Thrombotic Thrombocytopenic Purpura Following Honeybee Envenomation: A Case Report
International Journal of Medical Toxicology and Forensic Medicine,
Vol. 10 No. 2 (2020),
21 June 2020
Background: Thrombotic Thrombocytopenic Purpura (TTP) is a rare and life-threatening disorder characterized by severe thrombocytopenia, microangiopathic hemolytic anemia, fever, renal dysfunction, and neurological deficient. TTP leads to the formation of blood clots in small blood vessels throughout the body. TTP is associated with many risk factors such as pregnancy, HIV, cancer, lupus, and infections. Recently there have been few published case reports of bee sting associated TTP.
Methods: A 67-year-old man from a rural area of the Southwest Province of Iran, Ilam, was referred to the academic general hospital because of fever, chills, sweating, vomiting and dizziness following the honeybee sting on his body.
Results: this study showed that,multiple co-morbidities including CVD and diabetes, along with coagulation abnormalities after honeybee stings, seriously exacerbated patient hemodynamic status.
Conclusion: TTP, as a major complication due to the toxic reaction of a large number of bee stings with underlying diseases in patients, should be given more attention.
- Thrombotic Thrombocytopenic Purpura (TTP)
- Honey bee sting
- Anaphylactic shock
How to Cite
Ashley JR, Otero H, Aboulafia DM. Bee envenomation: A rare cause of thrombotic thrombocytopenic purpura. South Med J. 2003; 96(6):588-91. [DOI:10.1097/01.SMJ.0000051056.23320.09] [PMID]
Withana M, Rodrigo C, Gnanathasan A, Gooneratne L. Presumptive thrombotic thrombocytopenic purpura following a hump-nosed viper (Hypnale hypnale) bite: A case report. J Venom Anim Toxins Incl Trop Dis. 2014. 20(1):26. [DOI:10.1186/1678-9199-20-26] [PMID] [PMCID]
Bailey M, Maestas T, Betancourt R, Mikhael D, Babiker HM. A rare cause of Thrombotic Thrombocytopenia Purpura-(TTP-) like syndrome, vitamin B12 deficiency: Interpretation of significant pathological findings. Case Rep Hematol. 2019; 2019:1529306.. [DOI:10.1155/2019/1529306] [PMID] [PMCID]
Jen KY, Laszik ZG, EndotheLiopathies: Hemolytic uremic syndrome, thrombotic thrombocytopenic purpura, and preeclampsia, Pathobiol Hum Dis. 2014; 2767-87. [DOI:10.1016/B978-0-12-386456-7.05406-X]
Scully M, Cataland S, Peyvandi F. Undrestanding TTP [Internet]. 2020 [cited 2020 Jan 16]. Available from: https://www.understandingttp.com/hcp/about-ttp/.
Moschcowitz, E. Hyaline thrombosis of the terminal arterioles and capillaries: a hitherto undescribed disease. Thromb Haemost. 1978; 40(1):4-8. [PMID]
Murthy PR, Ajith Karanth AK, Karanth S, Kalashetty M., Thrombotic thrombocytopenic purpura in a patient with snake bite. Indi-an J Case Reports. 2019. 5(3):277-9. [DOI:10.32677/IJCR.2019.v05.i03.028]
Light WC, Robert MD, Reisman E, Masatoshi Shimizu MD, Carl E, Arbesman MD, et al. Unusual reactions following insect stings: clinical features and immunologic analysis. J Allergy Clin Immunol. 1977. 59(5):391-7. [DOI:10.1016/0091-6749(77)90024-0]
Stack K. Pryor L. Significant traumatic intracranial hemorrhage in the setting of massive bee venom-induced coagulopathy: A case report. Wilderness Environ Med. 2016. 27(3):405-8. [DOI:10.1016/j.wem.2016.05.005] [PMID]
Namdev R, Dutta SR, Singh H. Acute immune thrombocytopenic purpura triggered by insect bite. J Indian Soc Pedod Prev Dent. 2009; 27(1):58. [DOI:10.4103/0970-4388.50821] [PMID]
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