• Logo
  • SBMUJournals

Epidemiological, Clinical and Paraclinical Study of Hydatid Cysts in Three Educational Medical Centers in 10 Years

Simindokht Shoaee, Mohammad Rezvanizadeh, Mehrdad Haghighi, Hooman Yousefi
539

Views

PDF

Abstract

Background: Echinococcosis or hydatidosis, caused by the larval stage of Echinococcus granulosus (E. granulosus), is an important public health problem in many areas of the world  and  Iran is a country of endemic situation for hydatidosis In the present study, we evaluated epidemiological, complications and clinical characteristics of hydatidosis at three University Medical Centers in Tehran over a 10-year period.

Materials and Methods: This is a descriptive cross-sectional study performed in patients with hydatid cysts. Information about age, gender, number of cysts, organ involvement, morbidity and mortality and relapse were collected from medical records of hydatid patients. Paraclinic information such as CT Scan, MRI, ultrasound, complete blood count, pathological diagnosis and complication of disease were collected.

Results: Overall, 81 patients, 35 (43.2%) male and 46 (56.8%) female, who were diagnosed as having hydatid cyst by clinical and radiological findings, with pathologic documentation were studied in three university medical center registries over a 10-year period (2003- 2012) in Tehran. Fourteen patients (17% of cases) had complications resulting from this disease. Patients' age ranged from 5 to 86 years, and the peak prevalence of the disease was between 20 and 40 (34% of cases).

Conclusion: Iran  is a country of endemic situation for hydatidosis. Prevalence rate of hydatidosis in Iran was reported to be 0.61-2 in 100000 populations. The highest  rate of infection and complications were in patients of 20-40 years age. Clinical examination revealed that abdominal pain was the most common complaint and was present in 51.7% of the cases. Other most common complain were cough, abdominal mass, dyspnea, icterus, chest pain, dyspepsia, back pain and seizure; and it was result of occupying effect of cysts in organs. This is similar with previous studies in Iran


Keywords

hydatidosis, Echinococcosis, Epidemiology

References

Fauci AS. Harrison's principles of Internal Medicine: McGraw-Hill. New York. 2008;2.

Heidari Z, Mohebali M, Zarei Z, Aryayipour M, Eshraghian M, Kia E, et al. Seroepidemiological study of human hydatidosis in Meshkinshahr district, Ardabil province, Iran. Iranian journal of parasitology. 2011;6(3):19.

Eckert J, Deplazes P. Biological, epidemiological, and clinical aspects of Echinococcosis, a zoonosis of increasing concern. Clinical Microbiology Reviews. 2004;17(1):107-35.

Ahmadi, N. and A. Dalimi, Characterization of Echinococcus granulosus isolates from human, sheep and camel in Iran. Infection, Genetics and Evolution, 2006;6(2):85-90.

Moro PL, et al. Practices, knowledge and attitudes about human hydatidosis in Peru. Rev Gastroenterol Peru. 2008;28(1):43-9.

Oku Y, et al. Control program against hydatidosis and the decreased prevalence in Uruguay. Elsevier, International Congress Series. 2004.

Torgerson PR, Deplazes P. Echinococcosis: Diagnosis and diagnostic interpretation in Population studies. Trends in parasitology. 2009;25(4):164-70.

Tepetes K, Christodoulidis G, Spryridakis M, Hatzitheofilou K. Large solitary retroperitoneal echinococcal cyst: a rare case report. World journal of gastroenterology: WJG. 2007;13(45):6101-3.

Montazeri, V, Sokouti M, Rashidi H. Comparison of pulmonary hydatid disease between children and adult. Tanaffos. 2007;6(1):13-18.

Rokni M. The present status of human helminthic diseases in Iran. Annals of tropical medicine and parasitology. 2008;102(4):283-95.

Eslami A, Hosseini SH. Echinococcus granulosus infection of farm dogs of Iran. Parasitology research, 1998;84(3):205-7.

Maleky, F. and M. Moradkhan, Echinococcosis in the stray dogs of Tehran, Iran. Annals of tropical medicine and parasitology. 2000;94(4):329-31.

Ansari-Lari M. A retrospective survey of hydatidosis in livestock in Shiraz, Iran, based on abattoir data during 1999–2004. Veterinary parasitology. 2005;133(1):119-23.

Harandi MF, Budke CM, Rostami S.The monetary burden of cystic echinococcosis in Iran. PLOS neglected tropical diseases. 2012;6(11):1915.

Priego P, et al. Hepatic hydatidosis. Radical vs. conservative surgery: 22 years of experience. Revista Espanola de Enfermedades Digestivas. 2008;100(2):82-5.

Rokni M. Echinococcosis/hydatidosis in Iran. Iranian J Parasitol, 2009;4(2):1-16.

Shambesh MA, et al. An extensive ultrasound and serologic study to investigate the prevalence of human cystic echinococcosis in northern Libya. The American journal of tropical medicine and hygiene. 1999;60(3):462-8.

Al-Shibani L. Cases of hydatidosis in patients referred to Governmental hospitals for cyst removal in Sana’a City, Republic of Yemen. Trop Biomed, 2012;29(1):18r23.

Arbabi M, Masoud J, Dalimi Asl A, Sajadi M. Seroepidemiologic prevalence of Hydatid cyst in Hamadan 1991. KAUMS Journal (FEYZ). 1998;2(2):43-50.

Fallah E, Nazer M, Mehdipourzare N. Study of hydatidosis during 1995 and 2002 in East-Azarbaijan province. 5th National Iranian Congress of Parasitology Tehran, Iran. 2004. 480:15-17.

Alghoury A, El-Hamshary E, Azazy A, Hussein E, Rayan HZ. Hydatid disease in Yemeni patients attending public and private hospitals in Sana’a city, Yemen. Oman medical journal. 2010;25(2):88.

Mousavi S, Samsami M, Fallah M, Zirakzadeh H. A retrospective survey of human hydatidosis based on hospital records during the period of 10 years. Journal of Parasitic Diseases. 2012;36(1):7-9.

Çelik M, et al. Surgical treatment of pulmonary hydatid disease in children: report of 122 cases. Journal of pediatric surgery, 2000;35(12):1710-3.

Ahmadi N, Badi F. Human hydatidosis in Tehran, Iran: A retrospective epidemiological study of surgical cases between 1999 and 2009 at two university medical centers. Trop Biomed. 2011;28(2):450-6.

Sarkari B, Sadjjadi S, Beheshtian M, Aghaee M, Sedaghat F. Human cystic Echinococcosis in Yasuj district in Southwest of Iran: an epidemiological study of seroprevalence and surgical cases over a ten‐year period. Zoonoses and public health. 2010;57(2):146-50.

Shir-Yazdi M. Characteristics of the patients affected by hydatid cyst in the province of Yazd between the years 1991-1998. The Journal of Shaheed Sadoughi University of Medical Sciences. 1990;8(1):25-9.




DOI: https://doi.org/10.22037/nbm.v4i1.7643