airway Management in a Pediatric Patient with Xeroderma Pigmentosum: A Case Report. Advances in Bioscience and Clinical Medicine 2015;3(1):53-5.
Mulimani SM, Talikoti DG: A child with xeroderma pigmentosum for excision of basal cell carcinoma. Saudi journal of anaesthesia 2013;7(4):467.
Fjouji S, Bensghir M, Yafat B, et al: Postoperative neurological aggravation after anesthesia with sevoflurane in a patient with xeroderma pigmentosum: a case report. Journal of medical case reports 2013;7(1):73.
Reitz M, Lanz E: DNA strand breaks in cells with DNA repair deficiency after halothane exposure in vitro. Arzneimittel-Forschung 1993;43(4):418-20.
Zuo Z: Are volatile anesthetics neuroprotective or neurotoxic? Medical gas research 2012;2(1):10.
Ubale P, Baldwa N, Katariya K,et al: Anesthetic management in a case of xeroderma pigmentosum. Anaesthesia, Pain & Intensive Care 2015;19(4).
Lighthall G, Harrison TK, Chu LF: Laryngeal mask airway in medical emergencies. The New England journal of medicine 2014;370(9):883.
Soen M, Kagawa T, Uokawa R, et al: Anesthetic management of a patient with xeroderma pigmentosum. Masui The Japanese journal of anesthesiology 2006;55(2):215-7.
Oliveira CRD, Elias L, Barros ACdM, et al: Anesthesia in patient with Xeroderma pigmentosum: case report. Revista brasileira de anestesiologia 2003;53(1):46-51.
Shrestha G, Sah R, Amatya A, et al: Anaesthetic management of patients with Xeroderma pigmentosum. A series of three cases. Nepal Medical College journal: NMCJ 2011;13(3):231-2.
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