A Study of Contractility of Proximal Surgical Margin in Esophageal Cancer

Jalaluddin khoshnevis--- 1. Cancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran 2. Dept. of General and Vascular Surgery, Shahid Beheshti University of Medical Sciences, Tehran, Iran,
Afshin Moradi--- Cancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran,
Eznollah azarghashb--- 1. Cancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran 2. Dept. of Health and Social Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran,
Barmak Gholizade--- 1. Cancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran 2. Dept. of General and Vascular Surgery, Shahid Beheshti University of Medical Sciences, Tehran, Iran,
Mohammad Reza Sobhiyeh--- 1. Cancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran 2. Dept. of General and Vascular Surgery, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Abstract


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Background: The marginal length from main tumor in esophageal cancer is a considerable issue regarding surgical management and adjuvant treatment; so we decided to study the contractility effect on the proximal surgical margin after immersing it in10% buffered formalin as a fixative.

Methods: The proximal marginal length of  ten sequential patients with esophageal cancer who underwent transhiatal esophagectomy were studied, on the operating table as fresh specimens, immediately after resection, and next 24, 48 and 72 hours after immersing in 10% buffered formalin.

Results: The contraction continued through the day 3, the mean contractility after one day was about 27%, after two days was 33% and after three days was 38%.

Conclusion: This study shows how the proximal esophageal margin can vary by the time, after immersing in 10% buffered formalin and should be considered in every settings and reporting documents by pathologists.

Keywords: Esophageal cancer; Marginal safety; Contractility

Please cite this article as: Khoshnevis J, MoradiA, Azargashb E, Gholizade B, Sobhiyeh MR. A Study of Contractility of Proximal Surgical Margin in Esophageal Cancer. Iran J Cancer Prev.2013; 6(1): 25-7.

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